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DES and TRIM7
Number of citations of the paper that reports this interaction (PubMedID
11916970
)
0
Data Source:
HPRD
(two hybrid)
DES
TRIM7
Description
desmin
tripartite motif containing 7
Image
No pdb structure
GO Annotations
Cellular Component
Nucleus
Nuclear Envelope
Cytoplasm
Cytosol
Cytoskeleton
Intermediate Filament
Plasma Membrane
Cell-cell Junction
Fascia Adherens
Intercalated Disc
Membrane
Z Disc
Neuromuscular Junction
Sarcolemma
Contractile Muscle Fiber
Intermediate Filament Cytoskeleton
Cell Tip
Extracellular Exosome
Cardiac Myofibril
Supramolecular Fiber
Nucleus
Cytoplasm
Golgi Apparatus
Molecular Function
Structural Constituent Of Cytoskeleton
Protein Binding
Cytoskeletal Protein Binding
Identical Protein Binding
Protein Binding
Zinc Ion Binding
Transferase Activity
Metal Ion Binding
Ubiquitin Protein Ligase Activity
Biological Process
Muscle Contraction
Nuclear Envelope Organization
Cytoskeleton Organization
Regulation Of Heart Contraction
Intermediate Filament Organization
Skeletal Muscle Organ Development
Protein Ubiquitination
Innate Immune Response
Defense Response To Virus
Antiviral Innate Immune Response
Pathways
Striated Muscle Contraction
Drugs
Diseases
Myofibrillar myopathies (MFM), including: Desminopathy (MFM1); alpha-B Crystallinopathy (MFM2); Myotilinopathy (MFM3); Zaspopathy (MFM4); Filaminopathy (MFM5); Bag3opathy
Dilated cardiomyopathy (DCM)
Distal muscular dystrophies, including: Welander distal myopathy (WDM); Tibial muscular dystrophy (TMD); Nonaka distal myopathy with rimmed vacuoles (DMRV); Miyoshi myopathy (MM); Laing myopathy (MPD1); Distal nebulin myopathy (DNM); Distal desminopathy (MFM1); alpha-B Crystallinopathy (MFM2); Distal myotilinopathy (MFM3); Distal zaspopathy (MFM4); Distal myopathy 3 (MPD2, VCPDM)
Scapuloperoneal myopathy (SPM)
GWAS
Electrocardiogram morphology (amplitude at temporal datapoints) (
32916098
)
Resting heart rate (
27798624
)
Interacting Genes
58 interacting genes:
AURKB
BAG5
BRCA1
C1orf216
CAPN1
CDC73
CLIP4
CRYAB
CT55
CWF19L2
DDX6
DSP
DUX1
DUX4
EHHADH
ENO1
GOLGA6L9
HSPB1
ITSN1
KRT13
KRT15
KRT20
KRT33B
KRT37
LBX1
LENG1
LMO4
LONRF3
M1AP
MAPKAPK2
NEB
NEFL
NEK6
PIAS2
PIH1D2
PKD1
PLEKHA5
POLR2G
PPL
PPP1R18
PRPH
RNF4
ROCK1
S100A1
S100B
SHBG
SNAPIN
SPTAN1
SYNC
SYNM
TCEA2
TFIP11
TRIM55
TRIM63
TRIM7
UBE2I
YES1
ZMYM5
30 interacting genes:
AQP1
ATG7
BCAM
CDK13
CFL2
CRYGC
CTNNAL1
DES
GTF2A2
GYG1
IRAK4
MAD2L2
NAA35
NABP1
OTUD6A
RAB2A
RIN1
RNASE1
RNF187
RSPH14
SIAH1
SRC
TP53I13
TRMT10A
UBE2D1
UBE2D2
UBE2D3
UBE2E1
UBE2N
UBE2W
Entrez ID
1674
81786
HPRD ID
00514
11648
Ensembl ID
ENSG00000175084
ENSG00000146054
Uniprot IDs
P17661
Q53SB5
Q9C029
PDB IDs
6UMA
6UMB
7OVX
7OW2
7W0Q
7W0S
7W0T
7X6Y
7X6Z
7X70
7Y3A
7Y3B
7Y3C
8A5L
8A5M
8A8X
8R5B
8R5C
8R5D
9HIN
Enriched GO Terms of Interacting Partners
?
Intermediate Filament-based Process
Intermediate Filament Cytoskeleton Organization
Intermediate Filament
Intermediate Filament Organization
Structural Constituent Of Cytoskeleton
Structural Molecule Activity
Contractile Muscle Fiber
Cytoskeleton Organization
M Band
Cytoskeleton
Structural Constituent Of Skin Epidermis
Protein Binding
Z Disc
Supramolecular Fiber Organization
Keratin Filament
Cytoplasm
Intermediate Filament Cytoskeleton
Cornified Envelope
Tissue Morphogenesis
Organelle Organization
Morphogenesis Of An Epithelium
Extracellular Exosome
Anterograde Axonal Transport
Ubiquitin Conjugating Enzyme Activity
Ubiquitin-protein Transferase Activity
Post-translational Protein Modification
Modification-dependent Protein Catabolic Process
Ubiquitin-dependent Protein Catabolic Process
Protein Polyubiquitination
Protein K48-linked Ubiquitination
Proteolysis Involved In Protein Catabolic Process
Protein Modification By Small Protein Conjugation
Transferase Activity
Protein Monoubiquitination
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
TORC1 Signaling
Negative Regulation Of TORC1 Signaling
Protein Ubiquitination
TOR Signaling
Proteasomal Protein Catabolic Process
Negative Regulation Of TOR Signaling
Proteolysis
Regulation Of TORC1 Signaling
Macromolecule Catabolic Process
Protein Modification Process
Cytosol
Protein Catabolic Process
Cellular Response To Nutrient Levels
Regulation Of TOR Signaling
Catabolic Process
Protein Autoubiquitination
Nucleus
Ubiquitin Protein Ligase Activity
Extracellular Exosome
ATP Binding
Positive Regulation Of Protein Modification Process
Positive Regulation Of Protein Polyubiquitination
Nucleotide Binding
Intracellular Signal Transduction
Protein Binding
Endolysosomal Toll-like Receptor Signaling Pathway
Macromolecule Metabolic Process
Ephrin Receptor Binding
Regulation Of Protein Polyubiquitination
Ficolin-1-rich Granule Lumen
Metanephric Descending Thin Limb Development
Metanephric Proximal Straight Tubule Development
Nitric Oxide Transmembrane Transporter Activity
Metanephric Proximal Convoluted Tubule Segment 2 Development
Supramolecular Fiber Organization
Defense Response To Virus
Response To Nutrient Levels
Postreplication Repair
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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