ASB9 and CKB

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
BioGRID (two hybrid, affinity chromatography technology)
HPRD (two hybrid)

		ASB9	CKB
Gene Name		ankyrin repeat and SOCS box containing 9	creatine kinase, brain
Image
Gene Ontology Annotations	Cellular Component	Mitochondrion	Mitochondrion Cytosol Extracellular Vesicular Exosome
	Molecular Function	Protein Binding	Creatine Kinase Activity Protein Binding ATP Binding
	Biological Process	Protein Ubiquitination Intracellular Signal Transduction Positive Regulation Of Protein Catabolic Process	Creatine Metabolic Process Phosphorylation Substantia Nigra Development Cellular Chloride Ion Homeostasis Cellular Nitrogen Compound Metabolic Process Small Molecule Metabolic Process
Pathways		Antigen processing: Ubiquitination & Proteasome degradation Class I MHC mediated antigen processing & presentation Adaptive Immune System	Metabolism of amino acids and derivatives Creatine metabolism
Drugs			Creatine
Diseases
GWAS
Protein-Protein Interactions		4 interactors: CKB CKM HIF1AN UBE2D1	12 interactors: ACD ASB9 CKM ILK MLH1 POT1 PPP1CA SERP2 TAB1 TERF1 TINF2 TRIM63
Entrez ID		140462	1152
HPRD ID		06452	00423
Ensembl ID		ENSG00000102048	ENSG00000166165
Uniprot IDs		Q96DX5	P12277
PDB IDs		3D9H 3ZKJ	3B6R 3DRB 3DRE
Enriched GO Terms of Interacting Partners?		Creatine Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Regulation Of DNA-templated Transcription In Response To Stress Cellular Response To Hypoxia Cellular Response To Decreased Oxygen Levels Cellular Response To Oxygen Levels Peptidyl-asparagine Hydroxylation Phosphocreatine Biosynthetic Process Peptidyl-histidine Hydroxylation Peptidyl-aspartic Acid Hydroxylation Negative Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Cellular Modified Amino Acid Metabolic Process Alpha-amino Acid Metabolic Process Response To Hypoxia Cellular Chloride Ion Homeostasis Chloride Ion Homeostasis Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Vasculogenesis Cellular Amino Acid Metabolic Process Regulation Of Vasculogenesis Nitrogen Compound Metabolic Process Positive Regulation Of Myoblast Differentiation Protein Hydroxylation Negative Regulation Of Notch Signaling Pathway Mitotic Spindle Assembly Checkpoint Spindle Assembly Checkpoint Negative Regulation Of Transcription From RNA Polymerase II Promoter Protein K48-linked Ubiquitination Substantia Nigra Development Mitotic Spindle Checkpoint Negative Regulation Of Chromosome Segregation Regulation Of Myoblast Differentiation Anion Homeostasis Spindle Checkpoint Regulation Of Mitotic Sister Chromatid Separation Negative Regulation Of Mitotic Nuclear Division Regulation Of Mitotic Metaphase/anaphase Transition Neural Nucleus Development Negative Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Positive Regulation Of Ubiquitin-protein Ligase Activity Involved In Regulation Of Mitotic Cell Cycle Transition Regulation Of Notch Signaling Pathway TRIF-dependent Toll-like Receptor Signaling Pathway Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Carboxylic Acid Metabolic Process Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Negative Regulation Of Ubiquitin-protein Transferase Activity Negative Regulation Of Proteasomal Protein Catabolic Process MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway	Negative Regulation Of Telomere Maintenance Via Telomerase Negative Regulation Of Telomere Maintenance Regulation Of Telomere Maintenance Via Telomerase Regulation Of Telomere Maintenance Negative Regulation Of DNA Metabolic Process Telomere Assembly Negative Regulation Of DNA Replication Telomere Maintenance Regulation Of Telomerase Activity Negative Regulation Of Chromosome Organization Regulation Of DNA Replication Telomere Maintenance Via Telomere Lengthening Regulation Of DNA Biosynthetic Process Regulation Of Chromosome Organization Protein Localization To Chromosome, Telomeric Region Telomere Capping Positive Regulation Of Telomerase Activity Telomere Maintenance Via Telomerase Negative Regulation Of Telomerase Activity Positive Regulation Of Telomere Maintenance Positive Regulation Of DNA Biosynthetic Process Positive Regulation Of DNA Metabolic Process Regulation Of Organelle Organization RNA-dependent DNA Replication Negative Regulation Of DNA Biosynthetic Process Chromosome Organization Protein Localization To Chromosome DNA Metabolic Process Positive Regulation Of Transferase Activity Cellular Component Assembly Negative Regulation Of Cellular Metabolic Process Regulation Of Metabolic Process Negative Regulation Of Transferase Activity Positive Regulation Of DNA Replication Negative Regulation Of Protein ADP-ribosylation Meiotic Metaphase I Plate Congression Positive Regulation Of Single-stranded Telomeric DNA Binding Positive Regulation Of DNA Strand Elongation Meiotic Spindle Midzone Assembly Phosphocreatine Biosynthetic Process Cell Aging Cellular Metabolic Process Positive Regulation Of Organelle Organization Regulation Of Protein ADP-ribosylation Negative Regulation Of Mitotic Recombination Negative Regulation Of Telomere Maintenance Via Semi-conservative Replication Telomere Formation Via Telomerase Telomeric Loop Formation Age-dependent Telomere Shortening Regulation Of Cellular Component Organization
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