SNRNP48 and UTP14A

Number of citations of the paper that reports this interaction (PubMedID 34133714)
84

Data Source:
BioGRID (two hybrid)

		SNRNP48	UTP14A
Description		small nuclear ribonucleoprotein U11/U12 subunit 48	UTP14A small subunit processome component
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Spliceosomal Complex U12-type Spliceosomal Complex Cytosol	Nucleus Nucleoplasm Nucleolus Cytosol Small-subunit Processome
	Molecular Function	Protein Binding Zinc Ion Binding Metal Ion Binding	RNA Binding Protein Binding
	Biological Process	MRNA Processing RNA Splicing	RRNA Processing Ribosome Biogenesis
Pathways		mRNA Splicing - Minor Pathway	rRNA modification in the nucleus and cytosol Major pathway of rRNA processing in the nucleolus and cytosol
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Diseases
GWAS		BMI x environmental factors (excluding physical activity) interaction ( 33654129) BMI x environmental factors (including physical activity) interaction ( 33654129) Height ( 31562340) Obesity-related traits ( 23251661)
Interacting Genes		14 interacting genes: CDCA7L ENKD1 EXOSC7 GPX4 GRN HUNK LUC7L2 MRPS27 PRPF6 SRSF8 SUPT5H TFIP11 UBASH3A UTP14A	54 interacting genes: AKTIP APLP1 APP ARIH2 AXIN1 BICD2 CCDC106 CCDC85B CEP70 CPE CSNK2A1 CSNK2B DLEU1 EXOSC8 GADD45G HNRNPH3 HOOK1 HOOK2 HTT KRT31 LAMTOR5 LDOC1 LMO1 LSM3 NIN NINL PDCD5 PDZK1IP1 PHF10 PRKCZ PSG1 PTEN PTPRS RABIF RGS1 RHOH RNF10 RPA2 RSRC1 SAT1 SMYD1 SNRNP48 SSR1 TERF1 TFIP11 TINAGL1 TP53 TP53BP2 TRDMT1 TXLNB USO1 VIM WDR33 ZNF24
Entrez ID		154007	10813
HPRD ID		12858	06712
Ensembl ID		ENSG00000168566	ENSG00000156697
Uniprot IDs		Q6IEG0	Q9BVJ6
PDB IDs		2VY4 2VY5 8R7N 8Y6O 9GBW 9GC0 9GCL	7MQ8 7MQ9 7MQA 7WTS
Enriched GO Terms of Interacting Partners?		RNA Binding Nuclear Speck	FHF Complex Protein Localization To Perinuclear Region Of Cytoplasm Microtubule Cytoskeleton Organization Microtubule Anchoring At Microtubule Organizing Center HOPS Complex MRNA Metabolic Process Identical Protein Binding Protein Kinase CK2 Complex Symbiont-mediated Disruption Of Host Cell PML Body PML Body Cellular Response To Norepinephrine Stimulus Response To Norepinephrine Cellular Localization Organelle Organization Microtubule Anchoring Early Endosome To Late Endosome Transport P53 Binding Dynein Light Intermediate Chain Binding Apoptotic Process Positive Regulation Of Aggrephagy Central Nervous System Development Cytoplasm Programmed Cell Death Cell Death Positive Regulation Of Excitatory Postsynaptic Potential Fibrillar Center Microtubule-based Process Cytoskeleton Organization Microtubule Organizing Center Intracellular Transport Nucleus Cytoskeleton-dependent Intracellular Transport G-rich Strand Telomeric DNA Binding Cellular Response To Muramyl Dipeptide Modulation Of Excitatory Postsynaptic Potential Developmental Cell Growth Microtubule Anchoring At Centrosome Regulation Of Nervous System Process Endosome To Lysosome Transport Nuclear Matrix Supramolecular Fiber Organization Negative Regulation Of DNA Metabolic Process Negative Regulation Of Cell Cycle Negative Regulation Of Neurogenesis Centrosome Nucleoplasm Dynactin Binding Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle Negative Regulation Of Nervous System Development Cytoplasmic Microtubule Organization
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