MTCL2 and TSNAX

Number of citations of the paper that reports this interaction (PubMedID 33961781)
97

Data Source:
BioGRID (affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology)

		MTCL2	TSNAX
Description		microtubule crosslinking factor 2	translin associated factor X
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Extracellular Region Extracellular Space Cytoplasm Golgi Apparatus Cytoskeleton Microtubule Membrane Midbody Extracellular Exosome	Nucleus Nucleoplasm Cytoplasm Golgi Apparatus Cytosol Perinuclear Region Of Cytoplasm Endoribonuclease Complex
	Molecular Function	Protein Binding	DNA Binding Single-stranded DNA Binding RNA Binding RNA Endonuclease Activity Protein Binding A2A Adenosine Receptor Binding Sequence-specific DNA Binding Protein-containing Complex Binding Metal Ion Binding
	Biological Process	Chromosome Segregation Insulin Receptor Signaling Pathway Regulation Of Autophagy Negative Regulation Of Gluconeogenesis Cell Division	Spermatogenesis Cell Differentiation SiRNA Processing Regulatory NcRNA-mediated Post-transcriptional Gene Silencing
Pathways			Small interfering RNA (siRNA) biogenesis
Drugs
Diseases
GWAS			Chronic periodontitis (mean interproximal clinical attachment level) ( 27601451) Metabolite levels ( 23823483)
Interacting Genes		15 interacting genes: AMOTL2 BHLHE40 EFHC2 FAM161A HDAC7 LZTS1 NECAB2 NUTM1 PLEKHA5 PPP1R13B RORB STX11 TFIP11 TSNAX ZNF20	41 interacting genes: AIMP1 AKAP9 BEX3 BLOC1S5 C1D CARD9 CDK5RAP2 CEBPA CEP68 CKAP4 COG6 EMILIN1 GADD45G GOLGA3 GPATCH2 GRIPAP1 HMGB2 KCNE4 KRT31 LDB2 LDOC1 LZTS2 MECOM MRFAP1L1 MTCL2 NSMCE2 NTAQ1 PBXIP1 PRPF18 RALYL RFC5 SPRED2 SUN1 SYCE2 SYT17 TCF12 TCP11L1 TSN TSNAXIP1 UBE2I VPS28
Entrez ID		140710	7257
HPRD ID		18553	04270
Ensembl ID		ENSG00000149639	ENSG00000116918
Uniprot IDs		O94964 X6R3R3	Q99598
PDB IDs			3PJA 3QB5
Enriched GO Terms of Interacting Partners?		A2A Adenosine Receptor Binding
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