FAM168B and SPAG8

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		FAM168B	SPAG8
Description		family with sequence similarity 168 member B	sperm associated antigen 8
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Plasma Membrane Membrane Axon Cell Projection Perinuclear Region Of Cytoplasm Extracellular Exosome	Acrosomal Vesicle Male Germ Cell Nucleus Nucleus Nucleoplasm Cytoplasm Microtubule Organizing Center Spindle Cytosol Cytoskeleton Axonemal Microtubule Cilium Membrane Cytoplasmic Vesicle Motile Cilium Sperm Flagellum Cell Projection Axonemal A Tubule Inner Sheath
	Molecular Function	Protein Binding	Protein Binding Microtubule Binding
	Biological Process		Spermatogenesis Single Fertilization Cell Differentiation Flagellated Sperm Motility Positive Regulation Of Transcription By RNA Polymerase II
Pathways
Drugs
Diseases
GWAS			Brain morphology (MOSTest) ( 32665545)
Interacting Genes		51 interacting genes: AGXT ARID5A BAG3 CAMK2A CCNK CSTF2 CSTF2T EGLN3 FAM168A FAM222B FOXH1 FOXI1 GLIS2 GPS2 HOXB9 HSF4 KRTAP26-1 LASP1 MED25 MSRB3 MYOZ3 NEDD9 OTX1 PATZ1 PITX1 POGZ POM121 PRR35 RAMAC RBFOX2 RHOXF2 ROR2 SAMD7 SAXO4 SNRPB SNRPC SPAG8 TCF7L2 TENT5B TIAL1 TLE5 TLX3 UBAP2 VENTX VEZF1 VGLL3 VPS37C WDR25 YPEL3 ZC3H10 ZIC1	87 interacting genes: ACTMAP ARMC5 B9D2 BATF2 CARM1 CCDC120 CCNC CDC23 CFP CSTF2 CSTF2T CTAG1A CTAG1B DMRT3 DOK3 DTX2 DYNLL2 EGFL7 FAM168B GIGYF1 GLYCTK GPSM3 HR INCA1 INTS11 JMJD4 KDM3B KLHL32 KRT34 KRTAP10-8 KRTAP11-1 KRTAP13-3 KRTAP15-1 KRTAP19-2 KRTAP19-6 KRTAP19-7 KRTAP21-2 KRTAP26-1 KRTAP3-1 KRTAP6-2 KRTAP7-1 LASP1 MEOX1 METTL15 MGAT5B NEDD4L NHLRC4 NSD3 NUDT21 PATZ1 PEF1 PFDN5 PHF1 PITX1 PLA2G10 PRMT1 PRMT2 PRMT5 PRR35 RAN RBP3 RIPK4 RNF125 RUSC1 SERGEF SMUG1 SMYD1 SNRPB SNRPC SYNGAP1 TEKT3 TEKT5 TENT5B TRIB3 TRIM42 TSC1 TTC23 UBAP2 UBQLN1 UBQLN4 USP2 VPS37C YPEL3 ZBTB32 ZIC1 ZNF34 ZNF581
Entrez ID		130074	26206
HPRD ID		17295	12039
Ensembl ID		ENSG00000152102	ENSG00000137098
Uniprot IDs		A1KXE4	A0A140VJV0 Q99932
PDB IDs			7UNG 8J07
Enriched GO Terms of Interacting Partners?		Regulation Of Transcription By RNA Polymerase II Nucleus Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of DNA-templated Transcription Positive Regulation Of RNA Biosynthetic Process Nucleoplasm Sequence-specific Double-stranded DNA Binding Regulation Of Primary Metabolic Process Regulation Of Gene Expression Positive Regulation Of RNA Metabolic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Macromolecule Biosynthetic Process Myoblast Fate Commitment Regulation Of Macromolecule Metabolic Process DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Positive Regulation Of Macromolecule Metabolic Process Positive Regulation Of Biosynthetic Process Positive Regulation Of Metabolic Process Regulation Of Metabolic Process DNA Binding DNA-binding Transcription Factor Activity Negative Regulation Of RNA Metabolic Process Positive Regulation Of Protein Localization To Nucleus Chromatin Transcription Corepressor Activity Protein Binding Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Transcription By RNA Polymerase II RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Inner Ear Morphogenesis Transcription Regulator Complex MRNA Cleavage And Polyadenylation Specificity Factor Complex Transcription Cis-regulatory Region Binding U2-type Prespliceosome Negative Regulation Of Androgen Receptor Signaling Pathway Nuclear Retinoid X Receptor Binding Regulation Of Protein Localization To Nucleus U1 SnRNP Embryonic Morphogenesis	Intermediate Filament Protein-arginine N-methyltransferase Activity Protein Binding Histone Methyltransferase Activity Protein-arginine Omega-N Asymmetric Methyltransferase Activity Methylation Methyltransferase Activity Methylosome Protein Methylation Histone Arginine N-methyltransferase Activity MRNA Cleavage And Polyadenylation Specificity Factor Complex Keratin Filament Histone H3K9me/H3K9me2 Demethylase Activity Histone H3 Methyltransferase Activity Histone H4R3 Methyltransferase Activity Peptidyl-arginine Methylation Macromolecule Methylation
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