ANTXR2 and COL4A2

Number of citations of the paper that reports this interaction (PMID 11683410)
86

Data Source:
HPRD (in vivo)

		ANTXR2	COL4A2
Gene Name		anthrax toxin receptor 2	collagen, type IV, alpha 2
Image
Gene Ontology Annotations	Cellular Component	Extracellular Region Endoplasmic Reticulum Membrane Plasma Membrane External Side Of Plasma Membrane Endosome Membrane Integral Component Of Membrane	Extracellular Region Collagen Type IV Trimer Endoplasmic Reticulum Lumen Extracellular Matrix Intracellular Membrane-bounded Organelle Extracellular Vesicular Exosome
	Molecular Function	Receptor Activity Protein Binding Metal Ion Binding	Extracellular Matrix Structural Constituent Protein Binding
	Biological Process	Pathogenesis Reproductive Process Toxin Transport	Angiogenesis Transcription, DNA-templated Receptor-mediated Endocytosis Axon Guidance Negative Regulation Of Angiogenesis Extracellular Matrix Disassembly Extracellular Matrix Organization Collagen Catabolic Process Endodermal Cell Differentiation Cellular Response To Transforming Growth Factor Beta Stimulus
Pathways			Signaling by PDGF NCAM1 interactions Collagen formation Axon guidance Collagen degradation Anchoring fibril formation Non-integrin membrane-ECM interactions Degradation of the extracellular matrix Assembly of collagen fibrils and other multimeric structures Laminin interactions ECM proteoglycans Integrin cell surface interactions Collagen biosynthesis and modifying enzymes NCAM signaling for neurite out-growth Scavenging by Class A Receptors
Drugs
Diseases
GWAS		Ankylosing spondylitis ( 21743469 20062062)	Coronary artery calcification ( 22144573) Coronary heart disease ( 21378990)
Protein-Protein Interactions		8 interactors: COL4A2 COL4A3 COL4A4 COL4A5 LAMB1 LAMC1 LRP6 SMAD2	23 interactors: ANTXR2 ANXA7 APP ATF7IP BGN BMP3 CD93 COL4A1 CSNK2B DAZAP2 FAM46A FBLN2 FN1 HABP2 MATN2 MMP9 OSM SAA1 SERPINE2 SKIL SMN1 TGFBI TK1
Entrez ID		118429	1284
HPRD ID		07452	00355
Ensembl ID		ENSG00000163297	ENSG00000134871
Uniprot IDs		J3KPY9 P58335	P08572
PDB IDs		1SHT 1SHU 1T6B 1TZN	1LI1
Enriched GO Terms of Interacting Partners?		Extracellular Matrix Disassembly Cell Morphogenesis Involved In Differentiation Extracellular Matrix Organization Extracellular Structure Organization Axon Guidance Cell Development Cell Morphogenesis Axonogenesis Collagen Catabolic Process Neuron Differentiation Axon Development Cell Morphogenesis Involved In Neuron Differentiation Chemotaxis Collagen Metabolic Process Locomotion Endoderm Development Multicellular Organismal Macromolecule Metabolic Process Neuron Projection Morphogenesis Multicellular Organismal Metabolic Process Anatomical Structure Morphogenesis Movement Of Cell Or Subcellular Component Generation Of Neurons Neuron Projection Development Cell Projection Morphogenesis Cell Part Morphogenesis Neurogenesis Neuron Development Response To External Stimulus Cell Differentiation Gastrulation Cell Projection Organization Endoderm Formation Nervous System Development System Development Multicellular Organismal Development Anatomical Structure Development Formation Of Primary Germ Layer Developmental Process Glomerular Basement Membrane Development Response To Cholesterol Dorsal/ventral Axis Specification Pericardium Development Embryonic Morphogenesis Regulation Of Cell Proliferation Endodermal Cell Differentiation Tissue Development Substrate Adhesion-dependent Cell Spreading Regulation Of Epithelial Cell Proliferation Kidney Development Renal System Development	Extracellular Matrix Organization Extracellular Structure Organization Tissue Development Chemotaxis Anatomical Structure Development System Development Nervous System Development Axon Guidance Cell Morphogenesis Involved In Differentiation Hemostasis Generation Of Neurons Developmental Process Multicellular Organismal Development Neurogenesis Cell Differentiation Locomotion Extracellular Matrix Disassembly Axonogenesis Response To External Stimulus Axon Development Regulation Of Body Fluid Levels Anatomical Structure Morphogenesis Cell Morphogenesis Involved In Neuron Differentiation Neuron Projection Morphogenesis Movement Of Cell Or Subcellular Component Cell Morphogenesis Response To Wounding Blood Coagulation Endodermal Cell Differentiation Acute-phase Response Platelet Activation Neuron Projection Development Positive Regulation Of Pathway-restricted SMAD Protein Phosphorylation Cell Projection Morphogenesis Cell Development Peptide Cross-linking Reproductive Process Cell Part Morphogenesis Seminal Vesicle Epithelium Development Fetal Process Involved In Parturition Dendrite Regeneration Mating Neuromuscular Junction Development Leukocyte Migration Regulation Of Pathway-restricted SMAD Protein Phosphorylation Endoderm Formation Neuron Development Collagen Catabolic Process Regulation Of Binding Behavior
Tagcloud ?			13q33 bptf d13s1315 d13s158 d13s278 d13s285 d13s779 d13s796 e2f ets flanking genomatix heterozygosity hif1 ing ing1 loh matinspector microdeletion nrsf rel softwares sox sox1 tfsearch tsg tsgs warrants
Tagcloud (Difference) ?			13q33 bptf d13s1315 d13s158 d13s278 d13s285 d13s779 d13s796 e2f ets flanking genomatix heterozygosity hif1 ing ing1 loh matinspector microdeletion nrsf rel softwares sox sox1 tfsearch tsg tsgs warrants
Tagcloud (Intersection) ?