COL4A5 and SLC10A4

Number of citations: 50 (PubMedID 32296183)
Data Source: BioGRID (two hybrid)

		COL4A5	SLC10A4
Name		collagen type IV alpha 5 chain	solute carrier family 10 member 4
Structure			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Collagen Trimer Collagen Type IV Trimer Basement Membrane Endoplasmic Reticulum Lumen Extracellular Matrix Neuromuscular Junction	Plasma Membrane Membrane
	Molecular Function	Extracellular Matrix Structural Constituent Protein Binding Extracellular Matrix Structural Constituent Conferring Tensile Strength	Protein Binding Bile Acid:sodium Symporter Activity Symporter Activity
	Biological Process	Neuromuscular Junction Development Collagen-activated Tyrosine Kinase Receptor Signaling Pathway	Monoatomic Ion Transport Sodium Ion Transport Bile Acid And Bile Salt Transport Transmembrane Transport
Pathways		Collagen degradation Collagen degradation Fibronectin matrix formation Collagen biosynthesis and modifying enzymes Signaling by PDGF Assembly of collagen fibrils and other multimeric structures Integrin cell surface interactions Integrin cell surface interactions Anchoring fibril formation Crosslinking of collagen fibrils Laminin interactions Laminin interactions Non-integrin membrane-ECM interactions ECM proteoglycans NCAM1 interactions Collagen chain trimerization Regulation of expression of SLITs and ROBOs Attachment of bacteria to epithelial cells	None
Diseases		Alport syndrome	None
GWAS		No GWAS studies recorded	Bipolar disorder ( 31043756 ) Crohn's disease ( 23128233 )
Interacting Genes		46 interacting genes: ABHD4 ANTXR2 ANXA7 APP ATP6V0B BSND CD53 CD79A CD93 CDKN1A CERS4 CLDN7 DAZAP2 DCN ELOVL4 ERGIC3 FAM209A FBLN2 FFAR2 FN1 GPX8 HABP2 KCNJ6 MATN2 MFF MMP9 MTIF3 NCR3LG1 NEMP1 NR1H2 OSM RELL2 RNF10 SAR1A SERPINE2 SLC10A4 SLC10A6 SLC16A2 SLC18A1 SLC35H1 SLC39A2 SMN1 THAP4 TK1 TMEM80 TSPO2	5 interacting genes: COL4A5 DNAJC30 SLC35A4 TMEM218 VMA12
Entrez ID		1287	201780
HPRD ID		02363	11562
Ensembl ID		ENSG00000188153	ENSG00000145248
Uniprot IDs		A7MBN3 P29400 Q49AM6	Q96EP9
PDB IDs		5NAZ 6WKU	Not available
GO Terms Enriched among Interactors		Extracellular Matrix Protein Serine/threonine Kinase Binding Glycosaminoglycan Binding Bile Acid:sodium Symporter Activity	Collagen-activated Signaling Pathway Collagen-activated Tyrosine Kinase Receptor Signaling Pathway Collagen Type IV Trimer Regulation Of Mitochondrial ATP Synthesis Coupled Proton Transport Nucleotide-sugar Transmembrane Transport Pyrimidine Nucleotide-sugar Transmembrane Transporter Activity Pyrimidine Nucleotide-sugar Transmembrane Transport COPI-coated Vesicle Membrane Vacuolar Proton-transporting V-type ATPase Complex Assembly Lysosomal Protein Catabolic Process Proton-transporting V-type ATPase Complex Assembly Oxysterol Binding Vacuolar Proton-transporting V-type ATPase Complex Cellular Response To Increased Oxygen Levels Protein Catabolic Process In The Vacuole Regulation Of ATP Biosynthetic Process