IRAK1BP1 and TFCP2

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		IRAK1BP1	TFCP2
Description		interleukin 1 receptor associated kinase 1 binding protein 1	transcription factor CP2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm	Chromatin Nucleus Nucleoplasm Cytosol Protein-containing Complex
	Molecular Function	Protein Binding Signaling Adaptor Activity	Transcription Cis-regulatory Region Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Transcription Factor Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Immune Response Positive Regulation Of Canonical NF-kappaB Signal Transduction	Regulation Of Transcription By RNA Polymerase II MRNA Transcription By RNA Polymerase II Positive Regulation Of Transcription By RNA Polymerase II
Pathways
Drugs
Diseases
GWAS		Blood pressure measurement (high sodium and potassium intervention) ( 24165912) Blood pressure measurement (high sodium intervention) ( 24165912) Blood pressure measurement (low sodium intervention) ( 24165912) Cadmium levels ( 26025379) Daytime nap ( 33568662) Diastolic blood pressure x alcohol consumption interaction (2df test) ( 29912962) Late-onset Alzheimer's disease ( 27770636) LDL cholesterol levels x loop diuretics use interaction ( 31806883) Macular thickness ( 30535121) Sjögren's syndrome ( 24097067)
Interacting Genes		11 interacting genes: IRAK1 MISP PHF1 PRKAB2 RELA RIPPLY1 SCNM1 TFCP2 UFL1 USP20 ZNF410	73 interacting genes: ACAA1 ADPRH APBB1 ASAP3 BAG6 C19orf73 CA1 CAPN3 CASP8 CBX8 CDC73 COIL DNAJC5B DPH1 E2F8 EAF1 EIF5B EPHA10 FAM120C FANCL FARS2 FBXL18 FXR2 GPANK1 HAPLN2 HDAC1 HDAC2 IRAK1BP1 LDB3 LSM1 MAPK1 MAPK14 MAPK8 MOB3C MORF4L1 MRPL11 MRPL40 MVP NABP1 NEDD9 NFE4 NHSL2 NOM1 NPEPL1 PHF1 PHF21B PIMREG PITPNM1 PLCB1 POLL POLR3GL PPIG PPP1R1B PPP3R2 PSMD5 RBMS1 RNF2 RXRB SDCBP SHTN1 SIN3A STMN2 SUMO1 TCEA2 TDRD1 TLK1 TRAPPC12 TSPAN12 UBE2I YJU2 YY1 ZCCHC10 ZCCHC12
Entrez ID		134728	7024
HPRD ID		17157	01790
Ensembl ID		ENSG00000146243	ENSG00000135457
Uniprot IDs		Q5VVH5	Q12800
PDB IDs
Enriched GO Terms of Interacting Partners?		Canonical NF-kappaB Signal Transduction Antiviral Innate Immune Response Regulation Of Canonical NF-kappaB Signal Transduction Interleukin-1-mediated Signaling Pathway Protein Kinase Binding Positive Regulation Of Leukocyte Adhesion To Vascular Endothelial Cell Regulation Of DNA-binding Transcription Factor Activity Regulation Of Leukocyte Adhesion To Vascular Endothelial Cell Toll-like Receptor 4 Signaling Pathway Cell Surface Toll-like Receptor Signaling Pathway Toll-like Receptor Signaling Pathway Innate Immune Response Cell Surface Pattern Recognition Receptor Signaling Pathway Positive Regulation Of Leukocyte Cell-cell Adhesion Defense Response To Virus UFM1 Ligase Activity Positive Regulation Of Gliogenesis Positive Regulation Of Cell-cell Adhesion Response To Interleukin-1 Defense Response To Other Organism Positive Regulation Of NF-kappaB Transcription Factor Activity Negative Regulation Of Intracellular Signal Transduction Protein-containing Complex Innate Immune Response Activating Cell Surface Receptor Signaling Pathway Defense Response To Symbiont NF-kappaB P50/p65 Complex UFM1 Transferase Activity Negative Regulation Of Canonical NF-kappaB Signal Transduction Regulation Of Leukocyte Cell-cell Adhesion Cytoplasmic Pattern Recognition Receptor Signaling Pathway Regulation Of Metabolic Process Site Of Double-strand Break Regulation Of Gliogenesis Positive Regulation Of Schwann Cell Differentiation Response To Virus Negative Regulation Of Post-translational Protein Modification Response To Cobalamin Positive Regulation Of Reticulophagy Mitotic Spindle Astral Microtubule End Positive Regulation Of Metabolic Process Positive Regulation Of DNA-binding Transcription Factor Activity Response To Amino Acid Toll-like Receptor TLR6:TLR2 Signaling Pathway Regulation Of Schwann Cell Differentiation NF-kappaB Complex Prolactin Signaling Pathway Regulation Of Reticulophagy Postsynapse To Nucleus Signaling Pathway Protein K69-linked Ufmylation Somite Specification	Nucleus Sin3-type Complex Protein Binding Nucleoplasm DNA Damage Response MAP Kinase Activity Protein Lysine Delactylase Activity Fungiform Papilla Formation RING-like Zinc Finger Domain Binding Macromolecule Metabolic Process Protein Decrotonylase Activity Histone Decrotonylase Activity Stress-activated MAPK Cascade Chromatin Binding Chromatin Organization Stress-activated Protein Kinase Signaling Cascade Hair Follicle Placode Formation Negative Regulation Of Stem Cell Population Maintenance PcG Protein Complex Small Protein Activating Enzyme Binding Postsynaptic Cytosol Cellular Response To Stress Enzyme Binding Cellular Response To Dopamine Response To Dopamine Nucleic Acid Metabolic Process Negative Regulation Of RNA Metabolic Process Negative Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Macromolecule Metabolic Process Self Proteolysis Fibroblast Proliferation Histone Deacetylase Complex Histone Deacetylase Activity, Hydrolytic Mechanism Substrate-dependent Cell Migration, Cell Extension Negative Regulation Of Gene Expression, Epigenetic
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?