CARD10

Gene Name		caspase recruitment domain family, member 10
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm CBM Complex
	Molecular Function	Protein Binding Receptor Signaling Complex Scaffold Activity
	Biological Process	Protein Complex Assembly Activation Of NF-kappaB-inducing Kinase Activity Regulation Of Apoptotic Process
Pathways
Drugs
Diseases
GWAS		Optic disc parameters ( 21307088)
Protein-protein Interactions		4 interactors: ATXN7 BCL10 IKBKG KLHL12
Entrez ID		29775
HPRD ID		06233
Ensembl ID		ENSG00000100065
Uniprot IDs		Q8NC81 Q9BWT7
PDB IDs
Enriched GO Terms of Interacting Partners?		Toll-like Receptor Signaling Pathway T Cell Receptor Signaling Pathway Positive Regulation Of NF-kappaB Transcription Factor Activity Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Regulation Of Signal Transduction Antigen Receptor-mediated Signaling Pathway Activation Of Innate Immune Response Regulation Of Signaling Positive Regulation Of Mast Cell Cytokine Production Lymphotoxin A Biosynthetic Process Interleukin-6 Biosynthetic Process Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of Innate Immune Response Negative Regulation Of Signal Transduction Establishment Of Vesicle Localization Vesicle Localization Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Negative Regulation Of Signaling Fc-epsilon Receptor Signaling Pathway Regulation Of I-kappaB Kinase/NF-kappaB Signaling Negative Regulation Of Mature B Cell Apoptotic Process Regulation Of Innate Immune Response Regulation Of Phosphorylation Positive Regulation Of Transcription, DNA-templated Fc Receptor Signaling Pathway Immune Response-activating Cell Surface Receptor Signaling Pathway Interleukin-6 Production Regulation Of Phosphorus Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Negative Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Establishment Of Organelle Localization Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Interleukin-8 Biosynthetic Process Positive Regulation Of Cytokine Production B Cell Apoptotic Process Immune Response-regulating Cell Surface Receptor Signaling Pathway Negative Regulation Of B Cell Apoptotic Process Organelle Localization Regulation Of Interleukin-8 Biosynthetic Process Immune Response-regulating Signaling Pathway T Cell Apoptotic Process Regulation Of Cytokine Production Regulation Of B Cell Apoptotic Process Histone Deubiquitination COPII Vesicle Coating Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway COPII-coated Vesicle Budding
Tagcloud ?		100nm 24h 26s 4t1 avenues bortezomib controversial dffb entirely folding grp78 ingenuity ipa label lc modulated myeloma noxa nucleic proteasomal proteasome proteolytic psmd14 puma sequestosome tceb2 top traf3 trp53bp2