CARD10 and SEMA3B

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CARD10	SEMA3B
Description		caspase recruitment domain family member 10	semaphorin 3B
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Immunological Synapse Cytoplasm CBM Complex	Extracellular Region Endoplasmic Reticulum Plasma Membrane Extracellular Matrix
	Molecular Function	Protein Binding Signaling Receptor Complex Adaptor Activity	Protein Binding Semaphorin Receptor Binding Neuropilin Binding Chemorepellent Activity
	Biological Process	Activation Of NF-kappaB-inducing Kinase Activity Positive Regulation Of Macromolecule Metabolic Process Regulation Of Apoptotic Process Positive Regulation Of Canonical NF-kappaB Signal Transduction Regulation Of Immune Response Protein-containing Complex Assembly Negative Regulation Of Cell Migration Involved In Sprouting Angiogenesis Positive Regulation Of Protein Localization To Nucleus	Neural Crest Cell Migration Cell-cell Signaling Axon Guidance Positive Regulation Of Cell Migration Negative Chemotaxis Chemorepulsion Of Axon Semaphorin-plexin Signaling Pathway
Pathways
Drugs
Diseases
GWAS		Autoimmune hepatitis type-1 ( 24768677) Low vWF levels ( 26486471) Optic disc area ( 21307088 25631615 28073927 31798171) Optic disc size ( 31809533) Refractive error ( 32231278) Vertical cup-disc ratio ( 25241763 28073927) Vertical cup-disc ratio (adjusted for vertical disc diameter) ( 31959993) Vertical cup-disc ratio (multi-trait analysis) ( 31959993)	Obese vs. thin ( 30677029) Sleep duration (short sleep) ( 30846698) Waist circumference adjusted for body mass index ( 34021172)
Interacting Genes		105 interacting genes: ATXN7 BAHD1 BCL10 BCL6B C8orf48 CARD9 CATSPER1 CBX8 CCDC116 CCDC187 CDC37 CEP95 CHIC2 CNNM3 CWF19L2 CXCL16 CYSRT1 DHX57 DOCK2 DRC4 DUSP26 FAM47B FOXD4L3 GADD45GIP1 GFAP GIPC1 GPATCH2L GSE1 GSTP1 HBZ HOXB9 IKBKG IL16 JOSD1 KANK2 KDM1A KEAP1 KLHL12 KRT75 KRTAP10-8 KRTAP12-3 KRTAP26-1 KRTAP9-2 KRTAP9-3 LENG1 MAGOHB METTL17 MITD1 MYPOP NME7 OLIG3 PIBF1 PKP1 PNKP PRDM14 PRPF18 PRPF3 PRR35 PTCD1 PTGDS RIN1 SCNM1 SEMA3B SPATA18 SPMIP2 TBC1D22B TBC1D26 TFAP2D TMEM43 TRIM27 TRIM41 USP54 UTP14C ZBTB26 ZFP1 ZNF10 ZNF12 ZNF165 ZNF180 ZNF202 ZNF223 ZNF239 ZNF250 ZNF285 ZNF286A ZNF32 ZNF329 ZNF366 ZNF414 ZNF415 ZNF439 ZNF440 ZNF524 ZNF552 ZNF559 ZNF564 ZNF575 ZNF581 ZNF587 ZNF613 ZNF670 ZNF775 ZNF80 ZNF837 ZSCAN25	23 interacting genes: BOLL CARD10 CREBBP CYSRT1 HSF2BP KPRP KRTAP1-1 KRTAP10-8 KRTAP10-9 KRTAP12-2 KRTAP19-5 KRTAP5-9 MDFI NAA10 NBPF19 NOTCH2NLA NRP1 NRP2 PAK6 PICK1 RBPMS2 SEMA3A TRIP13
Entrez ID		29775	7869
HPRD ID		06233	03179
Ensembl ID		ENSG00000100065	ENSG00000012171
Uniprot IDs		Q9BWT7	A0A0C4DGV8 B4DEK9 Q13214 Q6PI51
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Transcription By RNA Polymerase II Regulation Of RNA Metabolic Process DNA Binding Zinc Ion Binding Regulation Of Nucleobase-containing Compound Metabolic Process RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Regulation Of Primary Metabolic Process Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Regulation Of Macromolecule Metabolic Process Protein Binding Regulation Of Metabolic Process Nucleus Intermediate Filament Metal Ion Binding DNA-binding Transcription Factor Activity Keratin Filament RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding Negative Regulation Of Transcription By RNA Polymerase II Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Metabolic Process Negative Regulation Of RNA Biosynthetic Process Identical Protein Binding CBM Complex	Sympathetic Neuron Projection Guidance Trigeminal Nerve Structural Organization Neural Crest Cell Migration Involved In Autonomic Nervous System Development Sympathetic Neuron Projection Extension Intermediate Filament Branchiomotor Neuron Axon Guidance Facial Nerve Structural Organization Sympathetic Ganglion Development Axon Extension Involved In Axon Guidance Ganglion Development Vestibulocochlear Nerve Structural Organization Anatomical Structure Arrangement Dorsal Root Ganglion Morphogenesis Sensory Neuron Axon Guidance Facioacoustic Ganglion Development Neuron Projection Arborization Ventral Trunk Neural Crest Cell Migration Neuron Projection Extension Basal Dendrite Arborization Basal Dendrite Morphogenesis Motor Neuron Axon Guidance Trigeminal Ganglion Development Cranial Ganglion Development Trunk Neural Crest Cell Migration Developmental Cell Growth Semaphorin-plexin Signaling Pathway Gonadotrophin-releasing Hormone Neuronal Migration To The Hypothalamus Developmental Growth Involved In Morphogenesis Axon Extension Vascular Endothelial Growth Factor Receptor Activity Female Meiosis I Hypothalamus Cell Migration Neural Crest Cell Migration Mesenchymal Cell Migration Axonogenesis Involved In Innervation N-terminal Protein Amino Acid Acetylation Dendrite Arborization Semaphorin Receptor Activity Semaphorin Receptor Complex Regulation Of Axon Extension Involved In Axon Guidance Sympathetic Nervous System Development Keratin Filament Identical Protein Binding Acetyltransferase Activity Tissue Development Vascular Endothelial Growth Factor Signaling Pathway Female Meiotic Nuclear Division Developmental Process Male Meiosis I Outflow Tract Septum Morphogenesis
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