BNIP1 and NAPA

Number of citations of the paper that reports this interaction (PMID 15272311)
25

Data Source:
HPRD (in vitro)

		BNIP1	NAPA
Gene Name		BCL2/adenovirus E1B 19kDa interacting protein 1	N-ethylmaleimide-sensitive factor attachment protein, alpha
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nuclear Envelope Cytoplasm Mitochondrion Endoplasmic Reticulum Integral Component Of Endoplasmic Reticulum Membrane SNARE Complex Intracellular Membrane-bounded Organelle	Vacuolar Membrane Cytosol Membrane SNARE Complex Synaptobrevin 2-SNAP-25-syntaxin-1a Complex Extracellular Vesicular Exosome
	Molecular Function	SNAP Receptor Activity Protein Binding	Soluble NSF Attachment Protein Activity Protein Binding Syntaxin Binding
	Biological Process	Autophagy Apoptotic Process Endoplasmic Reticulum Organization Vesicle-mediated Transport Endoplasmic Reticulum Membrane Fusion Negative Regulation Of Apoptotic Process Execution Phase Of Apoptosis	Intracellular Protein Transport Intra-Golgi Vesicle-mediated Transport Post-Golgi Vesicle-mediated Transport Brain Development Regulation Of Synaptic Vesicle Priming Neuron Differentiation Synaptic Transmission, Glutamatergic SNARE Complex Disassembly Apical Protein Localization Membrane Organization Membrane Fusion
Pathways			Golgi Associated Vesicle Biogenesis trans-Golgi Network Vesicle Budding Clathrin derived vesicle budding
Drugs
Diseases
GWAS		Infantile hypertrophic pyloric stenosis ( 22306654)
Protein-Protein Interactions		6 interactors: APP BCL2 BCL2L1 NAPA NCBP1 STX18	17 interactors: APP BNIP1 GNA12 GOSR1 GOSR2 NSF RTN4 SNAP23 SNAP25 STX12 STX1A STX4 STX5 STX7 STX8 TRPC3 VAMP8
Entrez ID		662	8775
HPRD ID		04480	04447
Ensembl ID		ENSG00000113734	ENSG00000105402
Uniprot IDs		Q12981	P54920
PDB IDs
Enriched GO Terms of Interacting Partners?		Intracellular Transport Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Neuron Apoptotic Process Neuron Death Establishment Of Localization In Cell Cellular Localization Negative Regulation Of Anoikis Regulation Of Anoikis Intracellular Receptor Signaling Pathway Release Of Cytochrome C From Mitochondria Membrane Organization Negative Regulation Of Autophagy Regulation Of Mitochondrial Membrane Potential Regulation Of Mitochondrial Membrane Permeability Endoplasmic Reticulum Calcium Ion Homeostasis Regulation Of Membrane Permeability Regulation Of Cellular Localization Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Response To Gamma Radiation Transport Positive Regulation Of Intrinsic Apoptotic Signaling Pathway Negative Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Regulation Of Mitotic Cell Cycle Mitochondrial Membrane Organization Ovarian Follicle Development Apoptotic Mitochondrial Changes Response To Radiation Posttranscriptional Regulation Of Gene Expression Growth MRNA 3'-end Processing Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Vesicle-mediated Transport Regulation Of Mitochondrion Organization Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Ovulation Cycle Process Negative Regulation Of Intrinsic Apoptotic Signaling Pathway Negative Regulation Of Cellular PH Reduction CD8-positive, Alpha-beta T Cell Lineage Commitment Apoptotic Process In Bone Marrow Negative Regulation Of Retinal Cell Programmed Cell Death Regulation Of Multicellular Organism Growth Extrinsic Apoptotic Signaling Pathway RNA 3'-end Processing Regulation Of Autophagy Female Gonad Development Ovulation Cycle Development Of Primary Female Sexual Characteristics Membrane Fusion Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Synaptic Growth At Neuromuscular Junction	Membrane Fusion Organelle Fusion Vesicle Fusion Vesicle Organization Membrane Organization Vesicle-mediated Transport Vesicle Docking Membrane Docking Establishment Of Localization In Cell Intracellular Transport Synaptic Vesicle Fusion To Presynaptic Membrane Cellular Localization Protein Transport Golgi Vesicle Transport Establishment Of Protein Localization Exocytosis Post-Golgi Vesicle-mediated Transport Transport Protein Localization Secretion By Cell Regulation Of Protein Localization To Plasma Membrane Synaptic Vesicle Exocytosis Intracellular Protein Transport Organelle Organization Secretion Regulation Of Cellular Localization Neurotransmitter Secretion Synaptic Vesicle Transport Cellular Protein Localization Regulation Of Cellular Component Organization Regulation Of Neurotransmitter Levels Regulation Of Exocytosis Neurotransmitter Transport Intra-Golgi Vesicle-mediated Transport Organelle Localization Platelet Activation Positive Regulation Of Exocytosis Establishment Of Vesicle Localization Regulation Of Protein Localization Endosomal Transport Vesicle Localization Retrograde Transport, Endosome To Golgi Synaptic Vesicle Docking Vesicle Fusion With Golgi Apparatus SNARE Complex Assembly Synaptic Vesicle Priming Regulation Of Hormone Secretion Regulation Of Body Fluid Levels ER To Golgi Vesicle-mediated Transport Synaptic Transmission
Tagcloud ?		adjacent akt1 array bel7402 chemoembolization cytoprotective cytotoxic depletion enhance gadd45a gcb gemcitabine glycoprotein hcc hepatocellular hepatocytes histological parental profiler sclu secretory shrna smmc7721 supported synergistically tnfrsf10a tradd transarterial viability	account activate alter beta cat construct contains cotransfected delta demonstrating element half independence inducing neuroblastoma phenylacetate promoting ra rar rare re reporter retinoic sodium sv synergize synergy upregulating vector
Tagcloud (Difference) ?		adjacent akt1 array bel7402 chemoembolization cytoprotective cytotoxic depletion enhance gadd45a gcb gemcitabine glycoprotein hcc hepatocellular hepatocytes histological parental profiler sclu secretory shrna smmc7721 supported synergistically tnfrsf10a tradd transarterial viability	account activate alter beta cat construct contains cotransfected delta demonstrating element half independence inducing neuroblastoma phenylacetate promoting ra rar rare re reporter retinoic sodium sv synergize synergy upregulating vector
Tagcloud (Intersection) ?