COL4A6 and FBLN2

Number of citations of the paper that reports this interaction (PMID 7500359)
18

Data Source:
HPRD (in vivo)

		COL4A6	FBLN2
Gene Name		collagen, type IV, alpha 6	fibulin 2
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Region Collagen Type IV Trimer Endoplasmic Reticulum Lumen	Extracellular Region Proteinaceous Extracellular Matrix Extracellular Matrix Vesicle Extracellular Vesicular Exosome
	Molecular Function	Extracellular Matrix Structural Constituent	Extracellular Matrix Structural Constituent Calcium Ion Binding Extracellular Matrix Binding
	Biological Process	Cell Adhesion Extracellular Matrix Disassembly Extracellular Matrix Organization Collagen Catabolic Process	Positive Regulation Of Cell-substrate Adhesion Extracellular Matrix Organization
Pathways		Collagen formation Laminin interactions Collagen degradation ECM proteoglycans Anchoring fibril formation Integrin cell surface interactions Non-integrin membrane-ECM interactions Collagen biosynthesis and modifying enzymes Degradation of the extracellular matrix Assembly of collagen fibrils and other multimeric structures	Molecules associated with elastic fibres Elastic fibre formation
Drugs
Diseases
GWAS			Bipolar disorder (mood-incongruent) ( 23092984)
Protein-Protein Interactions		10 interactors: APP CD93 DCN FBLN2 FN1 HABP2 MATN2 MMP9 OSM SERPINE2	22 interactors: ACAN ATN1 BCAN COL18A1 COL4A1 COL4A2 COL4A3 COL4A4 COL4A5 COL4A6 ELN FBN1 FN1 HSPG2 ITGB3 LAMA1 LAMA5 LAMC2 NID1 PRELP VCAN ZNF408
Entrez ID		1288	2199
HPRD ID		02364	00630
Ensembl ID		ENSG00000197565	ENSG00000163520
Uniprot IDs		F5H851 Q14031 Q9BS57	F5H1F3 P98095 Q86V58 Q9Y3V7
PDB IDs
Enriched GO Terms of Interacting Partners?		Extracellular Matrix Organization Extracellular Structure Organization Response To Wounding Extracellular Matrix Disassembly Wound Healing Regulation Of Growth Endodermal Cell Differentiation Nervous System Development Cell Morphogenesis Involved In Differentiation Peptide Cross-linking Anatomical Structure Morphogenesis Mating Generation Of Neurons Endoderm Formation Neurogenesis System Development Platelet Degranulation Seminal Vesicle Epithelium Development Dendrite Regeneration Response To External Stimulus Axon Guidance Negative Regulation Of Transport Regulation Of Peptidase Activity Endoderm Development Blood Coagulation Hemostasis Cell Morphogenesis Negative Regulation Of Ion Transport Response To Abiotic Stimulus Single-organism Behavior Multicellular Organismal Development Mating Plug Formation Synaptic Growth At Neuromuscular Junction Cell Adhesion Anatomical Structure Development Secretion By Cell Immune System Process Response To Stress Axonogenesis Locomotion Collateral Sprouting In Absence Of Injury Tyrosine Phosphorylation Of Stat1 Protein Tyrosine Phosphorylation Of Stat5 Protein Formation Of Primary Germ Layer Axon Development Reproductive Process Regulation Of Body Fluid Levels Dendrite Development Cell Morphogenesis Involved In Neuron Differentiation Behavior	Extracellular Matrix Disassembly Extracellular Matrix Organization Extracellular Structure Organization Collagen Catabolic Process Collagen Metabolic Process Multicellular Organismal Macromolecule Metabolic Process Multicellular Organismal Metabolic Process Anatomical Structure Development System Development Developmental Process Multicellular Organismal Development Cell Adhesion Cell Morphogenesis Involved In Differentiation Glycosaminoglycan Catabolic Process Cardiovascular System Development Blood Vessel Morphogenesis Locomotion Catabolic Process Blood Vessel Development Cell Morphogenesis Nervous System Development Angiogenesis Vasculature Development Movement Of Cell Or Subcellular Component Anatomical Structure Morphogenesis Glycosaminoglycan Biosynthetic Process Axon Guidance Tissue Development Cell-substrate Junction Assembly Cell Development Organ Development Axonogenesis Glomerular Basement Membrane Development Renal System Development Cell Projection Morphogenesis Glycosaminoglycan Metabolic Process Axon Development Cell Part Morphogenesis Cell Morphogenesis Involved In Neuron Differentiation Chemotaxis Urogenital System Development Pathogenesis Neuron Projection Morphogenesis Cell Differentiation Proteoglycan Metabolic Process Cell Projection Organization Neuron Projection Development Retinal Blood Vessel Morphogenesis Kidney Development Neurogenesis
Tagcloud ?		aiming alport ats comprising concepts contiguous deletion deletions distally encompassing epidemiology exon exons extending families hereditary leiomyomatosis ligation mapped multicentric multiplex nephropathy oligo portugal proximally rarely segregated spanning	3p 3p24 anonymous arrayed candidate chromosomal closely colocation d3s1585 excluded fibulin generated intragenic linkage locus lod map marfan marker markers matrix mfs2 p25 placed point polymorphic polymorphisms scores sequencing
Tagcloud (Difference) ?		aiming alport ats comprising concepts contiguous deletion deletions distally encompassing epidemiology exon exons extending families hereditary leiomyomatosis ligation mapped multicentric multiplex nephropathy oligo portugal proximally rarely segregated spanning	3p 3p24 anonymous arrayed candidate chromosomal closely colocation d3s1585 excluded fibulin generated intragenic linkage locus lod map marfan marker markers matrix mfs2 p25 placed point polymorphic polymorphisms scores sequencing
Tagcloud (Intersection) ?