CTNND2 and ATN1

Number of citations of the paper that reports this interaction (PubMedID 10332026)
0

Data Source:
BioGRID (two hybrid)

		CTNND2	ATN1
Description		catenin delta 2	atrophin 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Plasma Membrane Adherens Junction Postsynaptic Density Dendrite Cell Projection Perikaryon Anchoring Junction	Nucleus Nucleoplasm Cytoplasm Nuclear Matrix Perinuclear Region Of Cytoplasm Anchoring Junction
	Molecular Function	Protein Binding Beta-catenin Binding Cadherin Binding	Transcription Coactivator Activity Transcription Corepressor Activity Protein Binding Protein Domain Specific Binding
	Biological Process	Cell Adhesion Signal Transduction Wnt Signaling Pathway Synapse Organization Regulation Of Canonical Wnt Signaling Pathway Dendritic Spine Morphogenesis Cell-cell Adhesion	Negative Regulation Of Transcription By RNA Polymerase II Cell Killing Spermatogenesis Central Nervous System Development Determination Of Adult Lifespan Male Gonad Development Post-embryonic Development Cell Migration Maintenance Of Cell Polarity Response To Food Multicellular Organism Growth Positive Regulation Of DNA-templated Transcription Neuron Apoptotic Process
Pathways			Regulation of PTEN gene transcription
Drugs
Diseases		Cri du chat syndrome; Cat cry syndrome; Chromosme 5p deletion syndrome	Dentatorubropallidoluysian atrophy (DRPLA)
GWAS		Amyotrophic lateral sclerosis (sporadic) ( 24529757) Cannabis dependence symptom count ( 27028160) Clostridioides difficle infection ( 33841421) Cognitive performance (processing speed) ( 31598132) Common carotid intima-media thickness in HIV infection ( 29206233) Corneal astigmatism ( 30306274) Facial emotion recognition ( 28608620) Femur bone mineral density x serum urate levels interaction ( 34046847) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Lewy body disease ( 25188341) Macular thickness ( 30535121) Myopia (pathological) ( 21095009) Pulse pressure ( 27841878) Refractive error ( 32231278) Response to antidepressants (symptom improvement) ( 29160301) Sensorimotor dexterity ( 31596458) Serum docosahexaenoic fatty acid concentration in metabolic syndrome ( 31991592) Systolic blood pressure ( 27841878) Very long-chain saturated fatty acid levels (fatty acid 20:0) ( 25378659)	Refractive error ( 32231278)
Interacting Genes		22 interacting genes: ABL1 ATN1 CDH1 CDH2 CLK1 CTNNB1 CTTN ERBIN FYN LCK LNX1 LRRC7 MAGI2 NCAM2 NUDT21 PDZD2 PSEN1 PSEN2 PTGER4 SPHK1 TBKBP1 TTR	126 interacting genes: AGRN ALG13 ARF3 ATRX BAG3 BAG6 BAIAP2 CACNB1 CASP1 CASP3 CBFA2T2 CHRD CPAP CRACR2A CRIP2 CSNK2A1 CTNND2 DGCR6L DMPK DMRT3 DVL1 DVL2 ECM1 EFEMP1 EFEMP2 ETNK2 EWSR1 FBLN1 FBLN2 FBLN5 FXR1 FXR2 GAPDH GCC1 GIGYF1 GRN HGS HINFP HNRNPF HSPG2 ITCH JAG2 KAT6A KAT6B KAT7 KRT31 KRTAP12-2 KRTAP15-1 KRTAP19-2 KRTAP19-5 KRTAP4-12 KRTAP6-2 KRTAP9-3 LENG8 LRP2 LTBP1 LTBP4 LYST MAGI1 MAGI2 MAP7D1 MBP MDFI MEGF11 MEGF6 MEGF8 NCK2 NELL1 NELL2 NOC2L NR2E1 OLIG3 P4HA3 PCSK5 PDCD6IP PFKL PIN1 PITX1 PITX2 PLSCR1 PRRC2A PRRC2B PSMA3 PSME3 RAD54L2 RBFOX1 RBFOX2 RBM10 RBM14 RBM4B RBPMS RCHY1 RERE RHOXF2 RNF115 RNF31 RUNX1T1 SAXO4 SH3RF1 SHANK3 SIAH1 SIAH2 SLC25A48 SLIT1 SPAG5 SS18L1 SSPOP STXBP4 SYVN1 TEKT3 TEP1 TLE1 TLE5 TNFAIP8 TRIP6 TSC1 USP2 USP54 VIM WDR5 WWP1 WWP2 YAP1 ZMYND8 ZNF503 ZSWIM8
Entrez ID		1501	1822
HPRD ID		09181	06311
Ensembl ID		ENSG00000169862	ENSG00000111676
Uniprot IDs		A0A994J5V2 B4DJU1 B4DRK2 E7EPC8 Q9UQB3	P54259 Q86V38
PDB IDs
Enriched GO Terms of Interacting Partners?		Postsynapse Cell Motility Non-membrane Spanning Protein Tyrosine Kinase Activity Cell Junction Cell Adhesion Synapse Organization T Cell Activation Cell-cell Adhesion Glutamatergic Synapse Catenin Complex Cell-cell Junction T Cell Receptor Signaling Pathway Fc-gamma Receptor Signaling Pathway Cell Migration Anchoring Junction CD8 Receptor Binding Regulation Of Cell Projection Organization Positive Regulation Of Blood Vessel Branching Lymphocyte Activation Regulation Of Neuron Projection Development Protein Tyrosine Kinase Activity Cellular Response To Indole-3-methanol Cell-cell Adhesion Mediated By Cadherin Response To Indole-3-methanol Cell Junction Organization Detection Of Abiotic Stimulus Neuron Projection Organization Growth Factor Receptor Binding Aspartic Endopeptidase Activity, Intramembrane Cleaving Cellular Response To Growth Factor Stimulus Detection Of Mechanical Stimulus Detection Of Muscle Stretch Gamma-secretase Complex Response To Xenobiotic Stimulus Thymus Development Receptor Clustering Positive Regulation Of Neuron Projection Development Intracellular Signal Transduction T Cell Differentiation Regulation Of Synapse Organization Antigen Receptor-mediated Signaling Pathway Regulation Of Blood Vessel Branching Adherens Junction Organization Fascia Adherens Cytoplasm Cadherin Binding Response To Growth Factor Fc Receptor Signaling Pathway Mononuclear Cell Differentiation Activated T Cell Proliferation	Protein Binding Regulation Of Primary Metabolic Process Regulation Of RNA Metabolic Process Positive Regulation Of Macromolecule Metabolic Process Regulation Of Macromolecule Metabolic Process Developmental Process Extracellular Matrix Structural Constituent Positive Regulation Of Metabolic Process Regulation Of Gene Expression Calcium Ion Binding Negative Regulation Of DNA-templated Transcription Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Macromolecule Metabolic Process Negative Regulation Of Metabolic Process Negative Regulation Of RNA Biosynthetic Process Regulation Of Cell Communication Regulation Of Signal Transduction Regulation Of Signaling Regulation Of Macromolecule Biosynthetic Process Regulation Of DNA-templated Transcription Negative Regulation Of RNA Metabolic Process Regulation Of RNA Biosynthetic Process Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Metabolic Process Protein Stabilization Negative Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Macromolecule Biosynthetic Process Intermediate Filament Transcription Corepressor Activity Regulation Of Protein Stability Elastic Fiber Positive Regulation Of Biosynthetic Process Negative Regulation Of Biosynthetic Process Cell Surface Receptor Signaling Pathway Wnt Signaling Pathway System Development Apoptotic Process DNA-binding Transcription Factor Binding Negative Regulation Of Signal Transduction Negative Regulation Of Cell Communication Negative Regulation Of Signaling Programmed Cell Death Cell Death Histone H3 Acetyltransferase Activity Regulation Of Cell Population Proliferation Modulation Of Excitatory Postsynaptic Potential Positive Regulation Of Long-term Neuronal Synaptic Plasticity Regulation Of Cell Projection Organization Signal Transduction Positive Regulation Of RNA Metabolic Process
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