CTNND2 and TBKBP1

Number of citations of the paper that reports this interaction (PubMedID 19481056)
0

Data Source:
BioGRID (two hybrid)

		CTNND2	TBKBP1
Description		catenin delta 2	TBK1 binding protein 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Plasma Membrane Adherens Junction Postsynaptic Density Dendrite Cell Projection Perikaryon Anchoring Junction	Cytoplasm Serine/threonine Protein Kinase Complex
	Molecular Function	Protein Binding Beta-catenin Binding Cadherin Binding	Protein Binding Zinc Ion Binding Metal Ion Binding
	Biological Process	Cell Adhesion Signal Transduction Wnt Signaling Pathway Synapse Organization Regulation Of Canonical Wnt Signaling Pathway Dendritic Spine Morphogenesis Cell-cell Adhesion	Immune System Process Innate Immune Response Defense Response To Virus Type I Interferon-mediated Signaling Pathway
Pathways
Drugs
Diseases		Cri du chat syndrome; Cat cry syndrome; Chromosme 5p deletion syndrome
GWAS		Amyotrophic lateral sclerosis (sporadic) ( 24529757) Cannabis dependence symptom count ( 27028160) Clostridioides difficle infection ( 33841421) Cognitive performance (processing speed) ( 31598132) Common carotid intima-media thickness in HIV infection ( 29206233) Corneal astigmatism ( 30306274) Facial emotion recognition ( 28608620) Femur bone mineral density x serum urate levels interaction ( 34046847) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Lewy body disease ( 25188341) Macular thickness ( 30535121) Myopia (pathological) ( 21095009) Pulse pressure ( 27841878) Refractive error ( 32231278) Response to antidepressants (symptom improvement) ( 29160301) Sensorimotor dexterity ( 31596458) Serum docosahexaenoic fatty acid concentration in metabolic syndrome ( 31991592) Systolic blood pressure ( 27841878) Very long-chain saturated fatty acid levels (fatty acid 20:0) ( 25378659)	Ankylosing spondylitis ( 21743469 23749187) Asthma ( 31619474) Asthma (childhood onset) ( 31036433) Body mass index ( 26426971 28448500) Body mass index (joint analysis main effects and physical activity interaction) ( 28448500) Body mass index in physically inactive individuals ( 28448500) Human herpes virus 7 U14 antibody levels ( 33204752) Mean corpuscular hemoglobin ( 32888494) Multiple sclerosis ( 22190364) Very long-chain saturated fatty acid levels (fatty acid 20:0) ( 25378659)
Interacting Genes		22 interacting genes: ABL1 ATN1 CDH1 CDH2 CLK1 CTNNB1 CTTN ERBIN FYN LCK LNX1 LRRC7 MAGI2 NCAM2 NUDT21 PDZD2 PSEN1 PSEN2 PTGER4 SPHK1 TBKBP1 TTR	6 interacting genes: AGO2 APBA3 CTNND2 IRAK1 KLHL2 TUBB
Entrez ID		1501	9755
HPRD ID		09181	12239
Ensembl ID		ENSG00000169862	ENSG00000198933
Uniprot IDs		A0A994J5V2 B4DJU1 B4DRK2 E7EPC8 Q9UQB3	A7MCY6
PDB IDs
Enriched GO Terms of Interacting Partners?		Postsynapse Cell Motility Non-membrane Spanning Protein Tyrosine Kinase Activity Cell Junction Cell Adhesion Synapse Organization T Cell Activation Cell-cell Adhesion Glutamatergic Synapse Catenin Complex Cell-cell Junction T Cell Receptor Signaling Pathway Fc-gamma Receptor Signaling Pathway Cell Migration Anchoring Junction CD8 Receptor Binding Regulation Of Cell Projection Organization Positive Regulation Of Blood Vessel Branching Lymphocyte Activation Regulation Of Neuron Projection Development Protein Tyrosine Kinase Activity Cellular Response To Indole-3-methanol Cell-cell Adhesion Mediated By Cadherin Response To Indole-3-methanol Cell Junction Organization Detection Of Abiotic Stimulus Neuron Projection Organization Growth Factor Receptor Binding Aspartic Endopeptidase Activity, Intramembrane Cleaving Cellular Response To Growth Factor Stimulus Detection Of Mechanical Stimulus Detection Of Muscle Stretch Gamma-secretase Complex Response To Xenobiotic Stimulus Thymus Development Receptor Clustering Positive Regulation Of Neuron Projection Development Intracellular Signal Transduction T Cell Differentiation Regulation Of Synapse Organization Antigen Receptor-mediated Signaling Pathway Regulation Of Blood Vessel Branching Adherens Junction Organization Fascia Adherens Cytoplasm Cadherin Binding Response To Growth Factor Fc Receptor Signaling Pathway Mononuclear Cell Differentiation Activated T Cell Proliferation
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