SLC66A2 and STX12

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		SLC66A2	STX12
Description		solute carrier family 66 member 2	syntaxin 12
Image		No pdb structure
GO Annotations	Cellular Component	Endosome Trans-Golgi Network Cytosol Membrane	Golgi Membrane Phagophore Assembly Site Nucleoplasm Endosome Golgi Apparatus Synaptic Vesicle Endosome Membrane Endomembrane System Membrane Synaptic Vesicle Membrane BLOC-1 Complex SNARE Complex Cytoplasmic Vesicle Early Endosome Membrane Vesicle Membrane Raft Phagocytic Vesicle Recycling Endosome Recycling Endosome Membrane Postsynaptic Recycling Endosome
	Molecular Function	Protein Binding	SNARE Binding SNAP Receptor Activity Protein Binding
	Biological Process	Retrograde Transport, Endosome To Golgi Phospholipid Translocation	Autophagosome Assembly Intracellular Protein Transport Vesicle Fusion Protein Transport Vesicle-mediated Transport Endocytic Recycling Cholesterol Efflux Vesicle Docking Protein Stabilization Regulation Of Biological Quality
Pathways
Drugs
Diseases
GWAS
Interacting Genes		24 interacting genes: ADH5 AQP6 BEST2 CD79A CLCN7 DIABLO FBLN1 FUNDC2 GJA8 GPR152 IL10RA KCNK5 MGLL RHBDD1 SLC10A1 SLC10A6 SLC25A46 SLC35E3 SLC71A2 STX12 TMEM31 TMEM44 TMEM80 ZFYVE27	44 interacting genes: AQP6 AQP8 BCL2L13 BLOC1S6 CD79A CISD2 DNAJC5 DTX2 EBP EEA1 EPB42 ERGIC3 FAM209A FCER1G GORAB HOMER1 KASH5 LEPROTL1 LMNA MFSD6 MMGT1 NAPA NEMP1 NSG1 PDZK1IP1 PLPPR2 RIC3 SEC11C SLC10A1 SLC10A6 SLC66A2 SNAP23 SNAP25 SNAP29 STX1A STX2 STXBP5L TIMMDC1 TLCD4 TMEM14B TMEM167B TMEM31 TMEM86B TMX2
Entrez ID		80148	23673
HPRD ID		11454	06059
Ensembl ID		ENSG00000122490	ENSG00000117758
Uniprot IDs		K7ERV4 Q8N2U9	Q86Y82
PDB IDs			2DNX
Enriched GO Terms of Interacting Partners?		Transmembrane Transport Membrane Bile Acid:sodium Symporter Activity Chloride Transmembrane Transport Chloride Transport Bile Acid And Bile Salt Transport Inorganic Anion Transmembrane Transport S-(hydroxymethyl)glutathione Dehydrogenase (NADP+) Activity Formaldehyde Dehydrogenase (NAD+) Activity S-(hydroxymethyl)glutathione Dehydrogenase (NAD+) Activity Nitrate Transmembrane Transporter Activity Monoatomic Anion Transmembrane Transport Inorganic Anion Transport Channel Activity Monoatomic Anion Transport Monoatomic Ion Transport Interleukin-10 Binding Organic Hydroxy Compound Transport Intracellularly Ligand-gated Monoatomic Ion Channel Activity Nucleotide-sugar Transmembrane Transporter Activity Sodium-dependent Organic Anion Transmembrane Transporter Activity Sodium-dependent Organic Anion Transport	Membrane SNARE Complex Exocytosis Membrane Fusion Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane Vesicle Fusion To Plasma Membrane SNAP Receptor Activity Membrane Organization Secretion By Cell Synaptic Vesicle Membrane Organization Synaptic Vesicle Priming Vesicle-mediated Transport Vesicle Fusion Syntaxin Binding Organelle Membrane Fusion Secretion Organelle Fusion Organelle Localization By Membrane Tethering Membrane Docking Synaptic Vesicle Docking Vesicle Organization Vesicle Docking Establishment Of Localization In Cell Organelle Localization SNARE Binding Protein Binding Synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I Complex Synaptobrevin 2-SNAP-25-syntaxin-1a Complex Presynaptic Active Zone Membrane Signal Release Bile Acid:sodium Symporter Activity Cellular Localization Synaptic Vesicle Exocytosis Vesicle-mediated Transport In Synapse Mitochondrial Membrane ATP-dependent Protein Binding Regulated Exocytosis Vesicle Docking Involved In Exocytosis Ammonium Channel Activity Cytoplasmic Vesicle Ammonium Transmembrane Transport Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I Presynapse Regulation Of Synaptic Vesicle Priming Water Channel Activity Tertiary Granule Membrane Intracellular Transport BLOC-1 Complex Vesicle Targeting Somatodendritic Compartment
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