SLC66A2 and SLC25A46

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		SLC66A2	SLC25A46
Description		solute carrier family 66 member 2	solute carrier family 25 member 46
Image		No pdb structure
GO Annotations	Cellular Component	Endosome Trans-Golgi Network Cytosol Membrane	Mitochondrion Mitochondrial Outer Membrane Membrane
	Molecular Function	Protein Binding	Protein Binding Protein-containing Complex Binding
	Biological Process	Retrograde Transport, Endosome To Golgi Phospholipid Translocation	Mitochondrial Fission Autophagy Of Mitochondrion Mitochondrial Transport Mitochondrion Organization Synapse Assembly Respiratory Chain Complex IV Assembly Dendrite Development Optic Nerve Development Cerebellar Purkinje Cell Differentiation Myelination In Peripheral Nervous System Locomotion Involved In Locomotory Behavior Cristae Formation Peripheral Nervous System Neuron Axonogenesis Establishment Of Localization In Cell Phospholipid Homeostasis Axon Development Protein-containing Complex Assembly Mitochondrial Membrane Fission
Pathways
Drugs
Diseases
GWAS			Allergic disease (asthma, hay fever and/or eczema) (age of onset) ( 32603359) Allergic disease (asthma, hay fever and/or eczema) (multivariate analysis) ( 32603359) Allergic disease (asthma, hay fever or eczema) ( 29083406 29785011) Allergic sensitization ( 23817571) Asthma ( 34103634 31959851 31619474 30929738 29273806 27182965) Asthma (adult onset) ( 30929738 31036433) Asthma (age of onset) ( 31036433) Asthma (childhood onset) ( 30929738 31036433) Asthma and hay fever ( 24388013) Asthma onset (childhood vs adult) ( 30929738) Asthma or allergic disease (pleiotropy) ( 29785011) Cardiac structure and function ( 19584346) Medication use (adrenergics, inhalants) ( 31015401) Medication use (antihistamines for systemic use) ( 31015401) Thrombin-activatable fibrinolysis inhibitor levels ( 29378355) Uterine fibroid size (maximum volume) ( 30196971)
Interacting Genes		24 interacting genes: ADH5 AQP6 BEST2 CD79A CLCN7 DIABLO FBLN1 FUNDC2 GJA8 GPR152 IL10RA KCNK5 MGLL RHBDD1 SLC10A1 SLC10A6 SLC25A46 SLC35E3 SLC71A2 STX12 TMEM31 TMEM44 TMEM80 ZFYVE27	16 interacting genes: AQP6 FHL3 FUNDC1 HSD17B11 HSD17B13 LEPROTL1 ODF4 REEP2 REEP4 SLC10A1 SLC10A6 SLC66A2 SLC71A2 SLC7A8 SPCS1 VMA21
Entrez ID		80148	91137
HPRD ID		11454	14283
Ensembl ID		ENSG00000122490	ENSG00000164209
Uniprot IDs		K7ERV4 Q8N2U9	B4DY98 Q96AG3
PDB IDs			8TMU
Enriched GO Terms of Interacting Partners?		Transmembrane Transport Membrane Bile Acid:sodium Symporter Activity Chloride Transmembrane Transport Chloride Transport Bile Acid And Bile Salt Transport Inorganic Anion Transmembrane Transport S-(hydroxymethyl)glutathione Dehydrogenase (NADP+) Activity Formaldehyde Dehydrogenase (NAD+) Activity S-(hydroxymethyl)glutathione Dehydrogenase (NAD+) Activity Nitrate Transmembrane Transporter Activity Monoatomic Anion Transmembrane Transport Inorganic Anion Transport Channel Activity Monoatomic Anion Transport Monoatomic Ion Transport Interleukin-10 Binding Organic Hydroxy Compound Transport Intracellularly Ligand-gated Monoatomic Ion Channel Activity Nucleotide-sugar Transmembrane Transporter Activity Sodium-dependent Organic Anion Transmembrane Transporter Activity Sodium-dependent Organic Anion Transport	Steroid Dehydrogenase Activity Bile Acid:sodium Symporter Activity Bile Acid And Bile Salt Transport Estradiol 17-beta-dehydrogenase [NAD(P)+] Activity Endoplasmic Reticulum Tubular Network Endoplasmic Reticulum Tubular Network Organization Nitrate Transmembrane Transporter Activity Membrane Taste Receptor Binding Sodium-dependent Organic Anion Transmembrane Transporter Activity Sodium-dependent Organic Anion Transport PH-gated Chloride Channel Activity Nitrate Transmembrane Transport Carboxylic Acid Transport Organic Acid Transport Endoplasmic Reticulum Oxidoreductase Activity, Acting On The CH-OH Group Of Donors, NAD Or NADP As Acceptor Endoplasmic Reticulum Organization Cytoplasmic Microtubule Carbon Dioxide Transmembrane Transporter Activity Transmembrane Transport Carbon Dioxide Transmembrane Transport Lipid Transport Symporter Activity Organic Anion Transport Tryptophan Transport L-alanine Transmembrane Transport L-leucine Transmembrane Transporter Activity L-leucine Import Across Plasma Membrane L-alanine Import Across Plasma Membrane Valine Transport Signal Peptidase Complex Androgen Catabolic Process Lipid Droplet Protein Transport Into Membrane Raft Sensory Perception Of Sweet Taste Sensory Perception Of Bitter Taste Vacuolar Proton-transporting V-type ATPase Complex Assembly Proline Transmembrane Transport Glycine Transmembrane Transporter Activity L-alanine Transmembrane Transporter Activity Monocarboxylic Acid Transport Toxin Transmembrane Transporter Activity Thyroid Hormone Transmembrane Transporter Activity Proton-transporting V-type ATPase Complex Assembly Monoatomic Anion Channel Activity Ammonium Channel Activity Renal Water Transport Bile Acid Transmembrane Transporter Activity L-alanine Transport
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