SNRNP48 and MRPS27

Number of citations of the paper that reports this interaction (PubMedID 34133714)
84

Data Source:
BioGRID (two hybrid)

		SNRNP48	MRPS27
Description		small nuclear ribonucleoprotein U11/U12 subunit 48	mitochondrial ribosomal protein S27
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Spliceosomal Complex U12-type Spliceosomal Complex Cytosol	Nucleolus Cytoplasm Mitochondrion Mitochondrial Inner Membrane Mitochondrial Small Ribosomal Subunit Ribosome Ribonucleoprotein Complex
	Molecular Function	Protein Binding Zinc Ion Binding Metal Ion Binding	TRNA Binding RNA Binding Protein Binding RRNA Binding
	Biological Process	MRNA Processing RNA Splicing	Regulation Of Translation Cell Population Proliferation Mitochondrial Translation
Pathways		mRNA Splicing - Minor Pathway	Mitochondrial translation initiation Mitochondrial translation elongation Mitochondrial translation elongation Mitochondrial translation termination Mitochondrial ribosome-associated quality control
Drugs
Diseases
GWAS		BMI x environmental factors (excluding physical activity) interaction ( 33654129) BMI x environmental factors (including physical activity) interaction ( 33654129) Height ( 31562340) Obesity-related traits ( 23251661)	Refractive error ( 32231278)
Interacting Genes		14 interacting genes: CDCA7L ENKD1 EXOSC7 GPX4 GRN HUNK LUC7L2 MRPS27 PRPF6 SRSF8 SUPT5H TFIP11 UBASH3A UTP14A	5 interacting genes: CFTR NECAB2 PTEN SNRNP48 YWHAQ
Entrez ID		154007	23107
HPRD ID		12858	17596
Ensembl ID		ENSG00000168566	ENSG00000113048
Uniprot IDs		Q6IEG0	G5EA06 Q6PKB3 Q92552
PDB IDs		2VY4 2VY5 8R7N 8Y6O 9GBW 9GC0 9GCL	3J9M 6NU2 6NU3 6RW4 6RW5 6VLZ 6VMI 6ZM5 6ZM6 6ZS9 6ZSA 6ZSB 6ZSC 6ZSD 6ZSE 6ZSG 7A5F 7A5G 7A5I 7A5K 7L08 7OG4 7P2E 7PNX 7PNY 7PNZ 7PO0 7PO1 7PO2 7PO3 7QI4 7QI5 7QI6 8ANY 8CSP 8CSQ 8CSR 8CSS 8CST 8CSU 8K2A 8OIR 8OIS 8QRK 8QRL 8QRM 8QRN 8RRI 8XT0 8XT2
Enriched GO Terms of Interacting Partners?		RNA Binding Nuclear Speck	Negative Regulation Of Transport 14-3-3 Protein Binding Regulation Of Transport Positive Regulation Of Anion Channel Activity Intracellularly ATP-gated Chloride Channel Activity Positive Regulation Of Voltage-gated Chloride Channel Activity Sec61 Translocon Complex Binding PDZ Domain Binding Negative Regulation Of Synaptic Vesicle Clustering Phosphatidylinositol-3,4-bisphosphate 3-phosphatase Activity Negative Regulation Of Keratinocyte Migration Inositol-1,3,4,5-tetrakisphosphate 3-phosphatase Activity Synapse Inositol-1,3,4,5,6-pentakisphosphate 3-phosphatase Activity Somatostatin Secretion Positive Regulation Of Epinephrine Secretion Negative Regulation Of G Protein-coupled Receptor Internalization Positive Regulation Of Monoatomic Anion Transport Central Nervous System Myelin Maintenance Circadian Rhythm Rhythmic Synaptic Transmission Regulation Of Nervous System Process Negative Regulation Of Glucagon Secretion Positive Regulation Of Adenosine Receptor Signaling Pathway A2A Adenosine Receptor Binding Positive Regulation Of Enamel Mineralization Adult Behavior Negative Regulation Of Wound Healing, Spreading Of Epidermal Cells Type 5 Metabotropic Glutamate Receptor Binding Regulation Of Insulin Secretion Transepithelial Water Transport Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase Activity Myelin Sheath Adaxonal Region Phosphatidylinositol Phosphate Phosphatase Activity Regulation Of Peptide Hormone Secretion Positive Regulation Of Tooth Mineralization Chloride Channel Inhibitor Activity Chloride Channel Regulator Activity Regulation Of Enamel Mineralization Membrane Hyperpolarization Negative Regulation Of Peptidyl-serine Phosphorylation Regulation Of Synaptic Vesicle Clustering Postsynaptic Density Assembly Positive Regulation Of Transmission Of Nerve Impulse Regulation Of Glucagon Secretion Developmental Maturation Identical Protein Binding Bicarbonate Transmembrane Transporter Activity Positive Regulation Of Cell Communication Intracellular PH Elevation
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