ANTXR2 and COL4A3

Number of citations of the paper that reports this interaction (PMID 11683410)
86

Data Source:
HPRD (in vivo)

		ANTXR2	COL4A3
Gene Name		anthrax toxin receptor 2	collagen, type IV, alpha 3 (Goodpasture antigen)
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Region Endoplasmic Reticulum Membrane Plasma Membrane External Side Of Plasma Membrane Endosome Membrane Integral Component Of Membrane	Extracellular Region Collagen Type IV Trimer Basement Membrane Endoplasmic Reticulum Lumen
	Molecular Function	Receptor Activity Protein Binding Metal Ion Binding	Integrin Binding Structural Molecule Activity Extracellular Matrix Structural Constituent Protein Binding Metalloendopeptidase Inhibitor Activity
	Biological Process	Pathogenesis Reproductive Process Toxin Transport	Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Cell Adhesion Cell Surface Receptor Signaling Pathway Axon Guidance Sensory Perception Of Sound Blood Circulation Cell Proliferation Negative Regulation Of Cell Proliferation Negative Regulation Of Endopeptidase Activity Negative Regulation Of Angiogenesis Extracellular Matrix Disassembly Extracellular Matrix Organization Collagen Catabolic Process Glomerular Basement Membrane Development Endothelial Cell Apoptotic Process
Pathways			Signaling by PDGF NCAM1 interactions Collagen formation Axon guidance Collagen degradation Anchoring fibril formation Non-integrin membrane-ECM interactions Degradation of the extracellular matrix Assembly of collagen fibrils and other multimeric structures Laminin interactions ECM proteoglycans Integrin cell surface interactions Collagen biosynthesis and modifying enzymes NCAM signaling for neurite out-growth
Drugs
Diseases
GWAS		Ankylosing spondylitis ( 21743469 20062062)	Corneal structure ( 23291589) Metabolite levels (5-HIAA/ MHPG Ratio) ( 23319000)
Protein-Protein Interactions		8 interactors: COL4A2 COL4A3 COL4A4 COL4A5 LAMB1 LAMC1 LRP6 SMAD2	17 interactors: ANTXR2 APP CAMK2B CD93 COL4A3BP DCN FBLN2 FN1 HABP2 MATN2 MFAP2 MMP9 OSM SAA1 SERPINE2 TGFBI USH2A
Entrez ID		118429	1285
HPRD ID		07452	00354
Ensembl ID		ENSG00000163297	ENSG00000169031
Uniprot IDs		J3KPY9 P58335	Q01955
PDB IDs		1SHT 1SHU 1T6B 1TZN
Enriched GO Terms of Interacting Partners?		Extracellular Matrix Disassembly Cell Morphogenesis Involved In Differentiation Extracellular Matrix Organization Extracellular Structure Organization Axon Guidance Cell Development Cell Morphogenesis Axonogenesis Collagen Catabolic Process Neuron Differentiation Axon Development Cell Morphogenesis Involved In Neuron Differentiation Chemotaxis Collagen Metabolic Process Locomotion Endoderm Development Multicellular Organismal Macromolecule Metabolic Process Neuron Projection Morphogenesis Multicellular Organismal Metabolic Process Anatomical Structure Morphogenesis Movement Of Cell Or Subcellular Component Generation Of Neurons Neuron Projection Development Cell Projection Morphogenesis Cell Part Morphogenesis Neurogenesis Neuron Development Response To External Stimulus Cell Differentiation Gastrulation Cell Projection Organization Endoderm Formation Nervous System Development System Development Multicellular Organismal Development Anatomical Structure Development Formation Of Primary Germ Layer Developmental Process Glomerular Basement Membrane Development Response To Cholesterol Dorsal/ventral Axis Specification Pericardium Development Embryonic Morphogenesis Regulation Of Cell Proliferation Endodermal Cell Differentiation Tissue Development Substrate Adhesion-dependent Cell Spreading Regulation Of Epithelial Cell Proliferation Kidney Development Renal System Development	Extracellular Matrix Organization Extracellular Structure Organization System Development Immune System Process Response To Wounding Multicellular Organismal Development Anatomical Structure Development Anatomical Structure Morphogenesis Extracellular Matrix Disassembly Developmental Process Wound Healing Generation Of Neurons Cell Morphogenesis Nervous System Development Neurogenesis Cell Activation Cell Morphogenesis Involved In Differentiation Blood Coagulation Cell Differentiation Reproductive Process Hemostasis Response To Stress Platelet Activation Endodermal Cell Differentiation Acute-phase Response Regulation Of Meiosis Peptide Cross-linking Organ Development Leukocyte Migration Mating Regulation Of Body Fluid Levels Regulation Of Meiotic Cell Cycle Chemotaxis Endoderm Formation Response To Abiotic Stimulus Regulation Of Growth Seminal Vesicle Epithelium Development Dendrite Regeneration Inhibitory G-protein Coupled Receptor Phosphorylation Regulation Of Cell Adhesion Tissue Development Neurological System Process Response To External Stimulus Cell Adhesion Platelet Degranulation Regulation Of Neurogenesis Acute Inflammatory Response Locomotion Neuromuscular Process Controlling Balance Synaptic Growth At Neuromuscular Junction
Tagcloud ?			alport amplified aras ascending audiological audiometric august autosomal certainly curves descending drop eighty exons fibroblast flat groove hearing impairment inheritance moderate oae recessive sensorineural sequenced sixteen wherein xlas
Tagcloud (Difference) ?			alport amplified aras ascending audiological audiometric august autosomal certainly curves descending drop eighty exons fibroblast flat groove hearing impairment inheritance moderate oae recessive sensorineural sequenced sixteen wherein xlas
Tagcloud (Intersection) ?