SPAG8 and B9D2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		SPAG8	B9D2
Description		sperm associated antigen 8	B9 domain containing 2
Image			No pdb structure
GO Annotations	Cellular Component	Acrosomal Vesicle Male Germ Cell Nucleus Nucleus Nucleoplasm Cytoplasm Microtubule Organizing Center Spindle Cytosol Cytoskeleton Axonemal Microtubule Cilium Membrane Cytoplasmic Vesicle Motile Cilium Sperm Flagellum Cell Projection Axonemal A Tubule Inner Sheath	Nucleus Cytoplasm Centrosome Cytosol Cytoskeleton Cilium Membrane MKS Complex Ciliary Basal Body Cell Projection
	Molecular Function	Protein Binding Microtubule Binding	Protein Binding Gamma-tubulin Binding
	Biological Process	Spermatogenesis Single Fertilization Cell Differentiation Flagellated Sperm Motility Positive Regulation Of Transcription By RNA Polymerase II	Cell Projection Organization Cilium Assembly
Pathways			Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion Anchoring of the basal body to the plasma membrane RHO GTPases Activate Formins Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS		Brain morphology (MOSTest) ( 32665545)	Colorectal cancer ( 24836286) Colorectal cancer or advanced adenoma ( 30510241) Coronary artery disease ( 29212778 32469254) Preterm birth (maternal effect) ( 28877031) Pulse pressure ( 27841878)
Interacting Genes		87 interacting genes: ACTMAP ARMC5 B9D2 BATF2 CARM1 CCDC120 CCNC CDC23 CFP CSTF2 CSTF2T CTAG1A CTAG1B DMRT3 DOK3 DTX2 DYNLL2 EGFL7 FAM168B GIGYF1 GLYCTK GPSM3 HR INCA1 INTS11 JMJD4 KDM3B KLHL32 KRT34 KRTAP10-8 KRTAP11-1 KRTAP13-3 KRTAP15-1 KRTAP19-2 KRTAP19-6 KRTAP19-7 KRTAP21-2 KRTAP26-1 KRTAP3-1 KRTAP6-2 KRTAP7-1 LASP1 MEOX1 METTL15 MGAT5B NEDD4L NHLRC4 NSD3 NUDT21 PATZ1 PEF1 PFDN5 PHF1 PITX1 PLA2G10 PRMT1 PRMT2 PRMT5 PRR35 RAN RBP3 RIPK4 RNF125 RUSC1 SERGEF SMUG1 SMYD1 SNRPB SNRPC SYNGAP1 TEKT3 TEKT5 TENT5B TRIB3 TRIM42 TSC1 TTC23 UBAP2 UBQLN1 UBQLN4 USP2 VPS37C YPEL3 ZBTB32 ZIC1 ZNF34 ZNF581	8 interacting genes: ALKBH7 P4HA3 PLEKHA7 QARS1 SAXO4 SPAG8 TLX3 VPS25
Entrez ID		26206	80776
HPRD ID		12039	14613
Ensembl ID		ENSG00000137098	ENSG00000123810
Uniprot IDs		A0A140VJV0 Q99932	Q9BPU9
PDB IDs		7UNG 8J07
Enriched GO Terms of Interacting Partners?		Intermediate Filament Protein-arginine N-methyltransferase Activity Protein Binding Histone Methyltransferase Activity Protein-arginine Omega-N Asymmetric Methyltransferase Activity Methylation Methyltransferase Activity Methylosome Protein Methylation Histone Arginine N-methyltransferase Activity MRNA Cleavage And Polyadenylation Specificity Factor Complex Keratin Filament Histone H3K9me/H3K9me2 Demethylase Activity Histone H3 Methyltransferase Activity Histone H4R3 Methyltransferase Activity Peptidyl-arginine Methylation Macromolecule Methylation
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