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ASB9 and HIF1AN
Number of citations of the paper that reports this interaction (PMID
16189514
)
699
Data Source:
HPRD
(two hybrid)
ASB9
HIF1AN
Gene Name
ankyrin repeat and SOCS box containing 9
hypoxia inducible factor 1, alpha subunit inhibitor
Image
Gene Ontology Annotations
Cellular Component
Mitochondrion
Nucleus
Nucleoplasm
Cytoplasm
Cytosol
Perinuclear Region Of Cytoplasm
Molecular Function
Protein Binding
Notch Binding
Iron Ion Binding
Protein Binding
Zinc Ion Binding
Oxidoreductase Activity, Acting On Paired Donors, With Incorporation Or Reduction Of Molecular Oxygen, 2-oxoglutarate As One Donor, And Incorporation Of One Atom Each Of Oxygen Into Both Donors
Oxygen Sensor Activity
Carboxylic Acid Binding
Peptidyl-histidine Dioxygenase Activity
Peptidyl-asparagine 3-dioxygenase Activity
Protein Homodimerization Activity
Cofactor Binding
NF-kappaB Binding
Ankyrin Repeat Binding
Biological Process
Protein Ubiquitination
Intracellular Signal Transduction
Positive Regulation Of Protein Catabolic Process
Transcription, DNA-templated
Peptidyl-histidine Hydroxylation
Peptidyl-aspartic Acid Hydroxylation
Peptidyl-asparagine Hydroxylation
Positive Regulation Of Myoblast Differentiation
Negative Regulation Of Notch Signaling Pathway
Oxidation-reduction Process
Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia
Negative Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia
Cellular Response To Hypoxia
Positive Regulation Of Vasculogenesis
Pathways
Antigen processing: Ubiquitination & Proteasome degradation
Class I MHC mediated antigen processing & presentation
Adaptive Immune System
Cellular response to hypoxia
Regulation of Hypoxia-inducible Factor (HIF) by oxygen
Oxygen-dependent asparagine hydroxylation of Hypoxia-inducible Factor Alpha
Drugs
Diseases
GWAS
Palmitoleic acid (16:1n-7) plasma levels (
23362303
)
Protein-Protein Interactions
4 interactors:
CKB
CKM
HIF1AN
UBE2D1
13 interactors:
ASB13
ASB4
ASB9
FBF1
FEM1B
HDAC1
HDAC2
HDAC3
HIF1A
INVS
NFKB1
UACA
VHL
Entrez ID
140462
55662
HPRD ID
06452
09426
Ensembl ID
ENSG00000102048
Uniprot IDs
Q96DX5
Q9NWT6
PDB IDs
3D9H
3ZKJ
1H2K
1H2L
1H2M
1H2N
1IZ3
1MZE
1MZF
1YCI
2CGN
2CGO
2ILM
2W0X
2WA3
2WA4
2XUM
2Y0I
2YC0
2YDE
3D8C
3KCX
3KCY
3OD4
3P3N
3P3P
4AI8
4B7E
4B7K
4BIO
Enriched GO Terms of Interacting Partners
?
Creatine Metabolic Process
Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia
Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress
Regulation Of DNA-templated Transcription In Response To Stress
Cellular Response To Hypoxia
Cellular Response To Decreased Oxygen Levels
Cellular Response To Oxygen Levels
Peptidyl-asparagine Hydroxylation
Phosphocreatine Biosynthetic Process
Peptidyl-histidine Hydroxylation
Peptidyl-aspartic Acid Hydroxylation
Negative Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia
Cellular Modified Amino Acid Metabolic Process
Alpha-amino Acid Metabolic Process
Response To Hypoxia
Cellular Chloride Ion Homeostasis
Chloride Ion Homeostasis
Cellular Nitrogen Compound Metabolic Process
Positive Regulation Of Vasculogenesis
Cellular Amino Acid Metabolic Process
Regulation Of Vasculogenesis
Nitrogen Compound Metabolic Process
Positive Regulation Of Myoblast Differentiation
Protein Hydroxylation
Negative Regulation Of Notch Signaling Pathway
Mitotic Spindle Assembly Checkpoint
Spindle Assembly Checkpoint
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Protein K48-linked Ubiquitination
Substantia Nigra Development
Mitotic Spindle Checkpoint
Negative Regulation Of Chromosome Segregation
Regulation Of Myoblast Differentiation
Anion Homeostasis
Spindle Checkpoint
Regulation Of Mitotic Sister Chromatid Separation
Negative Regulation Of Mitotic Nuclear Division
Regulation Of Mitotic Metaphase/anaphase Transition
Neural Nucleus Development
Negative Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle
Positive Regulation Of Ubiquitin-protein Ligase Activity Involved In Regulation Of Mitotic Cell Cycle Transition
Regulation Of Notch Signaling Pathway
TRIF-dependent Toll-like Receptor Signaling Pathway
Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Carboxylic Acid Metabolic Process
Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle
Negative Regulation Of Ubiquitin-protein Transferase Activity
Negative Regulation Of Proteasomal Protein Catabolic Process
MyD88-independent Toll-like Receptor Signaling Pathway
Toll-like Receptor 3 Signaling Pathway
Positive Regulation Of Receptor Biosynthetic Process
Regulation Of Receptor Biosynthetic Process
Histone H4 Deacetylation
Regulation Of Apoptotic Process
Regulation Of Cell Death
Histone H3 Deacetylation
Histone H3-K9 Modification
Histone Deacetylation
Negative Regulation Of Apoptotic Process
Neurotrophin TRK Receptor Signaling Pathway
Protein Deacetylation
Negative Regulation Of Programmed Cell Death
Neurotrophin Signaling Pathway
Negative Regulation Of Cell Death
Fungiform Papilla Formation
Circadian Regulation Of Gene Expression
Protein Ubiquitination
Fungiform Papilla Morphogenesis
Negative Regulation Of Signal Transduction
Protein Modification By Small Protein Conjugation
Fungiform Papilla Development
Eyelid Development In Camera-type Eye
Negative Regulation Of Signaling
Hair Follicle Placode Formation
Regulation Of Signal Transduction
Tongue Morphogenesis
Cellular Response To Stimulus
Positive Regulation Of Transcription, DNA-templated
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Signal Transduction
Epithelial Cell Maturation
Notch Signaling Pathway
Negative Regulation Of Intracellular Signal Transduction
Regulation Of Signaling
Positive Regulation Of Cell Differentiation
Protein Metabolic Process
Positive Regulation Of Macromolecule Biosynthetic Process
Cellular Protein Modification Process
Signaling
Positive Regulation Of Gene Expression
Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia
Cell Communication
Circadian Rhythm
Positive Regulation Of Cellular Biosynthetic Process
Positive Regulation Of Metabolic Process
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Tongue Development
Epithelial Cell Differentiation
Positive Regulation Of Cellular Metabolic Process
Epithelium Development
Tagcloud
?
bomb
coimmunoprecipitation
collated
cytoskeleton
defines
depicts
dissect
evolutionarily
fate
fih
interacted
interesting
mib
mib2
mind
notch
protease
ran
screens
summarized
trabid
traf
ubiquitin
ubiquitylate
ubiquitylation
usp1
usp9
zebrafish
zranb1
Tagcloud (Difference)
?
bomb
coimmunoprecipitation
collated
cytoskeleton
defines
depicts
dissect
evolutionarily
fate
fih
interacted
interesting
mib
mib2
mind
notch
protease
ran
screens
summarized
trabid
traf
ubiquitin
ubiquitylate
ubiquitylation
usp1
usp9
zebrafish
zranb1
Tagcloud (Intersection)
?