COL4A4 and ANTXR2

Number of citations of the paper that reports this interaction (PMID 11683410)
86

Data Source:
HPRD (in vitro)

		COL4A4	ANTXR2
Gene Name		collagen, type IV, alpha 4	anthrax toxin receptor 2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Region Collagen Type IV Trimer Basal Lamina Endoplasmic Reticulum Lumen	Extracellular Region Endoplasmic Reticulum Membrane Plasma Membrane External Side Of Plasma Membrane Endosome Membrane Integral Component Of Membrane
	Molecular Function	Extracellular Matrix Structural Constituent	Receptor Activity Protein Binding Metal Ion Binding
	Biological Process	Axon Guidance Extracellular Matrix Disassembly Extracellular Matrix Organization Collagen Catabolic Process Glomerular Basement Membrane Development	Pathogenesis Reproductive Process Toxin Transport
Pathways		Signaling by PDGF NCAM1 interactions Collagen formation Axon guidance Collagen degradation Anchoring fibril formation Non-integrin membrane-ECM interactions Degradation of the extracellular matrix Assembly of collagen fibrils and other multimeric structures Laminin interactions ECM proteoglycans Integrin cell surface interactions Collagen biosynthesis and modifying enzymes NCAM signaling for neurite out-growth
Drugs
Diseases
GWAS		Immune reponse to smallpox (secreted IFN-alpha) ( 22610502)	Ankylosing spondylitis ( 21743469 20062062)
Protein-Protein Interactions		12 interactors: ANTXR2 CD93 DCN FBLN2 FN1 HABP2 MATN2 MMP9 OSM SAA1 SERPINE2 TGFBI	8 interactors: COL4A2 COL4A3 COL4A4 COL4A5 LAMB1 LAMC1 LRP6 SMAD2
Entrez ID		1286	118429
HPRD ID		00360	07452
Ensembl ID		ENSG00000081052	ENSG00000163297
Uniprot IDs		P53420	J3KPY9 P58335
PDB IDs			1SHT 1SHU 1T6B 1TZN
Enriched GO Terms of Interacting Partners?		Extracellular Matrix Organization Extracellular Structure Organization Extracellular Matrix Disassembly Response To Wounding Wound Healing Endodermal Cell Differentiation Acute-phase Response Leukocyte Migration Regulation Of Cell Adhesion Peptide Cross-linking Endoderm Formation Seminal Vesicle Epithelium Development Dendrite Regeneration Anatomical Structure Morphogenesis Cell Migration Acute Inflammatory Response Cell Motility Endoderm Development Negative Regulation Of Transport Tissue Development Negative Regulation Of Ion Transport Mating Plug Formation Blood Coagulation Hemostasis Response To External Stimulus Tyrosine Phosphorylation Of Stat1 Protein Tyrosine Phosphorylation Of Stat5 Protein System Development Formation Of Primary Germ Layer Oncostatin-M-mediated Signaling Pathway Positive Regulation Of Receptor Binding Calcium-independent Cell-matrix Adhesion Cell Adhesion Positive Regulation Of Keratinocyte Migration Negative Regulation Of Plasminogen Activation Tyrosine Phosphorylation Of Stat3 Protein Regulation Of Body Fluid Levels Locomotion Immune System Process Chemotaxis Regulation Of Growth Reproductive Process Nervous System Development Multicellular Organismal Development Response To Stress Gastrulation Platelet Activation Cell Activation Negative Regulation Of Platelet Aggregation Tyrosine Phosphorylation Of STAT Protein	Extracellular Matrix Disassembly Cell Morphogenesis Involved In Differentiation Extracellular Matrix Organization Extracellular Structure Organization Axon Guidance Cell Development Cell Morphogenesis Axonogenesis Collagen Catabolic Process Neuron Differentiation Axon Development Cell Morphogenesis Involved In Neuron Differentiation Chemotaxis Collagen Metabolic Process Locomotion Endoderm Development Multicellular Organismal Macromolecule Metabolic Process Neuron Projection Morphogenesis Multicellular Organismal Metabolic Process Anatomical Structure Morphogenesis Movement Of Cell Or Subcellular Component Generation Of Neurons Neuron Projection Development Cell Projection Morphogenesis Cell Part Morphogenesis Neurogenesis Neuron Development Response To External Stimulus Cell Differentiation Gastrulation Cell Projection Organization Endoderm Formation Nervous System Development System Development Multicellular Organismal Development Anatomical Structure Development Formation Of Primary Germ Layer Developmental Process Glomerular Basement Membrane Development Response To Cholesterol Dorsal/ventral Axis Specification Pericardium Development Embryonic Morphogenesis Regulation Of Cell Proliferation Endodermal Cell Differentiation Tissue Development Substrate Adhesion-dependent Cell Spreading Regulation Of Epithelial Cell Proliferation Kidney Development Renal System Development
Tagcloud ?		alport basement clarification classic diagnostics families focal fsgs gbm glomerulosclerosis hematuria hereditary heterozygous histologic illustrates inconsistent inherited interpretation nephritis nephropathy nephrotic pathognomonic predominant proteinuria segmental segregated thin variants
Tagcloud (Difference) ?		alport basement clarification classic diagnostics families focal fsgs gbm glomerulosclerosis hematuria hereditary heterozygous histologic illustrates inconsistent inherited interpretation nephritis nephropathy nephrotic pathognomonic predominant proteinuria segmental segregated thin variants
Tagcloud (Intersection) ?