TOM1L2 and RNF11

Number of citations of the paper that reports this interaction (PMID 15231748)
65

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		TOM1L2	RNF11
Gene Name		target of myb1-like 2 (chicken)	ring finger protein 11
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Intracellular Extracellular Vesicular Exosome	Ubiquitin Ligase Complex Nucleus Early Endosome Recycling Endosome Extracellular Vesicular Exosome
	Molecular Function	Protein Binding Protein Kinase Binding Clathrin Binding	DNA Binding Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding
	Biological Process	Intracellular Protein Transport Signal Transduction Negative Regulation Of Mitotic Nuclear Division	Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Protein Autoubiquitination
Pathways
Drugs
Diseases
GWAS			Ventricular conduction ( 21076409)
Protein-Protein Interactions		6 interactors: APP LAPTM5 MYO6 NEDD4 RNF11 UBC	68 interactors: AKT1 ANKRD13A APP ASCC2 AUP1 CALCOCO2 CBLB CCDC127 DCUN1D1 EPN1 EPN2 EPN3 EPS15 ERCC6 GGA1 GGA2 GGA3 HERC1 HERC2 HUWE1 IKBKG ITCH MYO6 NEDD4 NEDD4L OPTN PDCD6IP POLI PTPRC QARS RABGEF1 RIPK1 RNF168 RNF216 RPS27A SDCBP SMURF1 SMURF2 SNRNP70 SPRTN STAM2 STAMBP STAMBPL1 TAX1BP1 TNFAIP3 TNIP1 TOM1L2 UBA52 UBAC1 UBB UBC UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2E2 UBE2E3 UBE2N UBE2U UBQLN2 UBQLN4 USP5 WWP1 WWP2 ZFYVE16 ZFYVE9 ZNF350
Entrez ID		146691	26994
HPRD ID		18213	09955
Ensembl ID		ENSG00000175662	ENSG00000123091
Uniprot IDs		B7Z2L7 B7Z2U2 F5H3S6 Q6ZVM7	Q9Y3C5
PDB IDs
Enriched GO Terms of Interacting Partners?		Synapse Organization Intracellular Receptor Signaling Pathway Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Response To Abiotic Stimulus Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Neuromuscular Junction Development Regulation Of DNA-templated Transcription In Response To Stress Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Synapse Assembly DNA Damage Response, Signal Transduction By P53 Class Mediator Regulation Of ERBB Signaling Pathway Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Regulation Of Synapse Structure Or Activity Signal Transduction In Response To DNA Damage Intracellular Transport Proteolysis Involved In Cellular Protein Catabolic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter In Response To UV-induced DNA Damage Transmission Of Virus Development Involved In Symbiotic Interaction Cellular Protein Catabolic Process Protein Ubiquitination Negative Regulation Of Cellular Response To Growth Factor Stimulus Protein Modification By Small Protein Conjugation Protein Catabolic Process Signal Transduction By P53 Class Mediator Endocytosis Regulation Of Transcription From RNA Polymerase II Promoter Synaptic Growth At Neuromuscular Junction Notch Signaling Pathway Dendrite Development Establishment Of Localization In Cell Collateral Sprouting In Absence Of Injury Neuron Projection Development Protein Polyubiquitination Cellular Macromolecule Catabolic Process Regulation Of Cellular Response To Growth Factor Stimulus Collateral Sprouting Axon Midline Choice Point Recognition Neuron Development Positive Regulation Of Protein Catabolic Process Regulation Of Mitotic Cell Cycle Phase Transition Positive Regulation Of Cell Cycle Process Cellular Localization Regulation Of Cell Cycle Phase Transition Progesterone Receptor Signaling Pathway Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Locomotory Behavior Positive Regulation Of Transcription From RNA Polymerase II Promoter	Protein Ubiquitination Protein Polyubiquitination Protein Modification By Small Protein Conjugation Protein Catabolic Process Cellular Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Protein K48-linked Ubiquitination Cellular Macromolecule Catabolic Process Positive Regulation Of Protein Catabolic Process Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Activation Of Innate Immune Response Proteolysis Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Negative Regulation Of Signal Transduction Positive Regulation Of Innate Immune Response Regulation Of Protein Catabolic Process Nucleotide-binding Oligomerization Domain Containing Signaling Pathway Cellular Protein Modification Process Regulation Of Type I Interferon Production Toll-like Receptor Signaling Pathway Negative Regulation Of Signaling Toll-like Receptor 4 Signaling Pathway Protein K63-linked Ubiquitination Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Regulation Of Innate Immune Response TRIF-dependent Toll-like Receptor Signaling Pathway Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Catabolic Process Cellular Protein Metabolic Process Proteasomal Protein Catabolic Process MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Positive Regulation Of Protein Metabolic Process Negative Regulation Of Type I Interferon Production Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Immune Response-regulating Signaling Pathway Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Intracellular Transport Cellular Response To Stress Regulation Of DNA-templated Transcription In Response To Stress Transforming Growth Factor Beta Receptor Signaling Pathway Protein Metabolic Process Intracellular Protein Transport Negative Regulation Of Cellular Response To Growth Factor Stimulus Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Innate Immune Response Cellular Response To Stimulus
Tagcloud ?		becomes degradative endosomes enlarged fyn gat gga hepatocyte intermediary like1 like2 localizes multivesicular mvb mvbs myb1 p85 possesses ptap sorting stam tagged tsg101 ubiquitinated vhs vps27p
Tagcloud (Difference) ?		becomes degradative endosomes enlarged fyn gat gga hepatocyte intermediary like1 like2 localizes multivesicular mvb mvbs myb1 p85 possesses ptap sorting stam tagged tsg101 ubiquitinated vhs vps27p
Tagcloud (Intersection) ?