FAM241B and CD79A

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		FAM241B	CD79A
Description		family with sequence similarity 241 member B	CD79a molecule
Image		No pdb structure
GO Annotations	Cellular Component	Membrane Intracellular Membrane-bounded Organelle	Multivesicular Body Plasma Membrane External Side Of Plasma Membrane Membrane B Cell Receptor Complex Membrane Raft IgM B Cell Receptor Complex
	Molecular Function	Protein Binding	Transmembrane Signaling Receptor Activity Protein Binding Identical Protein Binding
	Biological Process		Adaptive Immune Response Immune System Process Cell Surface Receptor Signaling Pathway B Cell Differentiation B Cell Proliferation B Cell Activation B Cell Receptor Signaling Pathway
Pathways			CD22 mediated BCR regulation Potential therapeutics for SARS Antigen activates B Cell Receptor (BCR) leading to generation of second messengers Antigen activates B Cell Receptor (BCR) leading to generation of second messengers
Drugs
Diseases			Agammaglobulinemias, including the following six diseases: X-linked agammaglobulinemia (Bruton's agammaglobulinemia, XLA); IgM heavy chain gene deletions; Ig-alpha defect; Autosomal recessive agammaglobulinaemia; B cell-linker protein (BLNK) deficiency; Leucine-rich repeat-containing 8
GWAS		Type 2 diabetes ( 30054458)	Brain morphology (MOSTest) ( 32665545)
Interacting Genes		27 interacting genes: ADRA1A BIK BLCAP BNIP3 CD79A CGRRF1 CISD2 ERBB2 ERBB3 ERBB4 HSD17B11 KASH5 MOSPD1 MTNR1A REEP4 RNF185 RNF5 SCN3B SLC10A1 SLC39A11 SLC7A1 SUSD6 SYNE4 TMEM234 TMX2 TRHR ZDHHC15	192 interacting genes: ADGRE2 ADIPOQ AGTRAP ALG10 ALG10B ALG3 APOD AQP1 AQP3 ARLN ATP6V0C BCL2L2 BET1 BLK BLNK BRICD5 BTN2A2 C14orf180 C1GALT1 C2CD2L CATSPERH CCDC167 CD19 CD5 CD79B CD81 CDIPT CLDN1 CLN6 CMTM5 CMTM7 CNIH1 CNIH3 COL4A5 CTSA CTXN3 CYB561 CYB561A3 CYB561D2 CYB5B DEFB127 DOLK EDDM3B EMC6 EMP1 EMP3 FA2H FAM241B FANCA FATE1 FAXDC2 FCAR FDFT1 FFAR3 FKBP8 FUNDC2 FXYD3 FYN GALNT15 GIMAP1 GJB1 GPR42 HACD4 HCLS1 HMOX1 HMOX2 HTATIP2 IER3 IGHM INSIG2 ITGAM JAGN1 JCHAIN KCNS2 LAMB1 LCK LEPROTL1 LHFPL5 LNPEP LPAR3 LTC4S LYN MALL MARCHF2 MFF MFSD12 MFSD6 MGLL MMD2 MOSPD3 MS4A13 MYADM MYADML2 NAT8 NEU1 NINJ2 NIPAL3 NKG7 ORMDL1 ORMDL2 OTOP2 PEX16 PGAP2 PIGR PKMYT1 PLP2 PLPP6 PLPPR2 PNLIPRP1 PRAF2 PTCH1 PTPN6 REEP6 RHO RTP2 SACM1L SEC22B SERP1 SFTPC SLC13A4 SLC13A5 SLC16A12 SLC16A13 SLC30A2 SLC30A3 SLC35B1 SLC35B4 SLC38A1 SLC39A2 SLC39A9 SLC41A1 SLC41A2 SLC46A3 SLC61A1 SLC66A2 SLC6A12 SLC7A1 SMCO4 SMIM3 STRIT1 STX12 STX3 STX8 SYK SYNJ2BP TECR THBD TM4SF19 TM4SF4 TMBIM6 TMEM107 TMEM11 TMEM128 TMEM140 TMEM147 TMEM14B TMEM176A TMEM187 TMEM19 TMEM218 TMEM222 TMEM229B TMEM239 TMEM243 TMEM254 TMEM42 TMEM86A TMEM86B TMEM97 TMPPE TNFRSF10C TRAM1L1 TRARG1 TSNARE1 TSPAN2 TSPO2 UBE2J1 UBIAD1 UNC93B1 UPK1B VAMP3 VAMP4 VAPA VAPB VTI1B WFDC2 WFS1 YIF1A YIPF4 YIPF6 ZDHHC15 ZDHHC22
Entrez ID		219738	973
HPRD ID		12573	00203
Ensembl ID		ENSG00000171224	ENSG00000105369
Uniprot IDs		Q96D05	P11912
PDB IDs			1CV9 7WSO 7WSP 7XQ8 7XT6
Enriched GO Terms of Interacting Partners?		Membrane ERBB3:ERBB2 Complex Basal Plasma Membrane ERBB2 Signaling Pathway Neuregulin Receptor Activity Protein Localization To Postsynapse ErbB-3 Class Receptor Binding ERBB2-ERBB4 Signaling Pathway Basolateral Plasma Membrane Ubiquitin-like Protein Conjugating Enzyme Binding Endoplasmic Reticulum ERBB2-ERBB3 Signaling Pathway ERBB3 Signaling Pathway ERBB4 Signaling Pathway Mitochondrial Fragmentation Involved In Apoptotic Process Protein Localization To Synapse Meiotic Nuclear Membrane Microtubule Tethering Complex Epidermal Growth Factor Receptor Signaling Pathway Apoptotic Mitochondrial Changes Mitochondrial Membrane Endoplasmic Reticulum Mannose Trimming Receptor Complex ERBB Signaling Pathway Protein Localization To Cell Junction Protein Alpha-1,2-demannosylation Schwann Cell Development Neurotransmitter Receptor Localization To Postsynaptic Specialization Membrane Protein Deglycosylation Glial Cell Differentiation Endoplasmic Reticulum Quality Control Compartment Positive Regulation Of Release Of Cytochrome C From Mitochondria Peripheral Nervous System Development Heart Development Positive Regulation Of Heart Rate Endoplasmic Reticulum Membrane Protein Tyrosine Kinase Activity Nuclear Outer Membrane Protein Localization To Postsynaptic Membrane Protein Localization To Membrane Negative Regulation Of Heart Rate Involved In Baroreceptor Response To Increased Systemic Arterial Blood Pressure Positive Regulation Of Heart Contraction Mitochondrion Autophagosome Adaptor Activity Establishment Of Planar Polarity Involved In Nephron Morphogenesis Thyrotropin-releasing Hormone Receptor Activity Regulation Of Release Of Cytochrome C From Mitochondria Oligodendrocyte Differentiation Apoptotic Process Growth Factor Binding Cell Death Positive Regulation Of The Force Of Heart Contraction By Epinephrine-norepinephrine	Membrane Endoplasmic Reticulum Membrane Endoplasmic Reticulum Protein Binding B Cell Receptor Signaling Pathway Plasma Membrane Transmembrane Transport Golgi Membrane SNAP Receptor Activity SNARE Complex Antigen Receptor-mediated Signaling Pathway Cellular Localization Membrane Docking Immune Response-regulating Cell Surface Receptor Signaling Pathway Membrane Fusion Vesicle Fusion Organelle Fusion Organelle Membrane Fusion Organelle Localization By Membrane Tethering Vesicle Organization Immune Response-activating Cell Surface Receptor Signaling Pathway Regulation Of Cellular Localization Localization Within Membrane Protein Localization To Membrane T Cell Costimulation Chemical Homeostasis Membrane Organization Cholesterol Binding Immune Response-regulating Signaling Pathway Peptidyl-tyrosine Phosphorylation Monoatomic Cation Transmembrane Transporter Activity Intracellular Chemical Homeostasis Fc Receptor Signaling Pathway Metal Ion Transport Vesicle Fusion With Golgi Apparatus Vesicle-mediated Transport Endomembrane System Immune Response-activating Signaling Pathway Vesicle Docking Inorganic Cation Transmembrane Transport Membrane Lipid Metabolic Process Vacuolar Transmembrane Transport Phospholipase Binding Monoatomic Cation Transmembrane Transport Regulation Of Transport Regulation Of Immune System Process Establishment Of Localization In Cell Monoatomic Cation Transport Inorganic Ion Transmembrane Transport Monoatomic Ion Transport
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