TRIM7 and RAB2A

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		TRIM7	RAB2A
Description		tripartite motif containing 7	RAB2A, member RAS oncogene family
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GO Annotations	Cellular Component	Nucleus Cytoplasm Golgi Apparatus	Golgi Membrane Autophagosome Membrane Acrosomal Vesicle Nucleus Cytoplasm Lysosomal Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Cytosol Membrane Cytoplasmic Vesicle Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Melanosome Extracellular Exosome
	Molecular Function	Protein Binding Zinc Ion Binding Transferase Activity Metal Ion Binding Ubiquitin Protein Ligase Activity	Nucleotide Binding GTPase Activity G Protein Activity Protein Binding GTP Binding Hydrolase Activity GDP Binding Metal Ion Binding
	Biological Process	Protein Ubiquitination Innate Immune Response Defense Response To Virus Antiviral Innate Immune Response	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Golgi Organization Protein Transport Vesicle-mediated Transport Macroautophagy Autophagosome-lysosome Fusion
Pathways			Golgi Cisternae Pericentriolar Stack Reorganization RAB geranylgeranylation
Drugs
Diseases
GWAS			Aspartate aminotransferase levels ( 33547301) Autoimmune thyroid disease ( 32581359) Estimated glomerular filtration rate ( 31152163) Low density lipoprotein cholesterol levels ( 32154731) Neutrophil count ( 32888494) Systemic sclerosis ( 31672989) Total cholesterol levels ( 29083408)
Interacting Genes		30 interacting genes: AQP1 ATG7 BCAM CDK13 CFL2 CRYGC CTNNAL1 DES GTF2A2 GYG1 IRAK4 MAD2L2 NAA35 NABP1 OTUD6A RAB2A RIN1 RNASE1 RNF187 RSPH14 SIAH1 SRC TP53I13 TRMT10A UBE2D1 UBE2D2 UBE2D3 UBE2E1 UBE2N UBE2W	29 interacting genes: BLZF1 CBFB CCDC125 CEBPA CFL2 FAM114A1 FAM114A2 FRMD1 GAA GAPDH GARIN4 GARIN6 GDI2 GOLGA2 GORASP2 HES6 ICA1 MAPK6 MAPKAPK3 OTOS PMAIP1 PRKCI RBSN RGS2 SGSM2 STAMBPL1 TBC1D25 TMEM70 TRIM7
Entrez ID		81786	5862
HPRD ID		11648	01539
Ensembl ID		ENSG00000146054	ENSG00000104388
Uniprot IDs		Q9C029	P61019
PDB IDs		6UMA 6UMB 7OVX 7OW2 7W0Q 7W0S 7W0T 7X6Y 7X6Z 7X70 7Y3A 7Y3B 7Y3C 8A5L 8A5M 8A8X 8R5B 8R5C 8R5D 9HIN	1Z0A
Enriched GO Terms of Interacting Partners?		Ubiquitin Conjugating Enzyme Activity Ubiquitin-protein Transferase Activity Post-translational Protein Modification Modification-dependent Protein Catabolic Process Ubiquitin-dependent Protein Catabolic Process Protein Polyubiquitination Protein K48-linked Ubiquitination Proteolysis Involved In Protein Catabolic Process Protein Modification By Small Protein Conjugation Transferase Activity Protein Monoubiquitination Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process TORC1 Signaling Negative Regulation Of TORC1 Signaling Protein Ubiquitination TOR Signaling Proteasomal Protein Catabolic Process Negative Regulation Of TOR Signaling Proteolysis Regulation Of TORC1 Signaling Macromolecule Catabolic Process Protein Modification Process Cytosol Protein Catabolic Process Cellular Response To Nutrient Levels Regulation Of TOR Signaling Catabolic Process Protein Autoubiquitination Nucleus Ubiquitin Protein Ligase Activity Extracellular Exosome ATP Binding Positive Regulation Of Protein Modification Process Positive Regulation Of Protein Polyubiquitination Nucleotide Binding Intracellular Signal Transduction Protein Binding Endolysosomal Toll-like Receptor Signaling Pathway Macromolecule Metabolic Process Ephrin Receptor Binding Regulation Of Protein Polyubiquitination Ficolin-1-rich Granule Lumen Metanephric Descending Thin Limb Development Metanephric Proximal Straight Tubule Development Nitric Oxide Transmembrane Transporter Activity Metanephric Proximal Convoluted Tubule Segment 2 Development Supramolecular Fiber Organization Defense Response To Virus Response To Nutrient Levels Postreplication Repair
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