SPAG8 and ARMC5

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		SPAG8	ARMC5
Description		sperm associated antigen 8	armadillo repeat containing 5
Image			No pdb structure
GO Annotations	Cellular Component	Acrosomal Vesicle Male Germ Cell Nucleus Nucleus Nucleoplasm Cytoplasm Microtubule Organizing Center Spindle Cytosol Cytoskeleton Axonemal Microtubule Cilium Membrane Cytoplasmic Vesicle Motile Cilium Sperm Flagellum Cell Projection Axonemal A Tubule Inner Sheath	Chromatin Nucleus Nucleoplasm Chromosome Cytoplasm Cytosol Focal Adhesion Membrane Cul3-RING Ubiquitin Ligase Complex
	Molecular Function	Protein Binding Microtubule Binding	Protein Binding Ubiquitin-like Ligase-substrate Adaptor Activity
	Biological Process	Spermatogenesis Single Fertilization Cell Differentiation Flagellated Sperm Motility Positive Regulation Of Transcription By RNA Polymerase II	In Utero Embryonic Development Mesoderm Formation Transcription By RNA Polymerase II Transcription Elongation By RNA Polymerase II Gastrulation Anatomical Structure Morphogenesis Hemopoiesis Adrenal Cortex Development T Cell Proliferation Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process CD4-positive, Alpha-beta T Cell Differentiation Regulation Of Steroid Biosynthetic Process Defense Response To Virus RNA Polymerase II Transcription Initiation Surveillance
Pathways
Drugs
Diseases
GWAS		Brain morphology (MOSTest) ( 32665545)
Interacting Genes		87 interacting genes: ACTMAP ARMC5 B9D2 BATF2 CARM1 CCDC120 CCNC CDC23 CFP CSTF2 CSTF2T CTAG1A CTAG1B DMRT3 DOK3 DTX2 DYNLL2 EGFL7 FAM168B GIGYF1 GLYCTK GPSM3 HR INCA1 INTS11 JMJD4 KDM3B KLHL32 KRT34 KRTAP10-8 KRTAP11-1 KRTAP13-3 KRTAP15-1 KRTAP19-2 KRTAP19-6 KRTAP19-7 KRTAP21-2 KRTAP26-1 KRTAP3-1 KRTAP6-2 KRTAP7-1 LASP1 MEOX1 METTL15 MGAT5B NEDD4L NHLRC4 NSD3 NUDT21 PATZ1 PEF1 PFDN5 PHF1 PITX1 PLA2G10 PRMT1 PRMT2 PRMT5 PRR35 RAN RBP3 RIPK4 RNF125 RUSC1 SERGEF SMUG1 SMYD1 SNRPB SNRPC SYNGAP1 TEKT3 TEKT5 TENT5B TRIB3 TRIM42 TSC1 TTC23 UBAP2 UBQLN1 UBQLN4 USP2 VPS37C YPEL3 ZBTB32 ZIC1 ZNF34 ZNF581	10 interacting genes: CNOT2 COL8A1 ENKD1 GLYCTK MKRN3 PRR35 SPAG8 TLX3 USHBP1 USP7
Entrez ID		26206	79798
HPRD ID		12039	07809
Ensembl ID		ENSG00000137098	ENSG00000140691
Uniprot IDs		A0A140VJV0 Q99932	B4DH27 B4DIU9 J3KQ26 Q96C12
PDB IDs		7UNG 8J07
Enriched GO Terms of Interacting Partners?		Intermediate Filament Protein-arginine N-methyltransferase Activity Protein Binding Histone Methyltransferase Activity Protein-arginine Omega-N Asymmetric Methyltransferase Activity Methylation Methyltransferase Activity Methylosome Protein Methylation Histone Arginine N-methyltransferase Activity MRNA Cleavage And Polyadenylation Specificity Factor Complex Keratin Filament Histone H3K9me/H3K9me2 Demethylase Activity Histone H3 Methyltransferase Activity Histone H4R3 Methyltransferase Activity Peptidyl-arginine Methylation Macromolecule Methylation
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