COL4A5 and ANXA7

Number of citations of the paper that reports this interaction (PMID 21900206)
27

Data Source:
BioGRID (two hybrid)

		COL4A5	ANXA7
Gene Name		collagen, type IV, alpha 5	annexin A7
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Region Collagen Type IV Trimer Basal Lamina Endoplasmic Reticulum Lumen Neuromuscular Junction	Nucleus Nuclear Envelope Endoplasmic Reticulum Membrane Cytosol Plasma Membrane Membrane Chromaffin Granule Membrane Extracellular Vesicular Exosome
	Molecular Function	Extracellular Matrix Structural Constituent	Integrin Binding Calcium Ion Binding Protein Binding Calcium-dependent Phospholipid Binding Poly(A) RNA Binding Calcium-dependent Protein Binding
	Biological Process	Axon Guidance Neuromuscular Junction Development Extracellular Matrix Disassembly Extracellular Matrix Organization Collagen Catabolic Process	Cellular Calcium Ion Homeostasis Autophagy Hemostasis Cell Proliferation Regulation Of Cell Shape Response To Salt Stress Cellular Water Homeostasis Negative Regulation Of Gene Expression Response To Organic Cyclic Compound Epithelial Cell Differentiation Social Behavior Response To Calcium Ion Membrane Fusion
Pathways		Signaling by PDGF NCAM1 interactions Collagen formation Axon guidance Collagen degradation Anchoring fibril formation Non-integrin membrane-ECM interactions Degradation of the extracellular matrix Assembly of collagen fibrils and other multimeric structures Laminin interactions ECM proteoglycans Integrin cell surface interactions Collagen biosynthesis and modifying enzymes NCAM signaling for neurite out-growth
Drugs
Diseases
GWAS
Protein-Protein Interactions		18 interactors: ANTXR2 ANXA7 APP CD93 CDKN1A DAZAP2 DCN FBLN2 FN1 HABP2 MATN2 MMP9 NR1H2 OSM RNF10 SERPINE2 SMN1 TK1	108 interactors: A1BG A2M ACTB ACTL6B ADAMTS10 ANGPT2 APC APLP1 ATP5B ATP6V1A ATXN3 BAG6 C14orf1 CCDC90B CCT7 CDK4 CELF3 CENPB CHGB CLEC3B COL11A2 COL4A2 COL4A5 COPS6 CPNE2 CPNE6 CPSF3L CRMP1 CSAD CTSB DDAH2 DMPK DOCK7 DVL1 DYNC1I1 EEF1A1 EXT2 F13A1 FAF1 FBN3 FGB FLAD1 GAPDH GBP2 GDF9 GNB2 GNB5 HADHB HMGXB3 HOXD8 INPP5K KLHL23 KMT2B LRIF1 MED31 MPPED1 MSH2 NGFR NMT2 NPRL2 OTUB1 PAAF1 PAX8 PDCD6 PDHB PKM PLD3 PRKACA PRKCA PRKCB PRKCG PRKG1 PSMB10 QARS RBBP4 RBM48 RPA1 RPL13 RPS2 S100A10 SDF4 SEMA5B SETDB1 SMPD1 SP110 SRC SRI SUMO3 TAF5L TIAM2 TLE1 TMEM108 TMSB4X TP53 TRMT2A TUBA1A TUBB2B TUBB3 UBE2D1 UCHL5 UNC119 USP4 VIM WDR18 WDR73 ZBTB16 ZNF135 ZNF431
Entrez ID		1287	310
HPRD ID		02363	01720
Ensembl ID		ENSG00000188153	ENSG00000138279
Uniprot IDs		A7MBN3 P29400 Q49AM6	B2R657 P20073
PDB IDs
Enriched GO Terms of Interacting Partners?		Extracellular Matrix Organization Extracellular Structure Organization Anatomical Structure Development System Development Extracellular Matrix Disassembly Developmental Process Regulation Of Growth Response To Abiotic Stimulus Multicellular Organismal Development Nervous System Development Response To Wounding Response To External Stimulus Negative Regulation Of Transport Hemostasis Reproductive Process Endodermal Cell Differentiation Peptide Cross-linking Generation Of Neurons Mating Regulation Of Body Fluid Levels Behavior Neurogenesis Wound Healing Endoderm Formation Positive Regulation Of High-density Lipoprotein Particle Assembly Seminal Vesicle Epithelium Development Positive Regulation Of Secretion Of Lysosomal Enzymes Positive Regulation Of Pancreatic Juice Secretion Fetal Process Involved In Parturition Dendrite Regeneration Tissue Development Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Proteolysis Negative Regulation Of Cell Proliferation Platelet Degranulation Cell Differentiation Response To Stress Regulation Of Neurogenesis Positive Regulation Of Protein Metabolic Process Cell Morphogenesis Involved In Differentiation Skeletal Muscle Cell Proliferation Synaptic Growth At Neuromuscular Junction Mating Plug Formation Regulation Of Cellular Component Organization Regulation Of Cellular Protein Metabolic Process Endoderm Development Regulation Of Cell Growth Negative Regulation Of Proteolysis Negative Regulation Of Protein Processing Negative Regulation Of Ion Transport	Anatomical Structure Development Multicellular Organismal Development Developmental Process System Development Cellular Metabolic Process Metabolic Process Cellular Response To Organic Substance Platelet Activation Regulation Of Protein Metabolic Process Regulation Of Metabolic Process Cellular Response To Growth Factor Stimulus Regulation Of Cellular Protein Metabolic Process Blood Coagulation Response To Growth Factor Programmed Cell Death Hemostasis Negative Regulation Of Cellular Protein Metabolic Process Cell Death Catabolic Process Death Response To Organic Substance Apoptotic Process Histone H3-T6 Phosphorylation Regulation Of Apoptotic Process Nervous System Development Regulation Of Body Fluid Levels Negative Regulation Of Protein Metabolic Process Regulation Of Cell Death Negative Regulation Of Cellular Metabolic Process Regulation Of Protein Catabolic Process Cellular Protein Metabolic Process Regulation Of Proteolysis Mitotic Cell Cycle Process Negative Regulation Of Glucose Transport Organelle Organization Cell Activation Enzyme Linked Receptor Protein Signaling Pathway Regulation Of Catalytic Activity Cellular Process Regulation Of Cellular Response To Insulin Stimulus Wound Healing Cellular Response To Stimulus Regulation Of Proteasomal Protein Catabolic Process Gene Expression Protein Metabolic Process Mitotic Cell Cycle Organ Development Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Chromosome Organization
Tagcloud ?		alport amplified aras ascending audiological audiometric august autosomal certainly curves descending drop eighty exons fibroblast flat groove hearing impairment inheritance moderate oae recessive sensorineural sequenced sixteen wherein xlas	annexin anticancer antitumor chinese cytotoxic cytotoxicity decreasing depressed dramatically eecp ethanol exerted explored huvecs kappa mb mcf mda mitochondrial mu obviously p65 possess propolis ros umbilical upregulating vein
Tagcloud (Difference) ?		alport amplified aras ascending audiological audiometric august autosomal certainly curves descending drop eighty exons fibroblast flat groove hearing impairment inheritance moderate oae recessive sensorineural sequenced sixteen wherein xlas	annexin anticancer antitumor chinese cytotoxic cytotoxicity decreasing depressed dramatically eecp ethanol exerted explored huvecs kappa mb mcf mda mitochondrial mu obviously p65 possess propolis ros umbilical upregulating vein
Tagcloud (Intersection) ?