DES and CT55

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		DES	CT55
Description		desmin	cancer/testis antigen 55
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nuclear Envelope Cytoplasm Cytosol Cytoskeleton Intermediate Filament Plasma Membrane Cell-cell Junction Fascia Adherens Intercalated Disc Membrane Z Disc Neuromuscular Junction Sarcolemma Contractile Muscle Fiber Intermediate Filament Cytoskeleton Cell Tip Extracellular Exosome Cardiac Myofibril Supramolecular Fiber	Acrosomal Vesicle Cytoplasm Cilium Cytoplasmic Vesicle Motile Cilium Sperm Flagellum Cell Projection
	Molecular Function	Structural Constituent Of Cytoskeleton Protein Binding Cytoskeletal Protein Binding Identical Protein Binding	Protein Binding
	Biological Process	Muscle Contraction Nuclear Envelope Organization Cytoskeleton Organization Regulation Of Heart Contraction Intermediate Filament Organization Skeletal Muscle Organ Development	Spermatogenesis
Pathways		Striated Muscle Contraction
Drugs
Diseases		Myofibrillar myopathies (MFM), including: Desminopathy (MFM1); alpha-B Crystallinopathy (MFM2); Myotilinopathy (MFM3); Zaspopathy (MFM4); Filaminopathy (MFM5); Bag3opathy Dilated cardiomyopathy (DCM) Distal muscular dystrophies, including: Welander distal myopathy (WDM); Tibial muscular dystrophy (TMD); Nonaka distal myopathy with rimmed vacuoles (DMRV); Miyoshi myopathy (MM); Laing myopathy (MPD1); Distal nebulin myopathy (DNM); Distal desminopathy (MFM1); alpha-B Crystallinopathy (MFM2); Distal myotilinopathy (MFM3); Distal zaspopathy (MFM4); Distal myopathy 3 (MPD2, VCPDM) Scapuloperoneal myopathy (SPM)
GWAS		Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Resting heart rate ( 27798624)
Interacting Genes		58 interacting genes: AURKB BAG5 BRCA1 C1orf216 CAPN1 CDC73 CLIP4 CRYAB CT55 CWF19L2 DDX6 DSP DUX1 DUX4 EHHADH ENO1 GOLGA6L9 HSPB1 ITSN1 KRT13 KRT15 KRT20 KRT33B KRT37 LBX1 LENG1 LMO4 LONRF3 M1AP MAPKAPK2 NEB NEFL NEK6 PIAS2 PIH1D2 PKD1 PLEKHA5 POLR2G PPL PPP1R18 PRPH RNF4 ROCK1 S100A1 S100B SHBG SNAPIN SPTAN1 SYNC SYNM TCEA2 TFIP11 TRIM55 TRIM63 TRIM7 UBE2I YES1 ZMYM5	32 interacting genes: AIRIM BFSP2 CABP5 CATSPERT CPNE2 DES EXOC7 FAAP20 GFAP GPRASP3 KIAA0753 KLC3 KLHL42 KYNU LYPLAL1 MBD3 MEMO1 MEOX2 P4HA3 PAX7 PIH1D2 PRPH SAMD11 SHC3 SNF8 SPG21 TFIP11 TLE5 TXLNB VIM ZNF177 ZNF559-ZNF177
Entrez ID		1674	54967
HPRD ID		00514	06534
Ensembl ID		ENSG00000175084	ENSG00000169551
Uniprot IDs		P17661 Q53SB5	Q8WUE5
PDB IDs
Enriched GO Terms of Interacting Partners?		Intermediate Filament-based Process Intermediate Filament Cytoskeleton Organization Intermediate Filament Intermediate Filament Organization Structural Constituent Of Cytoskeleton Structural Molecule Activity Contractile Muscle Fiber Cytoskeleton Organization M Band Cytoskeleton Structural Constituent Of Skin Epidermis Protein Binding Z Disc Supramolecular Fiber Organization Keratin Filament Cytoplasm Intermediate Filament Cytoskeleton Cornified Envelope Tissue Morphogenesis Organelle Organization Morphogenesis Of An Epithelium Extracellular Exosome Anterograde Axonal Transport	Intermediate Filament Organization Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Structural Constituent Of Cytoskeleton Intermediate Filament Intermediate Filament Cytoskeleton Lens Fiber Cell Development Bergmann Glial Cell Differentiation Protein Binding Astrocyte Development
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