RBP1 and SAP30

Number of citations of the paper that reports this interaction (PMID 15451426)
21

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vivo)

		RBP1	SAP30
Gene Name		retinol binding protein 1, cellular	Sin3A-associated protein, 30kDa
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytosol	Histone Deacetylase Complex Nucleoplasm
	Molecular Function	Transporter Activity Retinoid Binding Retinal Binding Retinol Binding	DNA Binding Transcription Corepressor Activity Protein Binding Metal Ion Binding
	Biological Process	Retinoid Metabolic Process Vitamin A Metabolic Process Transport Phototransduction, Visible Light	Negative Regulation Of Transcription From RNA Polymerase II Promoter Chromatin Organization Transcription, DNA-templated Regulation Of Transcription, DNA-templated Gene Expression Skeletal Muscle Cell Differentiation Regulation Of Gene Expression, Epigenetic Negative Regulation Of Gene Expression, Epigenetic
Pathways		Visual phototransduction The canonical retinoid cycle in rods (twilight vision) Retinoid cycle disease events Diseases associated with visual transduction Retinoid metabolism and transport	NoRC negatively regulates rRNA expression Chromatin modifying enzymes Chromatin organization HDACs deacetylate histones Epigenetic regulation of gene expression Negative epigenetic regulation of rRNA expression
Drugs		Vitamin A Acitretin
Diseases
GWAS
Protein-Protein Interactions		14 interactors: BRMS1 BRMS1L HDAC1 HDAC2 IKBKG ING1 LINC00152 LRAT LRP2 MED26 RBBP4 RBBP7 SAP30 SIN3A	27 interactors: ARID4A BRMS1 BRMS1L CIR1 HBP1 HDAC1 HDAC2 HIST1H2AL HIST2H2BE HIST3H3 HIST4H4 HTT ID3 ING1 LINC00152 MXD1 NCOR1 NCOR2 PCBD1 RBBP4 RBBP7 RBP1 SAMSN1 SAP30BP SIN3A YY1 ZNF395
Entrez ID		5947	8819
HPRD ID		07036	04540
Ensembl ID		ENSG00000114115	ENSG00000164105
Uniprot IDs		P09455	O75446
PDB IDs			2KDP
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Gene Expression, Epigenetic Chromatin Organization Histone Deacetylation Protein Deacetylation Chromatin Modification Chromosome Organization Regulation Of Gene Expression, Epigenetic Transcription, DNA-templated RNA Biosynthetic Process ATP-dependent Chromatin Remodeling Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Transcription From RNA Polymerase II Promoter Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Negative Regulation Of Gene Expression Regulation Of Transcription, DNA-templated RNA Metabolic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Negative Regulation Of Transcription, DNA-templated Regulation Of RNA Metabolic Process Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Gene Expression Histone Modification Biosynthetic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Negative Regulation Of Biosynthetic Process Chromatin Remodeling Organelle Organization Fungiform Papilla Formation Fungiform Papilla Morphogenesis Nucleobase-containing Compound Metabolic Process Positive Regulation Of Receptor Biosynthetic Process Fungiform Papilla Development Heterocycle Metabolic Process Eyelid Development In Camera-type Eye Cellular Aromatic Compound Metabolic Process Hair Follicle Placode Formation Cellular Nitrogen Compound Metabolic Process Tongue Morphogenesis Regulation Of Receptor Biosynthetic Process Negative Regulation Of Cellular Metabolic Process Histone H4 Deacetylation Nitrogen Compound Metabolic Process Regulation Of Cell Death CENP-A Containing Nucleosome Assembly Histone H3 Deacetylation Regulation Of Metabolic Process	Chromosome Organization Negative Regulation Of Gene Expression Chromatin Organization Transcription, DNA-templated Negative Regulation Of Transcription, DNA-templated RNA Biosynthetic Process Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Chromatin Modification Negative Regulation Of Biosynthetic Process Regulation Of Gene Expression, Epigenetic Negative Regulation Of Gene Expression, Epigenetic Gene Expression Heterocycle Metabolic Process Regulation Of Gene Expression Regulation Of Transcription, DNA-templated Regulation Of Nitrogen Compound Metabolic Process RNA Metabolic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Regulation Of RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Negative Regulation Of Cellular Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Nitrogen Compound Metabolic Process Macromolecule Biosynthetic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Organelle Organization Regulation Of Metabolic Process Histone Deacetylation Histone Modification Protein Deacetylation ATP-dependent Chromatin Remodeling Rhythmic Process Histone H3-K9 Modification Transcription From RNA Polymerase II Promoter Circadian Rhythm Chromatin Remodeling CENP-A Containing Nucleosome Assembly Histone Exchange DNA Replication-independent Nucleosome Assembly Homeostatic Process Nucleosome Assembly Cellular Metabolic Process Chromatin Assembly Establishment Of Sertoli Cell Barrier
Tagcloud ?		ascl2 c4b dab2ip dlk1 eya4 fabp3 fzd9 gas7 hdac9 hoxa11 hoxa5 hoxa9 hoxb13 ihh ipf1 isl1 mest mme pax6 ptgs2 rassf1 scgb3a1 sept5 serpina5 sox1 sox17 tbx1 tff1 thy1	affects chip deacetylation detecting differential dual encoded enzyme hdac herpes hsv htrp inhibit interact kmb luciferase lysine msin3a promote real regulator repressor reveal significance simplex synergistically transfer viral whose
Tagcloud (Difference) ?		ascl2 c4b dab2ip dlk1 eya4 fabp3 fzd9 gas7 hdac9 hoxa11 hoxa5 hoxa9 hoxb13 ihh ipf1 isl1 mest mme pax6 ptgs2 rassf1 scgb3a1 sept5 serpina5 sox1 sox17 tbx1 tff1 thy1	affects chip deacetylation detecting differential dual encoded enzyme hdac herpes hsv htrp inhibit interact kmb luciferase lysine msin3a promote real regulator repressor reveal significance simplex synergistically transfer viral whose
Tagcloud (Intersection) ?