DNAL4 and FHL5

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		DNAL4	FHL5
Gene Name		dynein, axonemal, light chain 4	four and a half LIM domains 5
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Microtubule Plasma Membrane Cilium Dynein Complex	Nucleus
	Molecular Function	Motor Activity	Transcription Coactivator Activity Protein Binding Zinc Ion Binding
	Biological Process	Microtubule-based Process Metabolic Process Neurotrophin TRK Receptor Signaling Pathway	Positive Regulation Of Transcription From RNA Polymerase II Promoter
Pathways		Retrograde neurotrophin signalling Signalling by NGF NGF signalling via TRKA from the plasma membrane
Drugs
Diseases
GWAS			Coronary heart disease ( 22319020) Migraine ( 22683712)
Protein-Protein Interactions		9 interactors: CAMK2D DYNLL2 FHL5 GNA14 GPBP1 KRTAP10-3 NOTCH2NL SCTR TRIM54	12 interactors: COIL CREB1 CREM DNAL4 FHL2 FHL3 HOXA1 KIF17 SMAD1 SRF STX11 ZNF446
Entrez ID		10126	9457
HPRD ID		13239	05497
Ensembl ID		ENSG00000100246	ENSG00000112214
Uniprot IDs		O96015 Q6FGD0	Q5TD97
PDB IDs			1X68
Enriched GO Terms of Interacting Partners?		Synaptic Target Recognition Regulation Of Cardiac Muscle Cell Action Potential Involved In Regulation Of Contraction Cardiac Muscle Cell Contraction Regulation Of Generation Of L-type Calcium Current Positive Regulation Of Rac Protein Signal Transduction Regulation Of Histone Deacetylase Activity Regulation Of Cell Communication By Electrical Coupling Involved In Cardiac Conduction Negative Regulation Of Sodium Ion Transmembrane Transporter Activity Signal Transduction Negative Regulation Of Sodium Ion Transmembrane Transport Regulation Of Relaxation Of Cardiac Muscle Regulation Of Cardiac Muscle Cell Action Potential Regulation Of Organelle Organization Phospholipase C-activating Dopamine Receptor Signaling Pathway Regulation Of Relaxation Of Muscle Cellular Potassium Ion Homeostasis Cell Growth Involved In Cardiac Muscle Cell Development Signaling Cell Communication Regulation Of Cellular Process Negative Regulation Of Sodium Ion Transport Regulation Of Cell Communication By Electrical Coupling	Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Transcription, DNA-templated Transcription, DNA-templated Positive Regulation Of Macromolecule Biosynthetic Process Heart Trabecula Formation RNA Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Response To Organic Substance Positive Regulation Of Transcription From RNA Polymerase II Promoter Heart Trabecula Morphogenesis Cardiac Muscle Tissue Development RNA Metabolic Process Tube Development Trabecula Morphogenesis Multicellular Organismal Development Cell Differentiation Gene Expression Cognition Brain Development Artery Morphogenesis Striated Muscle Tissue Development Cellular Macromolecule Biosynthetic Process Head Development Macromolecule Biosynthetic Process Muscle Tissue Development Artery Development Positive Regulation Of Cellular Metabolic Process Cardiac Muscle Cell Development Cardiovascular System Development Transcription From RNA Polymerase II Promoter Abducens Nerve Formation Contractile Actin Filament Bundle Assembly Optokinetic Behavior Neurogenesis Developmental Process Mesoderm Formation Central Nervous System Development Mesoderm Morphogenesis System Development Cellular Response To Organic Substance Facial Nucleus Development Anatomical Structure Formation Involved In Morphogenesis Regulation Of Transcription, DNA-templated Single-organism Behavior Organ Development Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Pattern Specification Process Cardiac Muscle Cell Differentiation
Tagcloud ?			1p13 1p36 5x10 6q16 7p14 8q21 affecting ajap1 apoa1bp atp5b c7orf10 candidate fut9 loci locus matched meta migraine mmp16 near poorly stat6 subgroup susceptibility tbc1d7 trait tspan2 understood wide
Tagcloud (Difference) ?			1p13 1p36 5x10 6q16 7p14 8q21 affecting ajap1 apoa1bp atp5b c7orf10 candidate fut9 loci locus matched meta migraine mmp16 near poorly stat6 subgroup susceptibility tbc1d7 trait tspan2 understood wide
Tagcloud (Intersection) ?