CTNND2 and PDZD2

Number of citations of the paper that reports this interaction (PMID 10896674)
15

Data Source:
HPRD (two hybrid, in vivo, in vitro)

		CTNND2	PDZD2
Gene Name		catenin (cadherin-associated protein), delta 2	PDZ domain containing 2
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Adherens Junction Perikaryon	Extracellular Region Nucleus Cytoplasm Endoplasmic Reticulum Cell-cell Junction
	Molecular Function	Protein Binding
	Biological Process	Morphogenesis Of A Branching Structure Transcription, DNA-templated Regulation Of Transcription, DNA-templated Cell Adhesion Signal Transduction Multicellular Organismal Development Learning Single Organismal Cell-cell Adhesion Regulation Of Synaptic Plasticity	Cell Adhesion
Pathways
Drugs
Diseases
GWAS		Myopia (pathological) ( 21095009)	Obesity-related traits ( 23251661) Renal cell carcinoma ( 23184150)
Protein-Protein Interactions		18 interactors: ABL1 ATN1 CDH1 CDH2 CTNNB1 CTTN ERBB2IP FYN LCK LNX1 LRRC7 MAGI2 NUDT21 PDZD2 PSEN1 PSEN2 SPHK1 TTR	5 interactors: BAI1 CST3 CTNND2 NRXN1 PKP4
Entrez ID		1501	23037
HPRD ID		09181	10142
Ensembl ID		ENSG00000169862	ENSG00000133401
Uniprot IDs		B4DRK2 E7EPC8 Q9UQB3	O15018
PDB IDs
Enriched GO Terms of Interacting Partners?		Cell Adhesion Single Organismal Cell-cell Adhesion Negative Regulation Of Signal Transduction Regulation Of Cell Differentiation T Cell Aggregation T Cell Activation Lymphocyte Aggregation Leukocyte Aggregation Negative Regulation Of Signaling Antigen Receptor-mediated Signaling Pathway Neurogenesis Cell Migration Thymus Development Leukocyte Cell-cell Adhesion Nervous System Development Locomotion Homotypic Cell-cell Adhesion Cell Motility Central Nervous System Development Regulation Of Apoptotic Process Movement Of Cell Or Subcellular Component Lymphocyte Activation Regulation Of Neurogenesis Regulation Of Cell Death Generation Of Neurons Regulation Of Signal Transduction Adherens Junction Organization Brain Development Negative Regulation Of Apoptotic Signaling Pathway Leukocyte Activation Head Development Positive Regulation Of Intracellular Signal Transduction T Cell Receptor Signaling Pathway Positive Regulation Of Signal Transduction Regulation Of Cell Development Regulation Of Signaling Positive Regulation Of Cell Differentiation Cell Development Immune Response-activating Cell Surface Receptor Signaling Pathway Negative Regulation Of Apoptotic Process Enzyme Linked Receptor Protein Signaling Pathway Negative Regulation Of Programmed Cell Death Cellular Component Assembly Cellular Response To Growth Factor Stimulus Regulation Of Cellular Component Organization System Development Response To Growth Factor Negative Regulation Of Cell Death Leukocyte Differentiation Apoptotic Process	Cell Adhesion Single Organismal Cell-cell Adhesion Protein Complex Assembly Involved In Synapse Maturation Negative Regulation Of Elastin Catabolic Process Negative Regulation Of Blood Vessel Remodeling Gamma-aminobutyric Acid Receptor Clustering Negative Regulation Of Collagen Catabolic Process Learning Guanylate Kinase-associated Protein Clustering Neuroligin Clustering Gephyrin Clustering Synaptic Vesicle Clustering Regulation Of Collagen Catabolic Process Negative Regulation Of Extracellular Matrix Organization Negative Regulation Of Extracellular Matrix Disassembly Neuronal Signal Transduction N-methyl-D-aspartate Receptor Clustering Vocal Learning Negative Regulation Of Filopodium Assembly Regulation Of Blood Vessel Remodeling Postsynaptic Membrane Assembly Learning Or Memory Synapse Maturation Regulation Of Grooming Behavior Cognition Regulation Of Synaptic Transmission Presynaptic Membrane Assembly Postsynaptic Density Protein 95 Clustering Receptor Localization To Synapse Negative Regulation Of Multicellular Organismal Metabolic Process Presynaptic Membrane Organization Auditory Behavior Extracellular Matrix Organization Extracellular Structure Organization Negative Regulation Of Glycoprotein Metabolic Process Extracellular Fibril Organization Cerebellar Granule Cell Differentiation Vocalization Behavior Prepulse Inhibition Neuron Cell-cell Adhesion Positive Regulation Of Synapse Maturation Single-organism Behavior Negative Regulation Of Tissue Remodeling Mechanosensory Behavior Cerebellar Granular Layer Morphogenesis Response To Auditory Stimulus Regulation Of Synapse Maturation Protein Localization To Synapse Regulation Of Alpha-amino-3-hydroxy-5-methyl-4-isoxazole Propionate Selective Glutamate Receptor Activity Membrane Assembly
Tagcloud ?		16p11 17q21 2p21 acot7 autism auts2 cask categorised cnvs crebbp delineating exonic grm8 homozygous incidental instrumental iq kb med13l microdeletion morbid ndds neurodevelopmental nrxn3 omim pafah1b1 satb2 sizing undiagnosed	1e appeared basal defect deficient depleted displayed duplexes enriched exocrine explore fasting glucose gross homozygous ins intraperitoneal islet islets morphology multi pancreatic secretion sirna tolerance twofold verify viable
Tagcloud (Difference) ?		16p11 17q21 2p21 acot7 autism auts2 cask categorised cnvs crebbp delineating exonic grm8 incidental instrumental iq kb med13l microdeletion morbid ndds neurodevelopmental nrxn3 omim pafah1b1 satb2 sizing undiagnosed	1e appeared basal defect deficient depleted displayed duplexes enriched exocrine explore fasting glucose gross ins intraperitoneal islet islets morphology multi pancreatic secretion sirna tolerance twofold verify viable
Tagcloud (Intersection) ?		homozygous