DGUOK

Gene Name		deoxyguanosine kinase
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Gene Ontology Annotations	Cellular Component	Nucleus Mitochondrion Mitochondrial Matrix Cytosol
	Molecular Function	Deoxyguanosine Kinase Activity ATP Binding Nucleoside Kinase Activity
	Biological Process	Purine Nucleobase Metabolic Process Protein Phosphorylation Guanosine Metabolic Process Deoxyribonucleoside Monophosphate Biosynthetic Process Nucleotide Biosynthetic Process Negative Regulation Of Neuron Projection Development Purine-containing Compound Salvage Small Molecule Metabolic Process DGTP Metabolic Process Purine Deoxyribonucleoside Metabolic Process Nucleobase-containing Small Molecule Metabolic Process
Pathways		Purine metabolism Metabolism of nucleotides Purine salvage
Drugs
Diseases
GWAS		Dialysis-related mortality ( 21546767) Systemic lupus erythematosus ( 23273568)
Protein-protein Interactions		3 interactors: APP LIG4 PXN
Entrez ID		1716
HPRD ID		03273
Ensembl ID		ENSG00000114956
Uniprot IDs		D6W5I0 E5KSL5 E5KSL6 Q16854
PDB IDs		2OCP
Enriched GO Terms of Interacting Partners?		Neuron Apoptotic Process Neuron Death DNA Ligation Involved In DNA Recombination Cell Adhesion Synaptic Growth At Neuromuscular Junction Collateral Sprouting In Absence Of Injury Cell Development Collateral Sprouting Axon Midline Choice Point Recognition Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Lagging Strand Elongation Pro-B Cell Differentiation Axon Choice Point Recognition Establishment Of Integrated Proviral Latency Response To Oxidative Stress Response To Radiation Neuron Remodeling Immunoglobulin V(D)J Recombination Establishment Of Viral Latency T Cell Receptor V(D)J Recombination DNA Ligation Involved In DNA Repair Lymphoid Progenitor Cell Differentiation DNA Ligation Signal Complex Assembly Nucleotide-excision Repair, DNA Gap Filling Cellular Response To Lithium Ion Cellular Copper Ion Homeostasis Cell Activation Regulation Of Neurogenesis Cell Morphogenesis Involved In Differentiation Single Strand Break Repair Double-strand Break Repair Via Nonhomologous End Joining Copper Ion Homeostasis Suckling Behavior Negative Regulation Of Cell Differentiation Regulation Of Protein Kinase Activity Cell Differentiation Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Growth Hormone Receptor Signaling Pathway Response To Stress Regulation Of Kinase Activity Cellular Response To Growth Hormone Stimulus Isotype Switching V(D)J Recombination DNA Strand Elongation Involved In DNA Replication Neuron Maturation MRNA Polyadenylation Focal Adhesion Assembly Response To Lithium Ion Regulation Of Epidermal Growth Factor-activated Receptor Activity
Tagcloud ?		candidate center cholestasis clarify copy deoxyguanosine depletion failure hepatocerebral histopathologic infantile infants leukocytes liver manifested mitochondrial mpv17 muscle mutations pathogenic polymerase progressive radiologic referred representing sequenced skeletal suspected tertiary