BNIP1 and TMEM31

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		BNIP1	TMEM31
Description		BCL2 interacting protein 1	transmembrane protein 31
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nuclear Envelope Cytoplasm Mitochondrion Mitochondrial Outer Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane COPI-coated Vesicle SNARE Complex Mitochondrial Membrane Intracellular Membrane-bounded Organelle	Membrane
	Molecular Function	SNAP Receptor Activity Protein Binding Calcium-induced Calcium Release Activity	Protein Binding
	Biological Process	Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Apoptotic Process Endoplasmic Reticulum Organization Response To Activity Vesicle-mediated Transport Endoplasmic Reticulum Membrane Fusion Calcium-mediated Signaling Response To Starvation Negative Regulation Of Apoptotic Process Response To Oxygen-glucose Deprivation Execution Phase Of Apoptosis Apoptotic Process In Response To Mitochondrial Fragmentation
Pathways		COPI-dependent Golgi-to-ER retrograde traffic
Drugs
Diseases
GWAS		Glaucoma (primary open-angle) ( 29891935) Infantile hypertrophic pyloric stenosis ( 22306654) PR interval ( 30046033 30679814 32439900) Pulse pressure ( 30578418)
Interacting Genes		25 interacting genes: APP BCL2 BCL2L1 CYB561 ELOVL4 ERBB2 FAM174A GPR35 HSD17B11 JAGN1 MARCHF5 NAPA NCBP1 PTGER4 RETREG3 SCN3B SLC7A14 STOM STX18 STX1A TM4SF19 TMEM31 TMX2 TSHR VMA21	138 interacting genes: ABHD16A ABHD5 AGPAT4 AGTRAP ANKRD46 APOD ARV1 ATP6V0C BCAP31 BLCAP BMP10 BNIP1 BTN2A2 C14orf180 C2CD2L CAMLG CCL4 CGRRF1 CLDND2 CLN5 CLRN1 CMTM7 CNIH3 COX14 COX20 CTSA CTXN3 CXCL9 CXorf66 CYB561A3 CYB5R3 DEFB103A DEFB103B DEFB105A DEFB105B DERL1 DERL3 DGAT2L6 DHRSX DNAJC30 EBP EHHADH EMP1 ERG28 FAXDC2 FCER1G FKBP8 FXYD6 GIMAP5 GJB2 GJD4 GPR151 GUCA2A GYPA HERPUD2 HIGD1C HSD17B13 HSD3B7 IFITM5 ITGAM LHFPL5 LPAR3 LRAT LY6D MALL MMP14 MS4A1 NAT8 NINJ1 NINJ2 NSDHL ORMDL2 OTOP3 OTULINL PEDS1-UBE2V1 PLN PLP1 PLP2 PMP22 PNLIPRP1 PTPN1 RDH11 REEP2 RETREG3 RNF144A RNF19B RTP2 SELENOK SELENOM SERP2 SGTA SLC30A8 SLC35E4 SLC35H1 SLC39A6 SLC41A1 SLC66A2 SLC71A2 SLC7A14 SMAGP SMIM1 SMIM3 SMPD2 SNORC SPTSSA STX12 STX5 SYNGR1 TEX264 TIMMDC1 TMBIM6 TMEM107 TMEM121 TMEM14A TMEM14C TMEM182 TMEM203 TMEM208 TMEM218 TMEM239 TMEM242 TMEM254 TMEM255B TMEM44 TMEM50A TMEM86A TMX2 TNFRSF10B TRARG1 TSPAN2 TVP23B UBE2J1 VAMP2 VAMP3 VAMP5 YIF1A YIPF6 ZFPL1
Entrez ID		662	203562
HPRD ID		04480	06652
Ensembl ID		ENSG00000113734	ENSG00000179363
Uniprot IDs		Q12981	A0A140VK58 Q5JXX7
PDB IDs
Enriched GO Terms of Interacting Partners?		Membrane Endoplasmic Reticulum Dendritic Cell Apoptotic Process Synaptobrevin 2-SNAP-25-syntaxin-1a Complex BH3 Domain Binding Regulation Of Protein Localization Negative Regulation Of Dendritic Cell Apoptotic Process Bcl-2 Family Protein Complex Regulation Of Cellular Component Organization Regulation Of Cellular Localization Endoplasmic Reticulum Membrane Regulation Of Synaptic Vesicle Priming Regulation Of Biological Quality Cytoplasmic Vesicle Regulation Of Monoatomic Ion Transport Regulation Of Transport Negative Regulation Of Anoikis Regulation Of Membrane Potential Programmed Cell Death Involved In Cell Development Release Of Cytochrome C From Mitochondria Amyloid-beta Complex Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Growth Cone Lamellipodium Regulation Of Calcium Ion Transmembrane Transport Regulation Of Response To Calcium Ion Positive Regulation Of Excitatory Postsynaptic Potential Regulation Of Establishment Of Protein Localization Amylin Binding Neuron Maturation Positive Regulation Of Toll Signaling Pathway Regulation Of Monoatomic Ion Transmembrane Transport Positive Regulation Of Cytosolic Calcium Ion Concentration Negative Regulation Of Retinal Cell Programmed Cell Death Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Negative Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Negative Regulation Of Cellular PH Reduction Leukocyte Proliferation Mononuclear Cell Proliferation Myelin Sheath Regulation Of Anoikis Negative Regulation Of Calcium Ion Transmembrane Transport Apoptotic Process In Bone Marrow Cell Positive Regulation Of Protein Targeting To Membrane Regulation Of Protein Targeting To Membrane Positive Regulation Of RNA Binding Negative Regulation Of Eosinophil Extravasation SNAP Receptor Activity Presynaptic Active Zone Membrane Myosin Head/neck Binding	Membrane Endoplasmic Reticulum Membrane Endoplasmic Reticulum Protein Binding Sterol Biosynthetic Process Lipid Biosynthetic Process Response To Endoplasmic Reticulum Stress Steroid Biosynthetic Process SNAP Receptor Activity Lipid Droplet Lipid Metabolic Process Endoplasmic Reticulum Unfolded Protein Response SNARE Complex Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Bleb Assembly Oxidoreductase Activity, Acting On The CH-OH Group Of Donors, NAD Or NADP As Acceptor Mitochondrial Membrane Regulation Of Retrograde Protein Transport, ER To Cytosol Organelle Membrane Fusion Cholesterol Biosynthetic Process 3-beta-hydroxy-Delta5-steroid Dehydrogenase (NAD+) Activity Establishment Of Protein Localization To Membrane Regulation Of Cellular Localization Regulation Of Intracellular Transport Membrane Destabilizing Activity Cellular Response To Unfolded Protein Endoplasmic Reticulum-Golgi Intermediate Compartment Sterol Metabolic Process Mitochondrial Respiratory Chain Complex Assembly Organelle Fusion Response To Unfolded Protein Regulation Of Protein Exit From Endoplasmic Reticulum Membrane Organization
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