DAB1 and USP53

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		DAB1	USP53
Gene Name		Dab, reelin signal transducer, homolog 1 (Drosophila)	ubiquitin specific peptidase 53
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytosol Brush Border Postsynaptic Density Membrane Neuron Projection Neuronal Cell Body Apical Part Of Cell Perinuclear Region Of Cytoplasm	Cellular_component
	Molecular Function	Phosphatidylinositol 3-kinase Binding
	Biological Process	Negative Regulation Of Cell Adhesion Small GTPase Mediated Signal Transduction Midgut Development Adult Walking Behavior Dendrite Development Ventral Spinal Cord Development Cerebellum Structural Organization Cerebral Cortex Radially Oriented Cell Migration Cell-cell Adhesion Involved In Neuronal-glial Interactions Involved In Cerebral Cortex Radial Glia Guided Migration Radial Glia Guided Migration Of Purkinje Cell Response To Drug Positive Regulation Of Neuron Differentiation Positive Regulation Of Protein Kinase Activity Negative Regulation Of JAK-STAT Cascade Negative Regulation Of Astrocyte Differentiation Negative Regulation Of Axonogenesis Golgi Localization Lateral Motor Column Neuron Migration	Ubiquitin-dependent Protein Catabolic Process Biological_process
Pathways
Drugs
Diseases
GWAS		Bulimia nervosa ( 23568457) Immune reponse to smallpox (secreted IL-10) ( 22610502) Kawasaki disease ( 21221998) Pubertal anthropometrics ( 23449627)
Protein-Protein Interactions		73 interactors: APLP1 APLP2 APP ARID5A BHLHE40 C1orf94 CDK5 CDK6 CIART CLASRP CRK CRKL DAB2IP DAZAP2 ERBB2 ERBB3 FAM103A1 FAM168A HMBOX1 HNRNPLL HYAL3 INPP5D ITGB2 ITGB3 ITGB5 ITGB7 KRTAP19-5 KRTAP19-7 KRTAP8-1 LDLR LGALS9B LGALS9C LNX1 LRP1 LRP2 LRP8 MAGED1 MBNL1 MBNL3 MYO6 NAF1 PAFAH1B1 PCDH18 PIN1 PLCG1 POGZ PPIG PRR20A PTPN11 RBFOX1 RBFOX2 RELN RHOXF2 ROR2 SERF2 SIAH1 SIRPB1 SMAP2 SNRPB SRC STRBP TCEA2 TCEANC TMTC3 TOLLIP USP53 VENTX VLDLR WDYHV1 ZBTB32 ZC3H10 ZCCHC10 ZNF488	5 interactors: DAB1 GRB2 IREB2 PVRL2 TRAF2
Entrez ID		1600	54532
HPRD ID		04582	11669
Ensembl ID		ENSG00000173406	ENSG00000145390
Uniprot IDs		O75553	Q70EK8 Q9H9I0
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Metabolic Process Multicellular Organismal Development Regulation Of Phosphorus Metabolic Process Positive Regulation Of Transferase Activity Positive Regulation Of Protein Kinase Activity Positive Regulation Of Kinase Activity Regulation Of Protein Kinase Activity Regulation Of Phosphorylation Reelin-mediated Signaling Pathway Positive Regulation Of Protein Modification Process Developmental Process Regulation Of Kinase Activity Regulation Of Protein Phosphorylation Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Cellular Protein Metabolic Process Central Nervous System Development Positive Regulation Of Protein Phosphorylation Anatomical Structure Development Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Protein Metabolic Process Regulation Of Gene Expression Positive Regulation Of Phosphorylation Positive Regulation Of Metabolic Process Nervous System Development Brain Development Regulation Of Cellular Protein Metabolic Process Gliogenesis Regulation Of Protein Metabolic Process Head Development Anatomical Structure Morphogenesis Response To External Stimulus Cell Surface Receptor Signaling Pathway Forebrain Development System Development Cell Differentiation Movement Of Cell Or Subcellular Component Negative Regulation Of Cellular Metabolic Process Organ Development Wound Healing Immune System Process Layer Formation In Cerebral Cortex Locomotion Neuron Projection Morphogenesis Regulation Of RNA Metabolic Process Neurotrophin TRK Receptor Signaling Pathway Signaling Endocytosis MRNA Processing Neurogenesis Cerebral Cortex Radial Glia Guided Migration	Positive Regulation Of Cell Activation Regulation Of Cell Activation Regulation Of Cell Adhesion Positive Regulation Of Immune Response Positive Regulation Of T Cell Mediated Immunity Cell-cell Adhesion Involved In Neuronal-glial Interactions Involved In Cerebral Cortex Radial Glia Guided Migration Coreceptor-mediated Virion Attachment To Host Cell Protein Heterooligomerization Positive Regulation Of Adaptive Immune Response Susceptibility To T Cell Mediated Cytotoxicity Sperm Mitochondrion Organization Cerebellum Structural Organization Regulation Of Immune Response Positive Regulation Of Immune System Process Positive Regulation Of Innate Immune Response Lateral Motor Column Neuron Migration Fusion Of Virus Membrane With Host Plasma Membrane Regulation Of Adaptive Immune Response Positive Regulation Of T Cell Activation Spinal Cord Motor Neuron Migration Positive Regulation Of Homotypic Cell-cell Adhesion Radial Glia Guided Migration Of Purkinje Cell Response To Iron(II) Ion Susceptibility To Natural Killer Cell Mediated Cytotoxicity Cell-cell Adhesion Via Plasma-membrane Adhesion Molecules Cell-cell Adhesion Positive Regulation Of Cell-cell Adhesion Regulation Of Innate Immune Response Cell Projection Organization Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity Directed Against Tumor Cell Target Negative Regulation Of Glial Cell Apoptotic Process Locomotion Regulation Of T Cell Activation Regulation Of Immune System Process Regulation Of Phosphorylation Virion Attachment To Host Cell Positive Regulation Of Immune Response To Tumor Cell Protoporphyrinogen IX Biosynthetic Process Cellular Response To Stimulus Aging Adhesion Of Symbiont To Host Cell Differentiation Positive Regulation Of Protein Homodimerization Activity Branching Involved In Labyrinthine Layer Morphogenesis Regulation Of Phosphorus Metabolic Process Cellular Response To Nitric Oxide Protoporphyrinogen IX Metabolic Process Regulation Of Cell-cell Adhesion Positive Regulation Of Cell Adhesion Cellular Response To Stress
Tagcloud ?		assist cajal connections cortical d1x dieker disabled doublecortn dubbed dysplasias hydrolase instructs lis1 lissencephaly malformation marginal miller neuregulin neurotrophic neurotrophin p35 plate preplate radial reelin retzius tangential tbr thalamocortical
Tagcloud (Difference) ?		assist cajal connections cortical d1x dieker disabled doublecortn dubbed dysplasias hydrolase instructs lis1 lissencephaly malformation marginal miller neuregulin neurotrophic neurotrophin p35 plate preplate radial reelin retzius tangential tbr thalamocortical
Tagcloud (Intersection) ?