KRTAP8-1 and FOXD2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		KRTAP8-1	FOXD2
Description		keratin associated protein 8-1	forkhead box D2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol Intermediate Filament	Chromatin Nucleus
	Molecular Function	Protein Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Sequence-specific DNA Binding Sequence-specific Double-stranded DNA Binding
	Biological Process		Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Anatomical Structure Morphogenesis Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II
Pathways		Keratinization
Drugs
Diseases
GWAS		Gut microbiota (bacterial taxa) ( 27723756) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223)	Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (min-P) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Cortical volume ( 32963231) Estimated glomerular filtration rate ( 31152163) LDL cholesterol levels x long total sleep time interaction (2df test) ( 31719535) Male-pattern baldness ( 29146897) Microalbuminuria ( 31511532) Obesity-related traits ( 23251661) Response to anti-depressant treatment in major depressive disorder ( 22041458) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Urinary albumin excretion ( 30220432) Urinary albumin excretion (no hypertensive medication) ( 30220432) Urinary albumin-to-creatinine ratio ( 31630189 31511532 30910378) Urinary albumin-to-creatinine ratio in diabetes ( 31511532) Vaginal microbiome composition (L. iners) ( 32723796)
Interacting Genes		78 interacting genes: AANAT AGXT AOC1 ARID5A ATG9A ATXN1L BANP BCAS2 BHLHE40 C11orf16 C1orf94 CAMK2A CCDC17 CCNK CDA CERCAM CIMIP1 CREB5 CRYAB CYSRT1 DAB1 DAZAP2 DMRTB1 DTX2 FAAP20 FAM168A FAM83A FOXD2 FOXP3 GATA2 GCM2 GLIS2 HEY2 HOXC8 HYPK KRTAP12-4 KRTAP19-5 KRTAP26-1 MKRN3 MYOZ3 NKX2-5 NOXA1 P4HA3 PAX3 PITX1 PLSCR4 POGZ POU6F2 PROP1 PRR13 PRR35 PSMA3 RAMAC RBPMS RBPMS2 RNF38 RUSC1 SAXO4 SLC68A1 SMR3A SMUG1 SNRPC TBX18 TEKT3 TIAL1 TLE5 TLX3 TMSB4X TNIP1 TNPO2 TSPYL6 VENTX VEZF1 YTHDF1 ZBTB32 ZC3H10 ZIC1 ZNF34	18 interacting genes: ARID5A CADPS CYSRT1 FOXH1 KRTAP15-1 KRTAP19-2 KRTAP19-7 KRTAP21-2 KRTAP22-1 KRTAP3-2 KRTAP6-2 KRTAP6-3 KRTAP8-1 MAGED1 NOTO POU2AF1 SPMIP9 TLE5
Entrez ID		337879	2306
HPRD ID		11221	03735
Ensembl ID		ENSG00000183640	ENSG00000186564
Uniprot IDs		Q8IUC2	O60548
PDB IDs
Enriched GO Terms of Interacting Partners?		Sequence-specific Double-stranded DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Nucleus Chromatin DNA Binding Protein Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Transcription By RNA Polymerase II Regulation Of RNA Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process DNA-binding Transcription Factor Activity DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Positive Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Positive Regulation Of RNA Metabolic Process Positive Regulation Of Transcription By RNA Polymerase II Sequence-specific DNA Binding Cytoplasmic Stress Granule Protein Homodimerization Activity Identical Protein Binding Regulation Of Gene Expression Nucleoplasm Regulation Of Primary Metabolic Process Cell Fate Commitment Regulation Of Macromolecule Biosynthetic Process DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Negative Regulation Of Muscle Cell Differentiation Pituitary Gland Development Negative Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Biosynthetic Process Cardiac Muscle Cell Fate Commitment Central Nervous System Development Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Positive Regulation Of Macromolecule Biosynthetic Process Cardiac Muscle Cell Development Ventricular Cardiac Muscle Cell Development Cardiac Cell Development	Intermediate Filament
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