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CLDN7 and NKG7
Number of citations of the paper that reports this interaction (PubMedID
32296183
)
50
Data Source:
BioGRID
(two hybrid)
CLDN7
NKG7
Description
claudin 7
natural killer cell granule protein 7
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Plasma Membrane
Bicellular Tight Junction
Membrane
Basolateral Plasma Membrane
Apicolateral Plasma Membrane
Lateral Plasma Membrane
Anchoring Junction
Lysosome
Plasma Membrane
Membrane
Cytolytic Granule
Cytolytic Granule Membrane
Molecular Function
Structural Molecule Activity
Protein Binding
Identical Protein Binding
Protein Binding
Biological Process
Cell Adhesion
Calcium-independent Cell-cell Adhesion Via Plasma Membrane Cell-adhesion Molecules
Bicellular Tight Junction Assembly
Natural Killer Cell Mediated Cytotoxicity Directed Against Tumor Cell Target
Inflammatory Response
Killing Of Cells Of Another Organism
CD4-positive, Alpha-beta T Cell Activation
Natural Killer Cell Mediated Cytotoxicity
Defense Response To Protozoan
Natural Killer Cell Degranulation
Positive Regulation Of Inflammatory Response
Granzyme-mediated Programmed Cell Death Signaling Pathway
Pathways
Tight junction interactions
Drugs
Diseases
GWAS
Birth weight (
27680694
31043758
)
FEV1 (
30804560
)
Lung function (FVC) (
30804560
)
Multiple sclerosis (
31604244
)
Offspring birth weight (
31043758
)
Neutrophil count (
27863252
32888494
)
Neutrophil percentage of white cells (
32888494
)
Interacting Genes
77 interacting genes:
AIG1
ANKRD46
APOD
AQP2
ASGR1
BCL2L2
BET1
BMP10
C3orf52
CD53
CD72
CLN6
CMTM5
CNIH1
COL4A5
CXCL16
CXCL9
CYB561A3
CYB561D2
CYB5B
CYBC1
EDDM3B
EMP3
EPCAM
ERG28
ERMP1
FAXDC2
FXYD6
GIMAP5
GLP1R
GPR37L1
HGD
IGFBP5
ITM2A
JAGN1
LAT
LEPROTL1
LPAR3
LSMEM2
MAL
MALL
MS4A13
NDUFB11
NIPAL4
NKG7
OLFM4
PGAP2
PLN
RHOXF2
RPRM
RTP2
SCAMP4
SCARF1
SEC22B
SERTM1
SLC38A7
SLC61A1
SYNE4
TJP1
TMEM100
TMEM11
TMEM128
TMEM140
TMEM147
TMEM44
TMEM60
TMEM97
TNF
TRARG1
TSPAN33
UBIAD1
UNC93B1
UPK1B
UPK2
VAMP3
VAMP5
VSTM1
49 interacting genes:
AGTRAP
AMIGO1
AQP6
ARL13B
ATP6AP2
BAMBI
CD53
CD79A
CLDN7
CLEC2D
CLEC4E
CLSTN3
CREB3
EBP
EDA2R
ERGIC3
FAM209A
FAM210B
FFAR2
FKBP7
FNDC9
GJA5
GORAB
GPX8
ISLR2
KLRC1
LHFPL5
LMNA
MFSD6
MGST3
MS4A3
MSR1
MUC1
OPRK1
PEX12
RAMP1
RNF24
SLC10A1
SLC18A2
SLC30A8
SLC35H1
STOM
STX1A
TLCD4
TMEM106C
TMEM130
TMEM139
TMEM80
TMEM88
Entrez ID
1366
4818
HPRD ID
07633
16188
Ensembl ID
ENSG00000181885
ENSG00000105374
Uniprot IDs
A0A384ME58
F5H496
O95471
A0A0B4J2A6
Q16617
PDB IDs
Enriched GO Terms of Interacting Partners
?
Membrane
Protein Binding
Endoplasmic Reticulum Membrane
Endoplasmic Reticulum
Plasma Membrane
Localization Within Membrane
Transmembrane Ascorbate Ferrireductase Activity
Membrane
Plasma Membrane
Protein Binding
Tagcloud
?
Tagcloud (Difference)
?
Tagcloud (Intersection)
?