ANTXR2 and COL4A4

Number of citations of the paper that reports this interaction (PMID 11683410)
86

Data Source:
HPRD (in vitro)

		ANTXR2	COL4A4
Gene Name		anthrax toxin receptor 2	collagen, type IV, alpha 4
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Region Endoplasmic Reticulum Membrane Plasma Membrane External Side Of Plasma Membrane Endosome Membrane Integral Component Of Membrane	Extracellular Region Collagen Type IV Trimer Basal Lamina Endoplasmic Reticulum Lumen
	Molecular Function	Receptor Activity Protein Binding Metal Ion Binding	Extracellular Matrix Structural Constituent
	Biological Process	Pathogenesis Reproductive Process Toxin Transport	Axon Guidance Extracellular Matrix Disassembly Extracellular Matrix Organization Collagen Catabolic Process Glomerular Basement Membrane Development
Pathways			Signaling by PDGF NCAM1 interactions Collagen formation Axon guidance Collagen degradation Anchoring fibril formation Non-integrin membrane-ECM interactions Degradation of the extracellular matrix Assembly of collagen fibrils and other multimeric structures Laminin interactions ECM proteoglycans Integrin cell surface interactions Collagen biosynthesis and modifying enzymes NCAM signaling for neurite out-growth
Drugs
Diseases
GWAS		Ankylosing spondylitis ( 21743469 20062062)	Immune reponse to smallpox (secreted IFN-alpha) ( 22610502)
Protein-Protein Interactions		8 interactors: COL4A2 COL4A3 COL4A4 COL4A5 LAMB1 LAMC1 LRP6 SMAD2	12 interactors: ANTXR2 CD93 DCN FBLN2 FN1 HABP2 MATN2 MMP9 OSM SAA1 SERPINE2 TGFBI
Entrez ID		118429	1286
HPRD ID		07452	00360
Ensembl ID		ENSG00000163297	ENSG00000081052
Uniprot IDs		J3KPY9 P58335	P53420
PDB IDs		1SHT 1SHU 1T6B 1TZN
Enriched GO Terms of Interacting Partners?		Extracellular Matrix Disassembly Cell Morphogenesis Involved In Differentiation Extracellular Matrix Organization Extracellular Structure Organization Axon Guidance Cell Development Cell Morphogenesis Axonogenesis Collagen Catabolic Process Neuron Differentiation Axon Development Cell Morphogenesis Involved In Neuron Differentiation Chemotaxis Collagen Metabolic Process Locomotion Endoderm Development Multicellular Organismal Macromolecule Metabolic Process Neuron Projection Morphogenesis Multicellular Organismal Metabolic Process Anatomical Structure Morphogenesis Movement Of Cell Or Subcellular Component Generation Of Neurons Neuron Projection Development Cell Projection Morphogenesis Cell Part Morphogenesis Neurogenesis Neuron Development Response To External Stimulus Cell Differentiation Gastrulation Cell Projection Organization Endoderm Formation Nervous System Development System Development Multicellular Organismal Development Anatomical Structure Development Formation Of Primary Germ Layer Developmental Process Glomerular Basement Membrane Development Response To Cholesterol Dorsal/ventral Axis Specification Pericardium Development Embryonic Morphogenesis Regulation Of Cell Proliferation Endodermal Cell Differentiation Tissue Development Substrate Adhesion-dependent Cell Spreading Regulation Of Epithelial Cell Proliferation Kidney Development Renal System Development	Extracellular Matrix Organization Extracellular Structure Organization Extracellular Matrix Disassembly Response To Wounding Wound Healing Endodermal Cell Differentiation Acute-phase Response Leukocyte Migration Regulation Of Cell Adhesion Peptide Cross-linking Endoderm Formation Seminal Vesicle Epithelium Development Dendrite Regeneration Anatomical Structure Morphogenesis Cell Migration Acute Inflammatory Response Cell Motility Endoderm Development Negative Regulation Of Transport Tissue Development Negative Regulation Of Ion Transport Mating Plug Formation Blood Coagulation Hemostasis Response To External Stimulus Tyrosine Phosphorylation Of Stat1 Protein Tyrosine Phosphorylation Of Stat5 Protein System Development Formation Of Primary Germ Layer Oncostatin-M-mediated Signaling Pathway Positive Regulation Of Receptor Binding Calcium-independent Cell-matrix Adhesion Cell Adhesion Positive Regulation Of Keratinocyte Migration Negative Regulation Of Plasminogen Activation Tyrosine Phosphorylation Of Stat3 Protein Regulation Of Body Fluid Levels Locomotion Immune System Process Chemotaxis Regulation Of Growth Reproductive Process Nervous System Development Multicellular Organismal Development Response To Stress Gastrulation Platelet Activation Cell Activation Negative Regulation Of Platelet Aggregation Tyrosine Phosphorylation Of STAT Protein
Tagcloud ?			alport basement clarification classic diagnostics families focal fsgs gbm glomerulosclerosis hematuria hereditary heterozygous histologic illustrates inconsistent inherited interpretation nephritis nephropathy nephrotic pathognomonic predominant proteinuria segmental segregated thin variants
Tagcloud (Difference) ?			alport basement clarification classic diagnostics families focal fsgs gbm glomerulosclerosis hematuria hereditary heterozygous histologic illustrates inconsistent inherited interpretation nephritis nephropathy nephrotic pathognomonic predominant proteinuria segmental segregated thin variants
Tagcloud (Intersection) ?