COL4A5 and HABP2

Number of citations of the paper that reports this interaction (PubMedID 1724753)
0

Data Source:
HPRD (in vivo)

		COL4A5	HABP2
Description		collagen type IV alpha 5 chain	hyaluronan binding protein 2
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Collagen Trimer Collagen Type IV Trimer Basement Membrane Endoplasmic Reticulum Lumen Extracellular Matrix Neuromuscular Junction	Extracellular Region Extracellular Space
	Molecular Function	Extracellular Matrix Structural Constituent Protein Binding Extracellular Matrix Structural Constituent Conferring Tensile Strength	Serine-type Endopeptidase Activity Calcium Ion Binding Glycosaminoglycan Binding Peptidase Activity Serine-type Peptidase Activity Hydrolase Activity
	Biological Process	Neuromuscular Junction Development Collagen-activated Tyrosine Kinase Receptor Signaling Pathway	Proteolysis Cell Adhesion
Pathways		Collagen degradation Collagen degradation Fibronectin matrix formation Collagen biosynthesis and modifying enzymes Signaling by PDGF Assembly of collagen fibrils and other multimeric structures Integrin cell surface interactions Integrin cell surface interactions Anchoring fibril formation Crosslinking of collagen fibrils Laminin interactions Laminin interactions Non-integrin membrane-ECM interactions ECM proteoglycans NCAM1 interactions Collagen chain trimerization Regulation of expression of SLITs and ROBOs Attachment of bacteria to epithelial cells
Drugs			Hyaluronic acid
Diseases		Alport syndrome
GWAS			Breast cancer, ovarian cancer or prostate cancer (pleiotropy) ( 27432226) Cardiac troponin-I levels ( 31014085) Central corneal thickness ( 29760442 32528159) Eosinophil count ( 27863252 32888494) Eosinophil percentage of white cells ( 27863252 32888494) Heel bone mineral density ( 28869591) Ischemic stroke ( 26732560) Peripheral arterial disease (traffic-related air pollution interaction) ( 27082954) Plasma factor VII activating protease levels ( 30070759) Urate levels ( 31578528) Waist-to-hip ratio adjusted for body mass index ( 28430825)
Interacting Genes		46 interacting genes: ABHD4 ANTXR2 ANXA7 APP ATP6V0B BSND CD53 CD79A CD93 CDKN1A CERS4 CLDN7 DAZAP2 DCN ELOVL4 ERGIC3 FAM209A FBLN2 FFAR2 FN1 GPX8 HABP2 KCNJ6 MATN2 MFF MMP9 MTIF3 NCR3LG1 NEMP1 NR1H2 OSM RELL2 RNF10 SAR1A SERPINE2 SLC10A4 SLC10A6 SLC16A2 SLC18A1 SLC35H1 SLC39A2 SMN1 THAP4 TK1 TMEM80 TSPO2	7 interacting genes: COL4A1 COL4A2 COL4A3 COL4A4 COL4A5 COL4A6 KNG1
Entrez ID		1287	3026
HPRD ID		02363	04890
Ensembl ID		ENSG00000188153	ENSG00000148702
Uniprot IDs		A7MBN3 P29400 Q49AM6	Q14520
PDB IDs		5NAZ 6WKU
Enriched GO Terms of Interacting Partners?		Extracellular Matrix Protein Serine/threonine Kinase Binding Glycosaminoglycan Binding Bile Acid:sodium Symporter Activity	Collagen Type IV Trimer Collagen-activated Tyrosine Kinase Receptor Signaling Pathway Extracellular Matrix Structural Constituent Conferring Tensile Strength Collagen-activated Signaling Pathway Collagen Trimer Basement Membrane Endoplasmic Reticulum Lumen Extracellular Matrix Structural Constituent Extracellular Matrix Extracellular Structure Organization Extracellular Matrix Organization Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway Extracellular Region Enzyme-linked Receptor Protein Signaling Pathway Glomerular Basement Membrane Development Neuromuscular Junction Development Cell Surface Receptor Signaling Pathway Cellular Response To Amino Acid Stimulus Response To Amino Acid Signal Transduction Negative Regulation Of Angiogenesis Negative Regulation Of Vasculature Development Retinal Blood Vessel Morphogenesis Molecular Adaptor Activity Synapse Organization Platelet-derived Growth Factor Binding Retina Vasculature Morphogenesis In Camera-type Eye Endothelial Cell Apoptotic Process Negative Regulation Of Vascular Endothelial Cell Proliferation Metalloendopeptidase Inhibitor Activity Angiogenesis Renal Tubule Morphogenesis Regulation Of Angiogenesis Regulation Of Vasculature Development Negative Regulation Of Multicellular Organismal Process
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?