ANTXR2 and LAMC1

Number of citations of the paper that reports this interaction (PubMedID 11683410)
0

Data Source:
BioGRID (pull down)

		ANTXR2	LAMC1
Description		ANTXR cell adhesion molecule 2	laminin subunit gamma 1
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GO Annotations	Cellular Component	Extracellular Region Endoplasmic Reticulum Endoplasmic Reticulum Membrane Plasma Membrane External Side Of Plasma Membrane Cell Surface Endosome Membrane Membrane	Extracellular Region Basement Membrane Laminin-1 Complex Extracellular Space Endoplasmic Reticulum Lumen Extracellular Matrix Laminin-10 Complex Laminin-11 Complex Extracellular Exosome Protein Complex Involved In Cell-matrix Adhesion
	Molecular Function	Transmembrane Signaling Receptor Activity Protein Binding Signaling Receptor Activity Metal Ion Binding	Extracellular Matrix Structural Constituent Extracellular Matrix Constituent Conferring Elasticity
	Biological Process	Single Fertilization Collagen Fibril Organization Uterus Development	Cell Adhesion Endoderm Development Tissue Development Cell Migration Extracellular Matrix Disassembly Hemidesmosome Assembly Substrate Adhesion-dependent Cell Spreading Maintenance Of Blood-brain Barrier Positive Regulation Of Cell Adhesion Positive Regulation Of Epithelial Cell Proliferation Positive Regulation Of Muscle Cell Differentiation Protein-containing Complex Assembly Regulation Of Basement Membrane Organization Positive Regulation Of Integrin-mediated Signaling Pathway
Pathways			Degradation of the extracellular matrix Laminin interactions Laminin interactions Non-integrin membrane-ECM interactions ECM proteoglycans L1CAM interactions Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) MET activates PTK2 signaling Post-translational protein phosphorylation EGR2 and SOX10-mediated initiation of Schwann cell myelination Attachment of bacteria to epithelial cells Formation of the dystrophin-glycoprotein complex (DGC) Formation of the dystrophin-glycoprotein complex (DGC) Developmental Lineage of Pancreatic Ductal Cells
Drugs		MDX-1303	Lanoteplase
Diseases		Infantile systemic hyalinosis and juvenile hyaline fibromatosis
GWAS		Adult body size ( 32376654) Ankylosing spondylitis ( 21743469 20062062) Bipolar disorder (inflammation and infection response interaction) ( 25781172) Carotid plaque burden ( 28282560) Childhood ALL/LBL (acute lymphoblastic leukemia/lymphoblastic lymphoma) treatment-related venous thromboembolism ( 32438682) Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) ( 26974007) Essential hypertension (time to event) ( 32589924) Hand grip strength ( 29691431) Lymphocyte count ( 27863252 32888494) Lymphocyte percentage of white cells ( 27863252 32888494) Myopia ( 27182965) Neutrophil percentage of white cells ( 27863252 32888494) Refractive error ( 32231278) Response to cognitive-behavioural therapy in major depressive disorder ( 31123309) Spherical equivalent or myopia (age of diagnosis) ( 29808027) White blood cell count ( 32888494)	Apolipoprotein A1 levels ( 32203549) Appendicular lean mass ( 33097823) Clozapine-induced agranulocytosis ( 25187353) Colorectal cancer ( 23266556) Colorectal cancer or advanced adenoma ( 30510241) Diastolic blood pressure ( 30224653) Fuchs's corneal dystrophy ( 28358029) HDL cholesterol levels ( 32203549) Height ( 31562340) Hemoglobin ( 32888494) Hypertriglyceridemia ( 27599772) LDL cholesterol levels in HIV infection ( 33109212) Red blood cell count ( 32888494) Systemic lupus erythematosus ( 24871463)
Interacting Genes		9 interacting genes: CFTR COL4A2 COL4A3 COL4A4 COL4A5 LAMB1 LAMC1 LRP6 SMAD2	17 interacting genes: ANTXR2 APP ATF7IP CENPU FILNC1 KEAP1 LAMA5 NID1 NID2 SMARCA2 SNAPIN SNX2 SRPK1 TANK UBC WASHC3 WEE2-AS1
Entrez ID		118429	3915
HPRD ID		07452	01030
Ensembl ID		ENSG00000163297	ENSG00000135862
Uniprot IDs		A4FUA5 J3KPY9 P58335 Q32Q26	P11047 Q6NVY8
PDB IDs		1SHT 1SHU 1T6B 1TZN 7N1O 8FT6 8FT8 8FZ4 8FZU 8FZV 9DOC	5XAU 7CEC 8DMK
Enriched GO Terms of Interacting Partners?		Basement Membrane Extracellular Matrix Structural Constituent Collagen Type IV Trimer Extracellular Matrix Extracellular Matrix Structural Constituent Conferring Tensile Strength Endoplasmic Reticulum Lumen Collagen-activated Tyrosine Kinase Receptor Signaling Pathway Collagen-activated Signaling Pathway Collagen Trimer Laminin-1 Complex Laminin-10 Complex Regulation Of Basement Membrane Organization Protein Complex Involved In Cell-matrix Adhesion Extracellular Structure Organization Extracellular Matrix Organization Glomerular Basement Membrane Development Positive Regulation Of Integrin-mediated Signaling Pathway Regulation Of Integrin-mediated Signaling Pathway Response To Cholesterol Developmental Process Extracellular Region Endoderm Development Endodermal Cell Differentiation Animal Organ Morphogenesis Substrate Adhesion-dependent Cell Spreading Intracellularly ATP-gated Chloride Channel Activity Positive Regulation Of Voltage-gated Chloride Channel Activity Sec61 Translocon Complex Binding Response To Alcohol Laminin-8 Complex Neuronal-glial Interaction Involved In Cerebral Cortex Radial Glia Guided Migration CAAX-box Protein Maturation Enzyme-linked Receptor Protein Signaling Pathway Regulation Of Extracellular Matrix Organization Response To Transforming Growth Factor Beta Positive Regulation Of Anion Channel Activity Laminin-2 Complex Positive Regulation Of Muscle Cell Differentiation Roof Of Mouth Development Homomeric SMAD Protein Complex Regulation Of ERK5 Cascade Angiotensin-activated Signaling Pathway Involved In Heart Process Odontogenesis Anatomical Structure Formation Involved In Morphogenesis Positive Regulation Of Monoatomic Anion Transport Regulation Of Epithelial Cell Proliferation Laminin-11 Complex Zygotic Specification Of Dorsal/ventral Axis Activin Responsive Factor Complex Paraxial Mesoderm Morphogenesis	Extracellular Matrix Organization Extracellular Structure Organization Basement Membrane Extracellular Matrix Structural Constituent Insulin Receptor Binding
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