TRIM7 and RSPH14

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		TRIM7	RSPH14
Description		tripartite motif containing 7	radial spoke head 14 homolog
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GO Annotations	Cellular Component	Nucleus Cytoplasm Golgi Apparatus	Radial Spoke Cytoplasm Cytoskeleton Cilium Motile Cilium Cell Projection
	Molecular Function	Protein Binding Zinc Ion Binding Transferase Activity Metal Ion Binding Ubiquitin Protein Ligase Activity	Protein Binding
	Biological Process	Protein Ubiquitination Innate Immune Response Defense Response To Virus Antiviral Innate Immune Response
Pathways
Drugs
Diseases
GWAS			Serum parathyroid hormone levels ( 27927781)
Interacting Genes		30 interacting genes: AQP1 ATG7 BCAM CDK13 CFL2 CRYGC CTNNAL1 DES GTF2A2 GYG1 IRAK4 MAD2L2 NAA35 NABP1 OTUD6A RAB2A RIN1 RNASE1 RNF187 RSPH14 SIAH1 SRC TP53I13 TRMT10A UBE2D1 UBE2D2 UBE2D3 UBE2E1 UBE2N UBE2W	40 interacting genes: ABI2 AGAP1 ALS2CL AP1M1 AP2M1 BPIFA1 CCDC102B CDR2 CNTROB COG6 EPS8 FHL3 GABPB1 GOLGA2 JUP KASH5 KIFC3 KRT15 KRT31 KRT40 KRT75 KRT76 LZTS1 MNS1 PIBF1 POLR1C REL RPH3AL RSPH3 SEPTIN12 SMAD4 TCF4 TRAF2 TRIM27 TRIM50 TRIM69 TRIM7 VPS9D1 ZNF474 ZNF629
Entrez ID		81786	27156
HPRD ID		11648	16136
Ensembl ID		ENSG00000146054	ENSG00000100218
Uniprot IDs		Q9C029	Q9UHP6
PDB IDs		6UMA 6UMB 7OVX 7OW2 7W0Q 7W0S 7W0T 7X6Y 7X6Z 7X70 7Y3A 7Y3B 7Y3C 8A5L 8A5M 8A8X 8R5B 8R5C 8R5D 9HIN	8J07
Enriched GO Terms of Interacting Partners?		Ubiquitin Conjugating Enzyme Activity Ubiquitin-protein Transferase Activity Post-translational Protein Modification Modification-dependent Protein Catabolic Process Ubiquitin-dependent Protein Catabolic Process Protein Polyubiquitination Protein K48-linked Ubiquitination Proteolysis Involved In Protein Catabolic Process Protein Modification By Small Protein Conjugation Transferase Activity Protein Monoubiquitination Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process TORC1 Signaling Negative Regulation Of TORC1 Signaling Protein Ubiquitination TOR Signaling Proteasomal Protein Catabolic Process Negative Regulation Of TOR Signaling Proteolysis Regulation Of TORC1 Signaling Macromolecule Catabolic Process Protein Modification Process Cytosol Protein Catabolic Process Cellular Response To Nutrient Levels Regulation Of TOR Signaling Catabolic Process Protein Autoubiquitination Nucleus Ubiquitin Protein Ligase Activity Extracellular Exosome ATP Binding Positive Regulation Of Protein Modification Process Positive Regulation Of Protein Polyubiquitination Nucleotide Binding Intracellular Signal Transduction Protein Binding Endolysosomal Toll-like Receptor Signaling Pathway Macromolecule Metabolic Process Ephrin Receptor Binding Regulation Of Protein Polyubiquitination Ficolin-1-rich Granule Lumen Metanephric Descending Thin Limb Development Metanephric Proximal Straight Tubule Development Nitric Oxide Transmembrane Transporter Activity Metanephric Proximal Convoluted Tubule Segment 2 Development Supramolecular Fiber Organization Defense Response To Virus Response To Nutrient Levels Postreplication Repair	Intermediate Filament Structural Constituent Of Skin Epidermis Intermediate Filament Organization Cytoskeleton Organization Supramolecular Fiber Organization Cytoskeleton Intermediate Filament Cytoskeleton Organization Keratin Filament Intermediate Filament-based Process Organelle Organization Structural Molecule Activity Protein Binding Identical Protein Binding Zonula Adherens Sebaceous Gland Development Clathrin Adaptor Complex Centrosome Separation Positive Regulation Of Actin Nucleation Small GTPase Binding Innate Immune Response Epithelial Cell-cell Adhesion Clathrin Adaptor Activity
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