MTCL2 and EFHC2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		MTCL2	EFHC2
Description		microtubule crosslinking factor 2	EF-hand domain containing 2
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Extracellular Region Extracellular Space Cytoplasm Golgi Apparatus Cytoskeleton Microtubule Membrane Midbody Extracellular Exosome	Cytoplasm Cytoskeleton Microtubule Axonemal Microtubule Cilium Motile Cilium Ciliary Basal Body Sperm Flagellum Cell Projection Axonemal A Tubule Inner Sheath
	Molecular Function	Protein Binding	Calcium Ion Binding Protein Binding
	Biological Process	Chromosome Segregation Insulin Receptor Signaling Pathway Regulation Of Autophagy Negative Regulation Of Gluconeogenesis Cell Division	Regulation Of Neuron Projection Development Flagellated Sperm Motility Cellular Response To Leukemia Inhibitory Factor
Pathways
Drugs
Diseases
GWAS			Body mass index and diastolic blood pressure (bivariate analysis) ( 33539483) Glaucoma (primary open-angle) ( 33627673) Mean arterial pressure ( 29403010)
Interacting Genes		15 interacting genes: AMOTL2 BHLHE40 EFHC2 FAM161A HDAC7 LZTS1 NECAB2 NUTM1 PLEKHA5 PPP1R13B RORB STX11 TFIP11 TSNAX ZNF20	100 interacting genes: - AASDHPPT ARHGEF5 ARMC7 ATOSB CABP2 CACNB4 CARD9 CCDC102B CCDC120 CCDC13 CCDC57 CCHCR1 CCNG2 CDKN2A CLIC3 COPE CPNE2 CPNE7 CYFIP1 DCLK1 DDX6 DGCR6 DRC7 EDC3 EFHC1 EGLN3 EMD ENKD1 ESRRG EXOC8 EXOSC5 FAM107A FAM124B FAM221B FBXL19 GEM GLYCTK GOLGA1 GPKOW GRB2 GYS1 HDAC4 HGS HNRNPLL INPP5J JAKMIP2 KANK2 KCTD7 KIF9 L3MBTL2 LMNB2 LMO2 LNX1 LONRF1 MAGOHB MAPK9 MID2 MISP MTCL2 MYLIP MYO5B NCDN NCK2 NDOR1 NEK6 NFKBID NME7 NR3C1 PBLD PHF1 PIBF1 PICK1 PLOD3 POLR1C PRPF18 PTK6 QARS1 RAD51D RCOR3 RECK RHOBTB3 RUNX1T1 SNRNP25 SPATA18 SPG21 STK16 TBC1D1 TBC1D22B TEKT4 TRIM42 TRIM50 TSSK3 TUBGCP4 TXK U2AF1 USP2 ZBTB16 ZFHX3 ZZZ3
Entrez ID		140710	80258
HPRD ID		18553	06540
Ensembl ID		ENSG00000149639	ENSG00000183690
Uniprot IDs		O94964 X6R3R3	Q5JST6
PDB IDs			2Z13 2Z14 7UNG 8J07
Enriched GO Terms of Interacting Partners?		A2A Adenosine Receptor Binding	Cytoplasm Protein Binding Protein Phosphorylation Cytoskeleton Regulation Of Podosome Assembly Phosphorylation Centrosome
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