FAM241B and SUSD6

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		FAM241B	SUSD6
Description		family with sequence similarity 241 member B	sushi domain containing 6
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Membrane Intracellular Membrane-bounded Organelle	Membrane
	Molecular Function	Protein Binding	Protein Binding
	Biological Process		DNA Damage Response
Pathways
Drugs
Diseases
GWAS		Type 2 diabetes ( 30054458)
Interacting Genes		27 interacting genes: ADRA1A BIK BLCAP BNIP3 CD79A CGRRF1 CISD2 ERBB2 ERBB3 ERBB4 HSD17B11 KASH5 MOSPD1 MTNR1A REEP4 RNF185 RNF5 SCN3B SLC10A1 SLC39A11 SLC7A1 SUSD6 SYNE4 TMEM234 TMX2 TRHR ZDHHC15	9 interacting genes: ADAMTSL4 DCUN1D1 FAM241B KRTAP1-3 KRTAP10-8 MTURN OTULIN TMEM19 UBXN6
Entrez ID		219738	9766
HPRD ID		12573	10010
Ensembl ID		ENSG00000171224	ENSG00000100647
Uniprot IDs		Q96D05	Q92537
PDB IDs
Enriched GO Terms of Interacting Partners?		Membrane ERBB3:ERBB2 Complex Basal Plasma Membrane ERBB2 Signaling Pathway Neuregulin Receptor Activity Protein Localization To Postsynapse ErbB-3 Class Receptor Binding ERBB2-ERBB4 Signaling Pathway Basolateral Plasma Membrane Ubiquitin-like Protein Conjugating Enzyme Binding Endoplasmic Reticulum ERBB2-ERBB3 Signaling Pathway ERBB3 Signaling Pathway ERBB4 Signaling Pathway Mitochondrial Fragmentation Involved In Apoptotic Process Protein Localization To Synapse Meiotic Nuclear Membrane Microtubule Tethering Complex Epidermal Growth Factor Receptor Signaling Pathway Apoptotic Mitochondrial Changes Mitochondrial Membrane Endoplasmic Reticulum Mannose Trimming Receptor Complex ERBB Signaling Pathway Protein Localization To Cell Junction Protein Alpha-1,2-demannosylation Schwann Cell Development Neurotransmitter Receptor Localization To Postsynaptic Specialization Membrane Protein Deglycosylation Glial Cell Differentiation Endoplasmic Reticulum Quality Control Compartment Positive Regulation Of Release Of Cytochrome C From Mitochondria Peripheral Nervous System Development Heart Development Positive Regulation Of Heart Rate Endoplasmic Reticulum Membrane Protein Tyrosine Kinase Activity Nuclear Outer Membrane Protein Localization To Postsynaptic Membrane Protein Localization To Membrane Negative Regulation Of Heart Rate Involved In Baroreceptor Response To Increased Systemic Arterial Blood Pressure Positive Regulation Of Heart Contraction Mitochondrion Autophagosome Adaptor Activity Establishment Of Planar Polarity Involved In Nephron Morphogenesis Thyrotropin-releasing Hormone Receptor Activity Regulation Of Release Of Cytochrome C From Mitochondria Oligodendrocyte Differentiation Apoptotic Process Growth Factor Binding Cell Death Positive Regulation Of The Force Of Heart Contraction By Epinephrine-norepinephrine	Pigment Cell Development Negative Regulation Of DNA-binding Transcription Factor Activity Negative Regulation Of NF-kappaB Transcription Factor Activity
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