KRTAP8-1 and RAMAC

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		KRTAP8-1	RAMAC
Description		keratin associated protein 8-1	RNA guanine-7 methyltransferase activating subunit
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol Intermediate Filament	Nucleus MRNA Capping Enzyme Complex MRNA Cap Methyltransferase RNMT:RAMAC Complex
	Molecular Function	Protein Binding	RNA Binding Protein Binding Enzyme Activator Activity Molecular Function Activator Activity
	Biological Process		7-methylguanosine MRNA Capping MRNA Processing RNA 5'-cap (guanine-N7)-methylation
Pathways		Keratinization
Drugs
Diseases
GWAS		Gut microbiota (bacterial taxa) ( 27723756) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223)
Interacting Genes		78 interacting genes: AANAT AGXT AOC1 ARID5A ATG9A ATXN1L BANP BCAS2 BHLHE40 C11orf16 C1orf94 CAMK2A CCDC17 CCNK CDA CERCAM CIMIP1 CREB5 CRYAB CYSRT1 DAB1 DAZAP2 DMRTB1 DTX2 FAAP20 FAM168A FAM83A FOXD2 FOXP3 GATA2 GCM2 GLIS2 HEY2 HOXC8 HYPK KRTAP12-4 KRTAP19-5 KRTAP26-1 MKRN3 MYOZ3 NKX2-5 NOXA1 P4HA3 PAX3 PITX1 PLSCR4 POGZ POU6F2 PROP1 PRR13 PRR35 PSMA3 RAMAC RBPMS RBPMS2 RNF38 RUSC1 SAXO4 SLC68A1 SMR3A SMUG1 SNRPC TBX18 TEKT3 TIAL1 TLE5 TLX3 TMSB4X TNIP1 TNPO2 TSPYL6 VENTX VEZF1 YTHDF1 ZBTB32 ZC3H10 ZIC1 ZNF34	47 interacting genes: AKAP8L BAG4 BPIFA1 C10orf55 CYSRT1 DAB1 DAZAP2 DMRTB1 FAM168B FOXI1 GOLGA2 HNRNPH1 HNRNPK INCA1 KRT15 KRT31 KRT33B KRTAP1-3 KRTAP8-1 LZTS2 MAGED1 MAPK1IP1L NAF1 OXER1 PEA15 PLSCR1 PLSCR4 POU2AF1 PRR3 PSMA3 RBMX RBMY1F RBPMS RHOXF2 RINT1 SF3B4 SNRPC TEKT3 TEKT4 TNS2 TRIM23 TRIM27 TRIM42 UBC USP54 VPS37C WWOX
Entrez ID		337879	83640
HPRD ID		11221	12845
Ensembl ID		ENSG00000183640	ENSG00000169612
Uniprot IDs		Q8IUC2	Q9BTL3
PDB IDs			5E8J
Enriched GO Terms of Interacting Partners?		Sequence-specific Double-stranded DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Nucleus Chromatin DNA Binding Protein Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Transcription By RNA Polymerase II Regulation Of RNA Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process DNA-binding Transcription Factor Activity DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Positive Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Positive Regulation Of RNA Metabolic Process Positive Regulation Of Transcription By RNA Polymerase II Sequence-specific DNA Binding Cytoplasmic Stress Granule Protein Homodimerization Activity Identical Protein Binding Regulation Of Gene Expression Nucleoplasm Regulation Of Primary Metabolic Process Cell Fate Commitment Regulation Of Macromolecule Biosynthetic Process DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Negative Regulation Of Muscle Cell Differentiation Pituitary Gland Development Negative Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Biosynthetic Process Cardiac Muscle Cell Fate Commitment Central Nervous System Development Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Positive Regulation Of Macromolecule Biosynthetic Process Cardiac Muscle Cell Development Ventricular Cardiac Muscle Cell Development Cardiac Cell Development	Identical Protein Binding Protein Binding Spliceosomal Complex Structural Constituent Of Skin Epidermis RNA Splicing Intermediate Filament Regulation Of RNA Splicing Nucleic Acid Binding Keratin Filament Transcription Coactivator Activity MRNA Splicing, Via Spliceosome MRNA Processing Regulation Of MRNA Splicing, Via Spliceosome CD4 Receptor Binding RNA Splicing, Via Transesterification Reactions RNA Processing Regulation Of MRNA Processing Ribonucleoprotein Complex RNA Binding Positive Regulation Of Apoptotic Signaling Pathway
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