COL9A3

Description		collagen type IX alpha 3 chain
Image
GO Annotations	Cellular Component	Extracellular Region Collagen Trimer Collagen Type IX Trimer Basement Membrane Endoplasmic Reticulum Lumen Extracellular Matrix
	Molecular Function	Extracellular Matrix Structural Constituent Conferring Tensile Strength Protein Homodimerization Activity
	Biological Process
Pathways		Collagen degradation Collagen biosynthesis and modifying enzymes Signaling by PDGF Assembly of collagen fibrils and other multimeric structures Integrin cell surface interactions ECM proteoglycans NCAM1 interactions Collagen chain trimerization
Drugs
Diseases		Multiple epiphyseal dysplasia (MED)
GWAS
Interacting Genes		4 interacting genes: COL2A1 EGFR ERBB2 MAG
Entrez ID		1299
HPRD ID		00374
Ensembl ID		ENSG00000092758
Uniprot IDs		Q14050
PDB IDs		5CTD 5CTI 5CVA 5CVB
Enriched GO Terms of Interacting Partners?		ERBB2-EGFR Signaling Pathway Negative Regulation Of Programmed Cell Death Negative Regulation Of Apoptotic Process ERBB2 Signaling Pathway Cellular Response To Growth Factor Stimulus Myelin Sheath Response To Growth Factor Regulation Of Programmed Cell Death Regulation Of Apoptotic Process Regulation Of Cell Growth Cellular Response To Epidermal Growth Factor Stimulus Transmembrane Receptor Protein Tyrosine Kinase Activity Response To Epidermal Growth Factor Epidermal Growth Factor Receptor Signaling Pathway Basal Plasma Membrane ERBB Signaling Pathway Ruffle Membrane Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Regulation Of Growth Myelination Axon Ensheathment Negative Regulation Of Cell Differentiation Multivesicular Body, Internal Vesicle Lumen Ossification Protein Tyrosine Kinase Activity Embryonic Organ Development Nervous System Process Positive Regulation Of Cell Growth Shc-EGFR Complex ERBB3:ERBB2 Complex Mesaxon Collagen Type II Trimer Negative Regulation Of Developmental Process Positive Regulation Of Protein Kinase C Signaling Epidermal Growth Factor Receptor Activity RNA Polymerase I Core Binding Ganglioside GT1b Binding Receptor Complex System Development Positive Regulation Of Epithelial Cell Proliferation Response To Wounding Membrane Raft Epidermal Growth Factor Binding Compact Myelin Collagen Type XI Trimer Anterior Head Development Regulation Of Protein Kinase C Signaling Transmembrane Signaling Receptor Activity Positive Regulation Of Protein Phosphorylation Basolateral Plasma Membrane
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