ADH5 and PQLC1

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		ADH5	PQLC1
Gene Name		alcohol dehydrogenase 5 (class III), chi polypeptide	PQ loop repeat containing 1
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Mitochondrion Extracellular Vesicular Exosome	Integral Component Of Membrane
	Molecular Function	Alcohol Dehydrogenase (NAD) Activity Fatty Acid Binding Zinc Ion Binding Electron Carrier Activity Formaldehyde Dehydrogenase Activity Protein Homodimerization Activity S-(hydroxymethyl)glutathione Dehydrogenase Activity
	Biological Process	Retinoid Metabolic Process Respiratory System Process Ethanol Catabolic Process Ethanol Oxidation Aging Peptidyl-cysteine S-nitrosylation Response To Lipopolysaccharide Positive Regulation Of Blood Pressure Formaldehyde Catabolic Process Response To Nitrosative Stress Response To Redox State
Pathways
Drugs		NADH Nicotinamide-Adenine-Dinucleotide 12-Hydroxydodecanoic Acid S-Hydroxymethyl Glutathione
Diseases
GWAS		Alcohol dependence ( 23456092) Obesity-related traits ( 23251661)
Protein-Protein Interactions		9 interactors: APP ARNT CHD3 CSNK2B ESRRA PQLC1 PRDX1 SNTA1 VTN	1 interactors: ADH5
Entrez ID		128	80148
HPRD ID		00064	11454
Ensembl ID		ENSG00000197894	ENSG00000122490
Uniprot IDs		P11766 Q6IRT1	G5E989 Q8N2U9
PDB IDs		1M6H 1M6W 1MA0 1MC5 1MP0 1TEH 2FZE 2FZW 3QJ5
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway Intracellular Receptor Signaling Pathway Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway Regulation Of Binding Regulation Of Metabolic Process Neuromuscular Junction Development Regulation Of Cellular Protein Metabolic Process Regulation Of Cellular Amino Acid Metabolic Process Regulation Of Protein Metabolic Process Response To Oxidative Stress Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Vasoconstriction By Circulating Norepinephrine Positive Regulation Of Protein Metabolic Process Regulation Of Cellular Ketone Metabolic Process Regulation Of Phosphorylation Positive Regulation Of Cellular Metabolic Process Synaptic Growth At Neuromuscular Junction Regulation Of Phosphorus Metabolic Process Regulation Of Signal Transduction Hormone-mediated Signaling Pathway Collateral Sprouting In Absence Of Injury Regulation Of Protein Binding Multicellular Organismal Development Regulation Of Cellular Component Movement Synapse Organization Anatomical Structure Development Regulation Of Myeloid Cell Differentiation Regulation Of Signaling Regulation Of Nitrogen Compound Metabolic Process Collateral Sprouting Axon Midline Choice Point Recognition Negative Regulation Of Peptidyl-cysteine S-nitrosylation Regulation Of Cellular Response To Growth Factor Stimulus Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Regulation Of Transcription From RNA Polymerase II Promoter Innate Immune Response Cellular Response To Oxidative Stress Negative Regulation Of Cellular Protein Metabolic Process Regulation Of Peptidyl-tyrosine Phosphorylation Axon Choice Point Recognition Positive Regulation Of Metabolic Process Positive Regulation Of Activin Receptor Signaling Pathway Negative Regulation Of Protein Metabolic Process Positive Regulation Of Protein Modification Process Developmental Process Adiponectin-activated Signaling Pathway Neuron Remodeling Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Endopeptidase Activity Negative Regulation Of Peptidase Activity	Peptidyl-cysteine S-nitrosylation Response To Nitrosative Stress Formaldehyde Catabolic Process Ethanol Catabolic Process Response To Redox State Respiratory System Process Aldehyde Catabolic Process Ethanol Oxidation Positive Regulation Of Blood Pressure Alcohol Catabolic Process Respiratory Gaseous Exchange Cellular Aldehyde Metabolic Process Retinoid Metabolic Process Diterpenoid Metabolic Process Isoprenoid Metabolic Process Regulation Of Blood Pressure Blood Circulation Response To Lipopolysaccharide Aging Response To Molecule Of Bacterial Origin Alcohol Metabolic Process Response To Bacterium
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