FAM168B and NEDD9

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		FAM168B	NEDD9
Description		family with sequence similarity 168 member B	neural precursor cell expressed, developmentally down-regulated 9
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Plasma Membrane Membrane Axon Cell Projection Perinuclear Region Of Cytoplasm Extracellular Exosome	Spindle Pole Immunological Synapse Nucleus Nucleoplasm Cytoplasm Golgi Apparatus Spindle Cytosol Cytoskeleton Plasma Membrane Focal Adhesion Cilium Cell Cortex Membrane Basolateral Plasma Membrane Lamellipodium Ciliary Basal Body Cell Projection Anchoring Junction Mitotic Spindle
	Molecular Function	Protein Binding	Protein Binding Protein Tyrosine Kinase Binding
	Biological Process		Cytoskeleton Organization Cell Adhesion Signal Transduction Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway Integrin-mediated Signaling Pathway Learning Or Memory Cell Migration Positive Regulation Of Cell Migration Negative Regulation Of Cell Migration Regulation Of Actin Cytoskeleton Organization Positive Regulation Of Osteoclast Differentiation Actin Filament Bundle Assembly Cell Division Positive Regulation Of Protein Tyrosine Kinase Activity Cilium Disassembly Lymphocyte Migration Into Lymphoid Organs Positive Regulation Of Lymphocyte Chemotaxis Positive Regulation Of Substrate Adhesion-dependent Cell Spreading Positive Regulation Of Dendritic Spine Maintenance Positive Regulation Of Protein Localization Positive Regulation Of Immunological Synapse Formation
Pathways
Drugs
Diseases
GWAS			Childhood dental caries in permanent teeth ( 29931343) Coronary artery disease ( 29212778) Diastolic blood pressure x smoking status (current vs non-current) interaction (1df test) ( 29455858) Diastolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) HIV-1 susceptibility ( 22174851) Macular thickness ( 30535121) Prostate cancer ( 25217961) Small cell lung carcinoma ( 28604730)
Interacting Genes		51 interacting genes: AGXT ARID5A BAG3 CAMK2A CCNK CSTF2 CSTF2T EGLN3 FAM168A FAM222B FOXH1 FOXI1 GLIS2 GPS2 HOXB9 HSF4 KRTAP26-1 LASP1 MED25 MSRB3 MYOZ3 NEDD9 OTX1 PATZ1 PITX1 POGZ POM121 PRR35 RAMAC RBFOX2 RHOXF2 ROR2 SAMD7 SAXO4 SNRPB SNRPC SPAG8 TCF7L2 TENT5B TIAL1 TLE5 TLX3 UBAP2 VENTX VEZF1 VGLL3 VPS37C WDR25 YPEL3 ZC3H10 ZIC1	70 interacting genes: ABL1 ACTMAP ANKS1A APP AURKA BANP BCAR1 BCAR3 CDC42EP2 CDH1 CHAT CRK CRKL DIMT1 DMRTB1 DOCK9 DPPA4 EEIG1 ELSPBP1 EXOSC8 FAM168B FOSB FYN FZR1 HOXA1 ID2 INCA1 ITCH KLHL20 KRT32 LCK LHX8 LYN MED19 MICAL1 NAB2 NBPF19 NCK1 NFKBIA NOTCH2NLA NOTCH3 PEX14 PIK3CA PIK3R3 PRAM1 PRR20A PTK2 PTK2B PTPN11 PTPN12 PXN RAPGEF1 RBPMS REL RFX6 SH2D3C SMAD1 SMAD2 SMAD3 SNAPIN TBX19 TCF3 TFCP2 TRAF2 TRIM23 TRIM27 TRIP6 WWOX ZNF76 ZYX
Entrez ID		130074	4739
HPRD ID		17295	11888
Ensembl ID		ENSG00000152102	ENSG00000111859
Uniprot IDs		A1KXE4	A0A087WUD2 Q14511
PDB IDs			2L81 5X3S
Enriched GO Terms of Interacting Partners?		Regulation Of Transcription By RNA Polymerase II Nucleus Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of DNA-templated Transcription Positive Regulation Of RNA Biosynthetic Process Nucleoplasm Sequence-specific Double-stranded DNA Binding Regulation Of Primary Metabolic Process Regulation Of Gene Expression Positive Regulation Of RNA Metabolic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Macromolecule Biosynthetic Process Myoblast Fate Commitment Regulation Of Macromolecule Metabolic Process DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Positive Regulation Of Macromolecule Metabolic Process Positive Regulation Of Biosynthetic Process Positive Regulation Of Metabolic Process Regulation Of Metabolic Process DNA Binding DNA-binding Transcription Factor Activity Negative Regulation Of RNA Metabolic Process Positive Regulation Of Protein Localization To Nucleus Chromatin Transcription Corepressor Activity Protein Binding Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Transcription By RNA Polymerase II RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Inner Ear Morphogenesis Transcription Regulator Complex MRNA Cleavage And Polyadenylation Specificity Factor Complex Transcription Cis-regulatory Region Binding U2-type Prespliceosome Negative Regulation Of Androgen Receptor Signaling Pathway Nuclear Retinoid X Receptor Binding Regulation Of Protein Localization To Nucleus U1 SnRNP Embryonic Morphogenesis	Enzyme-linked Receptor Protein Signaling Pathway Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway Phosphotyrosine Residue Binding Ephrin Receptor Binding Ephrin Receptor Signaling Pathway Cytosol Cell Surface Receptor Signaling Pathway Response To Growth Factor Antigen Receptor-mediated Signaling Pathway Cellular Response To Growth Factor Stimulus Positive Regulation Of Macromolecule Metabolic Process Immune Response-activating Cell Surface Receptor Signaling Pathway Epidermal Growth Factor Receptor Signaling Pathway Leukocyte Activation Cell Activation Positive Regulation Of Metabolic Process T Cell Receptor Signaling Pathway Cell Migration Response To Transforming Growth Factor Beta Signal Complex Assembly Positive Regulation Of Immune System Process Immune Response-regulating Cell Surface Receptor Signaling Pathway Non-membrane Spanning Protein Tyrosine Kinase Activity Immune Response-activating Signaling Pathway Positive Regulation Of RNA Biosynthetic Process ERBB Signaling Pathway Positive Regulation Of RNA Metabolic Process Positive Regulation Of DNA-templated Transcription Regulation Of Immune Response Lymphocyte Activation Intracellular Signaling Cassette Immune System Process Regulation Of Macromolecule Metabolic Process Regulation Of Gene Expression Intracellular Signal Transduction Endothelin Receptor Signaling Pathway Immune Response-regulating Signaling Pathway Activation Of Immune Response Integrin-mediated Signaling Pathway DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Regulation Of Macromolecule Biosynthetic Process Cell Motility Cellular Response To Transforming Growth Factor Beta Stimulus Positive Regulation Of Nucleobase-containing Compound Metabolic Process Cytoplasm Regulation Of Immune System Process Fc-gamma Receptor Signaling Pathway Nucleus Signal Transduction Regulation Of Metabolic Process
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