FAM9A and JMJD6

Number of citations of the paper that reports this interaction (PMID 23455924)
3

Data Source:
BioGRID (two hybrid)

		FAM9A	JMJD6
Gene Name		family with sequence similarity 9, member A	jumonji domain containing 6
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleolus	Nucleus Nucleoplasm Nucleolus Plasma Membrane
	Molecular Function	Protein Binding	RNA Binding Single-stranded RNA Binding Receptor Activity Iron Ion Binding Protein Binding Histone Demethylase Activity (H3-R2 Specific) Histone Demethylase Activity (H4-R3 Specific) Identical Protein Binding Peptidyl-lysine 5-dioxygenase Activity
	Biological Process		Kidney Development Sprouting Angiogenesis Transcription, DNA-templated Regulation Of Transcription, DNA-templated MRNA Processing Cell Surface Receptor Signaling Pathway Heart Development RNA Splicing Peptidyl-lysine Hydroxylation To 5-hydroxy-L-lysine Lung Development T Cell Differentiation In Thymus Macrophage Activation Recognition Of Apoptotic Cell Regulation Of MRNA Splicing, Via Spliceosome Erythrocyte Development Oxidation-reduction Process Retina Development In Camera-type Eye Histone H3-R2 Demethylation Histone H4-R3 Demethylation
Pathways
Drugs
Diseases
GWAS			Retinal arteriolar caliber ( 23776548)
Protein-Protein Interactions		5 interactors: JMJD6 KDM1A PRMT1 SETD8 ZDHHC17	28 interactors: AEBP2 ANKEF1 BRD4 C17orf97 CCNL1 CENPL DIP2A FAM9A FGD5 FRMD6 GNA14 HIST1H2BJ HMGXB4 LARP7 NAA50 NFIX NHP2 PRPF38A PSMC1 RSPO2 RSRC1 SLFN12 SLU7 STAC3 TAF1A U2AF1 ZCCHC17 ZNF451
Entrez ID		171482	23210
HPRD ID		06506	05371
Ensembl ID		ENSG00000183304	ENSG00000070495
Uniprot IDs		Q8IZU1	Q6NYC1
PDB IDs			3K2O 3LD8 3LDB
Enriched GO Terms of Interacting Partners?		Histone Modification Chromatin Modification Chromatin Organization Regulation Of Megakaryocyte Differentiation Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Regulation Of Hematopoietic Progenitor Cell Differentiation Chromosome Organization Histone Demethylation Protein Demethylation Regulation Of Signal Transduction By P53 Class Mediator Cellular Protein Modification Process Demethylation Histone H3-R2 Demethylation Histone H4-R3 Demethylation Regulation Of Primitive Erythrocyte Differentiation Peptidyl-lysine Hydroxylation To 5-hydroxy-L-lysine Cellular Protein Metabolic Process Histone Methylation Regulation Of Response To DNA Damage Stimulus Protein Methylation Regulation Of Myeloid Cell Differentiation Peptidyl-amino Acid Modification Protein Metabolic Process Negative Regulation Of Megakaryocyte Differentiation Myeloid Cell Differentiation Peptidyl-lysine Modification Peptidyl-lysine Monomethylation Peptidyl-arginine Methylation, To Asymmetrical-dimethyl Arginine Organelle Organization Negative Regulation Of Histone H3-K4 Methylation Histone H3-K9 Demethylation Recognition Of Apoptotic Cell Histone H3-K4 Demethylation Leukocyte Differentiation Negative Regulation Of Hematopoietic Progenitor Cell Differentiation Positive Regulation Of Megakaryocyte Differentiation Cellular Macromolecule Biosynthetic Process Positive Regulation Of Hormone Biosynthetic Process Macromolecule Biosynthetic Process Peptidyl-arginine N-methylation Negative Regulation Of Histone H3-K9 Methylation Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Negative Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Histone H4-R3 Methylation Methylation Negative Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Granulocyte Differentiation Phagocytosis, Recognition Regulation Of Intracellular Signal Transduction Histone Arginine Methylation	Chromatin Organization RNA Processing RNA Metabolic Process Gene Expression Chromosome Organization Alternative MRNA Splicing, Via Spliceosome Nucleosome Assembly Chromatin Modification Cellular Nitrogen Compound Metabolic Process Chromatin Assembly RNA Splicing Nucleosome Organization Chromatin Assembly Or Disassembly G1/S Transition Of Mitotic Cell Cycle Nucleobase-containing Compound Metabolic Process Protein-DNA Complex Assembly Mitotic Cell Cycle MRNA Processing Chromatin Remodeling DNA Packaging Nitrogen Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Mitotic Sister Chromatid Cohesion, Centromeric RRNA Pseudouridine Synthesis Histone H4 Acetylation MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions MRNA Metabolic Process Regulation Of Phosphorylation Of RNA Polymerase II C-terminal Domain Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition DNA-templated Transcription, Termination Negative Regulation Of Gene Expression, Epigenetic DNA Conformation Change Regulation Of Wnt Signaling Pathway Cellular Macromolecular Complex Assembly Negative Regulation Of DNA Damage Checkpoint Apical Constriction Lung Growth Histone H3-K14 Acetylation Mitotic Cell Cycle Process MRNA 3'-splice Site Recognition Transcription, DNA-templated Histone Acetylation Trachea Cartilage Morphogenesis Internal Peptidyl-lysine Acetylation Positive Regulation Of Canonical Wnt Signaling Pathway Peptidyl-lysine Acetylation Internal Protein Amino Acid Acetylation
Tagcloud ?		aberrantly aberration ap1s2 brcc3 cpxcr1 cxorf45 ddx53 dmd fhl1 gabre gjb1 hdac8 hypermethylated hypomethylated hypomethylation hysterectomy irreversible leiomyoma leiomyomas myometrium nxf5 paired pcdh11x ream taf1 tag uterine vbp1 xist	acinus arginine auxiliary bona definition exerts exon fide hydroxylate localises luc7 luc7l3 modifies modulator modulatory nascent oxoglutarate oxygenase plasmid punctually reporter rs splice splicing sr srsf1 srsf11 u2 u2af65
Tagcloud (Difference) ?		aberrantly aberration ap1s2 brcc3 cpxcr1 cxorf45 ddx53 dmd fhl1 gabre gjb1 hdac8 hypermethylated hypomethylated hypomethylation hysterectomy irreversible leiomyoma leiomyomas myometrium nxf5 paired pcdh11x ream taf1 tag uterine vbp1 xist	acinus arginine auxiliary bona definition exerts exon fide hydroxylate localises luc7 luc7l3 modifies modulator modulatory nascent oxoglutarate oxygenase plasmid punctually reporter rs splice splicing sr srsf1 srsf11 u2 u2af65
Tagcloud (Intersection) ?