BNIP1 and NCBP1

Number of citations of the paper that reports this interaction (PMID 7478990)
22

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		BNIP1	NCBP1
Gene Name		BCL2/adenovirus E1B 19kDa interacting protein 1	nuclear cap binding protein subunit 1, 80kDa
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nuclear Envelope Cytoplasm Mitochondrion Endoplasmic Reticulum Integral Component Of Endoplasmic Reticulum Membrane SNARE Complex Intracellular Membrane-bounded Organelle	Nucleus Nucleoplasm Cytoplasm Mitochondrion Cytosol MRNA Cap Binding Complex Nuclear Cap Binding Complex Ribonucleoprotein Complex
	Molecular Function	SNAP Receptor Activity Protein Binding	RNA Cap Binding RNA Binding Protein Binding Poly(A) RNA Binding
	Biological Process	Autophagy Apoptotic Process Endoplasmic Reticulum Organization Vesicle-mediated Transport Endoplasmic Reticulum Membrane Fusion Negative Regulation Of Apoptotic Process Execution Phase Of Apoptosis	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Spliceosomal SnRNP Assembly MRNA Splicing, Via Spliceosome Transcription From RNA Polymerase II Promoter Transcription Elongation From RNA Polymerase II Promoter Termination Of RNA Polymerase II Transcription 7-methylguanosine MRNA Capping MRNA Cleavage MRNA Export From Nucleus Regulation Of Translational Initiation Histone MRNA Metabolic Process RNA Splicing Gene Expression Viral Process Gene Silencing By RNA MRNA 3'-end Processing Positive Regulation Of MRNA 3'-end Processing NcRNA Metabolic Process MRNA Cis Splicing, Via Spliceosome Positive Regulation Of Viral Transcription
Pathways			mRNA Splicing Formation of HIV-1 elongation complex containing HIV-1 Tat RNA Polymerase II Transcription Abortive elongation of HIV-1 transcript in the absence of Tat HIV Infection Formation of the Early Elongation Complex Transport of the SLBP independent Mature mRNA Tat-mediated elongation of the HIV-1 transcript Cleavage of Growing Transcript in the Termination Region Processing of Intronless Pre-mRNAs RNA Polymerase II Pre-transcription Events SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs HIV Life Cycle Transport of Mature Transcript to Cytoplasm HIV Transcription Elongation SLBP independent Processing of Histone Pre-mRNAs Nonsense-Mediated Decay (NMD) Transport of Mature mRNA Derived from an Intronless Transcript Processing of Capped Intron-Containing Pre-mRNA Transport of the SLBP Dependant Mature mRNA Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA Capping Transport of Mature mRNAs Derived from Intronless Transcripts mRNA Splicing - Minor Pathway Metabolism of non-coding RNA mRNA Splicing - Major Pathway mRNA 3'-end processing Late Phase of HIV Life Cycle Formation of RNA Pol II elongation complex Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) snRNP Assembly Formation of HIV elongation complex in the absence of HIV Tat Processing of Capped Intronless Pre-mRNA Formation of the HIV-1 Early Elongation Complex RNA Polymerase II Transcription Termination Transcription of the HIV genome Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) RNA Polymerase II Transcription Elongation
Drugs
Diseases
GWAS		Infantile hypertrophic pyloric stenosis ( 22306654)	Thyroid cancer (Papillary, radiation-related) ( 20350937)
Protein-Protein Interactions		6 interactors: APP BCL2 BCL2L1 NAPA NCBP1 STX18	14 interactors: BNIP1 BNIP2 BNIP3 C17orf85 EIF4G1 EIF4G2 HNRNPF HNRNPH1 NCBP2 RNF40 RPS6KB1 SNRPA1 STAU1 ZDHHC17
Entrez ID		662	4686
HPRD ID		04480	02717
Ensembl ID		ENSG00000113734	ENSG00000136937
Uniprot IDs		Q12981	Q09161
PDB IDs			1H2T 1H2U 1H2V 1H6K 1N52 1N54 3FEX 3FEY
Enriched GO Terms of Interacting Partners?		Intracellular Transport Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Neuron Apoptotic Process Neuron Death Establishment Of Localization In Cell Cellular Localization Negative Regulation Of Anoikis Regulation Of Anoikis Intracellular Receptor Signaling Pathway Release Of Cytochrome C From Mitochondria Membrane Organization Negative Regulation Of Autophagy Regulation Of Mitochondrial Membrane Potential Regulation Of Mitochondrial Membrane Permeability Endoplasmic Reticulum Calcium Ion Homeostasis Regulation Of Membrane Permeability Regulation Of Cellular Localization Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Response To Gamma Radiation Transport Positive Regulation Of Intrinsic Apoptotic Signaling Pathway Negative Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Regulation Of Mitotic Cell Cycle Mitochondrial Membrane Organization Ovarian Follicle Development Apoptotic Mitochondrial Changes Response To Radiation Posttranscriptional Regulation Of Gene Expression Growth MRNA 3'-end Processing Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Vesicle-mediated Transport Regulation Of Mitochondrion Organization Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Ovulation Cycle Process Negative Regulation Of Intrinsic Apoptotic Signaling Pathway Negative Regulation Of Cellular PH Reduction CD8-positive, Alpha-beta T Cell Lineage Commitment Apoptotic Process In Bone Marrow Negative Regulation Of Retinal Cell Programmed Cell Death Regulation Of Multicellular Organism Growth Extrinsic Apoptotic Signaling Pathway RNA 3'-end Processing Regulation Of Autophagy Female Gonad Development Ovulation Cycle Development Of Primary Female Sexual Characteristics Membrane Fusion Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Synaptic Growth At Neuromuscular Junction	Regulation Of Translational Initiation MRNA Processing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions MRNA Metabolic Process RNA Processing Regulation Of Translation RNA Splicing Posttranscriptional Regulation Of Gene Expression Cell Death Death Intrinsic Apoptotic Signaling Pathway In Response To Hypoxia Positive Regulation Of Viral Process MRNA 3'-end Processing Cellular Macromolecule Catabolic Process Endoplasmic Reticulum Membrane Fusion SnRNA Export From Nucleus Positive Regulation Of RNA Export From Nucleus Positive Regulation Of Skeletal Muscle Tissue Growth Negative Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Regulation Of RNA Splicing Apoptotic Process Negative Regulation Of Cell Death RNA 3'-end Processing Positive Regulation By Virus Of Viral Protein Levels In Host Cell Response To Electrical Stimulus Involved In Regulation Of Muscle Adaptation Mitochondrial Protein Catabolic Process Programmed Cell Death Catabolic Process Cellular Metabolic Process Skeletal Muscle Atrophy Negative Regulation Of Mitochondrial Fusion Granzyme-mediated Apoptotic Signaling Pathway Nuclear-transcribed MRNA Catabolic Process Viral Process RNA Localization Insulin Receptor Signaling Pathway Autophagic Cell Death Striated Muscle Atrophy Response To Leucine Regulation Of Mitochondrial Fusion Regulation Of Viral Process MRNA Catabolic Process Cellular Response To Cobalt Ion Muscle Atrophy RNA Catabolic Process Skeletal Muscle Adaptation Histone H2B Ubiquitination
Tagcloud ?		adjacent akt1 array bel7402 chemoembolization cytoprotective cytotoxic depletion enhance gadd45a gcb gemcitabine glycoprotein hcc hepatocellular hepatocytes histological parental profiler sclu secretory shrna smmc7721 supported synergistically tnfrsf10a tradd transarterial viability	adaptation cdna delayed elicited equivalent fundamental heat implicates ischaemia ischaemic isoform lethal mediating modulating myocardium pp2 preconditioning rabbit rda rendered reperfusion representational salvage se sham shock tgfbeta trip1 ventricle
Tagcloud (Difference) ?		adjacent akt1 array bel7402 chemoembolization cytoprotective cytotoxic depletion enhance gadd45a gcb gemcitabine glycoprotein hcc hepatocellular hepatocytes histological parental profiler sclu secretory shrna smmc7721 supported synergistically tnfrsf10a tradd transarterial viability	adaptation cdna delayed elicited equivalent fundamental heat implicates ischaemia ischaemic isoform lethal mediating modulating myocardium pp2 preconditioning rabbit rda rendered reperfusion representational salvage se sham shock tgfbeta trip1 ventricle
Tagcloud (Intersection) ?