CTNND2 and CDH2

Number of citations of the paper that reports this interaction (PMID 9971746)
41

Data Source:
HPRD (in vivo)

		CTNND2	CDH2
Gene Name		catenin (cadherin-associated protein), delta 2	cadherin 2, type 1, N-cadherin (neuronal)
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Adherens Junction Perikaryon	Plasma Membrane Cell-cell Junction Cell-cell Adherens Junction Fascia Adherens Focal Adhesion Intercalated Disc Integral Component Of Membrane Apical Plasma Membrane Catenin Complex Lamellipodium Synapse Extracellular Vesicular Exosome
	Molecular Function	Protein Binding	Calcium Ion Binding Protein Binding Beta-catenin Binding Protein Phosphatase Binding Alpha-catenin Binding Gamma-catenin Binding
	Biological Process	Morphogenesis Of A Branching Structure Transcription, DNA-templated Regulation Of Transcription, DNA-templated Cell Adhesion Signal Transduction Multicellular Organismal Development Learning Single Organismal Cell-cell Adhesion Regulation Of Synaptic Plasticity	Cell Adhesion Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Glial Cell Differentiation Calcium-dependent Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Cell Migration Cell Junction Assembly Adherens Junction Organization Muscle Cell Differentiation Positive Regulation Of MAPK Cascade Cell-cell Adhesion Mediated By Cadherin Cell-cell Junction Organization Blood Vessel Morphogenesis Striated Muscle Cell Differentiation Positive Regulation Of Muscle Cell Differentiation Negative Regulation Of Canonical Wnt Signaling Pathway Neuronal Stem Cell Maintenance
Pathways			Cell junction organization Cell-cell junction organization CDO in myogenesis Myogenesis Adherens junctions interactions
Drugs
Diseases
GWAS		Myopia (pathological) ( 21095009)	Obesity-related traits ( 23251661) Temperament (bipolar disorder) ( 22365631) vWF and FVIII levels ( 21810271)
Protein-Protein Interactions		18 interactors: ABL1 ATN1 CDH1 CDH2 CTNNB1 CTTN ERBB2IP FYN LCK LNX1 LRRC7 MAGI2 NUDT21 PDZD2 PSEN1 PSEN2 SPHK1 TTR	22 interactors: ARHGAP32 ARVCF BOC CDH11 CDH4 CDON CREBBP CTNNA1 CTNNB1 CTNND2 EXOC5 FGFR4 GNA12 GNA13 GRIK2 GRIN1 GRIN2D JUP LRRC7 PIK3R1 PKP4 PTPN1
Entrez ID		1501	1000
HPRD ID		09181	00226
Ensembl ID		ENSG00000169862	ENSG00000170558
Uniprot IDs		B4DRK2 E7EPC8 Q9UQB3	A8MWK3 P19022
PDB IDs
Enriched GO Terms of Interacting Partners?		Cell Adhesion Single Organismal Cell-cell Adhesion Negative Regulation Of Signal Transduction Regulation Of Cell Differentiation T Cell Aggregation T Cell Activation Lymphocyte Aggregation Leukocyte Aggregation Negative Regulation Of Signaling Antigen Receptor-mediated Signaling Pathway Neurogenesis Cell Migration Thymus Development Leukocyte Cell-cell Adhesion Nervous System Development Locomotion Homotypic Cell-cell Adhesion Cell Motility Central Nervous System Development Regulation Of Apoptotic Process Movement Of Cell Or Subcellular Component Lymphocyte Activation Regulation Of Neurogenesis Regulation Of Cell Death Generation Of Neurons Regulation Of Signal Transduction Adherens Junction Organization Brain Development Negative Regulation Of Apoptotic Signaling Pathway Leukocyte Activation Head Development Positive Regulation Of Intracellular Signal Transduction T Cell Receptor Signaling Pathway Positive Regulation Of Signal Transduction Regulation Of Cell Development Regulation Of Signaling Positive Regulation Of Cell Differentiation Cell Development Immune Response-activating Cell Surface Receptor Signaling Pathway Negative Regulation Of Apoptotic Process Enzyme Linked Receptor Protein Signaling Pathway Negative Regulation Of Programmed Cell Death Cellular Component Assembly Cellular Response To Growth Factor Stimulus Regulation Of Cellular Component Organization System Development Response To Growth Factor Negative Regulation Of Cell Death Leukocyte Differentiation Apoptotic Process	Cellular Response To Indole-3-methanol Adherens Junction Organization Cell Junction Assembly Cell-cell Junction Organization Cell Adhesion Regulation Of Signaling Cell Surface Receptor Signaling Pathway Signaling Cell Communication Signal Transduction Multicellular Organismal Development Regulation Of Signal Transduction Positive Regulation Of Muscle Cell Differentiation Anatomical Structure Morphogenesis Cellular Response To Organonitrogen Compound Regulation Of Cell Differentiation Single Organismal Cell-cell Adhesion Developmental Process Response To Organonitrogen Compound Cellular Response To Stimulus Cell Differentiation Anatomical Structure Development Ionotropic Glutamate Receptor Signaling Pathway Synaptic Transmission, Glutamatergic Regulation Of Muscle Cell Differentiation Response To Stimulus Regulation Of Cellular Component Organization Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Glutamate Receptor Signaling Pathway Movement Of Cell Or Subcellular Component Platelet Activation Neuron-neuron Synaptic Transmission Embryonic Digit Morphogenesis Regulation Of Cell Morphogenesis Regulation Of Neural Precursor Cell Proliferation Locomotion Regulation Of Intracellular Signal Transduction Epithelial Cell-cell Adhesion Cell-cell Junction Assembly Enzyme Linked Receptor Protein Signaling Pathway Axon Development Cell-cell Signaling Vascular Endothelial Growth Factor Receptor Signaling Pathway Homeostatic Process Cellular Component Assembly Protein Heterooligomerization Regulation Of Cell Fate Specification Cellular Response To Peptide Hormone Stimulus Muscle Cell Differentiation Regulation Of MAPK Cascade
Tagcloud ?		16p11 17q21 2p21 acot7 autism auts2 cask categorised cnvs crebbp delineating exonic grm8 homozygous incidental instrumental iq kb med13l microdeletion morbid ndds neurodevelopmental nrxn3 omim pafah1b1 satb2 sizing undiagnosed	bioinformatics blotting cadherin downregulating embedded expressions fixed formalin igf1r immunohistochemistry lentiviruses luciferase metastasis mir os osteosarcoma paraffin paraformalin partially predicted probably promising prove quantitative real reporter sosp transfected u2
Tagcloud (Difference) ?		16p11 17q21 2p21 acot7 autism auts2 cask categorised cnvs crebbp delineating exonic grm8 homozygous incidental instrumental iq kb med13l microdeletion morbid ndds neurodevelopmental nrxn3 omim pafah1b1 satb2 sizing undiagnosed	bioinformatics blotting cadherin downregulating embedded expressions fixed formalin igf1r immunohistochemistry lentiviruses luciferase metastasis mir os osteosarcoma paraffin paraformalin partially predicted probably promising prove quantitative real reporter sosp transfected u2
Tagcloud (Intersection) ?