SYT2 and STON2

Number of citations of the paper that reports this interaction (PMID 11381094)
45

Data Source:
BioGRID (affinity chromatography technology, pull down)
HPRD (in vivo, in vitro)

		SYT2	STON2
Gene Name		synaptotagmin II	stonin 2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane Cell Junction Synaptic Vesicle Membrane Chromaffin Granule Membrane Intracellular Membrane-bounded Organelle	Nucleolus Cytoplasm Synaptic Vesicle Cell Junction Clathrin Adaptor Complex Clathrin-coated Vesicle Neuron Projection
	Molecular Function	Transporter Activity Calcium Ion Binding Protein Binding Calcium-dependent Phospholipid Binding	Protein Binding
	Biological Process	Transport Pathogenesis	Hematopoietic Progenitor Cell Differentiation Intracellular Protein Transport Regulation Of Endocytosis Synaptic Vesicle Endocytosis
Pathways		Uptake and actions of bacterial toxins Toxicity of botulinum toxin type B (BoNT/B) Neurotoxicity of clostridium toxins
Drugs
Diseases
GWAS			Obesity-related traits ( 23251661)
Protein-Protein Interactions		5 interactors: KLHL3 NRXN1 STON2 SYNCRIP WNK1	6 interactors: AP2M1 EPS15 EPS15L1 ITSN1 SYT1 SYT2
Entrez ID		127833	85439
HPRD ID		02520	10531
Ensembl ID		ENSG00000143858	ENSG00000140022
Uniprot IDs		Q8N9I0	Q8WXE9
PDB IDs			2JXC
Enriched GO Terms of Interacting Partners?		Protein Complex Assembly Involved In Synapse Maturation Gamma-aminobutyric Acid Receptor Clustering Guanylate Kinase-associated Protein Clustering Neuroligin Clustering Gephyrin Clustering Synaptic Vesicle Clustering Distal Tubule Morphogenesis Developmental Process Vesicle Localization Renal Sodium Ion Absorption Neuronal Signal Transduction Negative Regulation Of Pancreatic Juice Secretion Renal Sodium Ion Transport N-methyl-D-aspartate Receptor Clustering Vocal Learning CRD-mediated MRNA Stabilization Negative Regulation Of Filopodium Assembly Postsynaptic Membrane Assembly Synapse Maturation Regulation Of Grooming Behavior Presynaptic Membrane Assembly Postsynaptic Density Protein 95 Clustering Receptor Localization To Synapse Cell Differentiation Presynaptic Membrane Organization Auditory Behavior Positive Regulation Of Systemic Arterial Blood Pressure Renal Absorption Cerebellar Granule Cell Differentiation Distal Tubule Development Organelle Localization Vocalization Behavior Prepulse Inhibition Neuron Cell-cell Adhesion Positive Regulation Of Synapse Maturation Mechanosensory Behavior Cerebellar Granular Layer Morphogenesis Response To Auditory Stimulus Regulation Of Synapse Maturation Protein Localization To Synapse System Development Regulation Of Alpha-amino-3-hydroxy-5-methyl-4-isoxazole Propionate Selective Glutamate Receptor Activity Membrane Assembly Regulation Of N-methyl-D-aspartate Selective Glutamate Receptor Activity Positive Regulation Of Synaptic Transmission, Glutamatergic Cerebellar Granular Layer Development Positive Regulation Of Establishment Of Protein Localization To Plasma Membrane Membrane Biogenesis Positive Regulation Of Protein Localization To Plasma Membrane MRNA Stabilization	Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Negative Regulation Of ERBB Signaling Pathway Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Regulation Of ERBB Signaling Pathway Vesicle-mediated Transport Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Endocytosis Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Enzyme Linked Receptor Protein Signaling Pathway Transport Regulation Of Signaling Ephrin Receptor Signaling Pathway Fast, Calcium Ion-dependent Exocytosis Of Neurotransmitter Synaptic Transmission Synaptic Vesicle Transport Establishment Of Localization In Cell Cell-cell Signaling Establishment Of Vesicle Localization Pathogenesis Vesicle Localization Neurotrophin TRK Receptor Signaling Pathway Calcium Ion-dependent Exocytosis Of Neurotransmitter Neurotrophin Signaling Pathway Cellular Localization Negative Regulation Of Signal Transduction Negative Regulation Of Signaling Regulation Of Signal Transduction Establishment Of Organelle Localization Detection Of Calcium Ion Positive Regulation Of Calcium Ion-dependent Exocytosis Cell Surface Receptor Signaling Pathway Signaling Axon Guidance Cell Communication Golgi To Endosome Transport Organelle Localization Positive Regulation Of Vesicle Fusion Negative Regulation Of Protein Localization To Plasma Membrane Endocytic Recycling Glutamate Secretion Regulation Of Defense Response To Virus By Virus Axonogenesis Axon Development Cellular Response To Growth Factor Stimulus Cell Morphogenesis Involved In Neuron Differentiation Regulation Of Vesicle Fusion Chemotaxis Response To Growth Factor Clathrin Coat Assembly
Tagcloud ?		anion apical begin bring buffered ca2 chloromethylfluorescein cmfda conferring cytosolic diacetate disrupted epithelia hepatocytes inositol insp3r insp3rs mis peri polarized synaptotagmins syt1 syts tether tethered tethering tethers trisphosphate waves
Tagcloud (Difference) ?		anion apical begin bring buffered ca2 chloromethylfluorescein cmfda conferring cytosolic diacetate disrupted epithelia hepatocytes inositol insp3r insp3rs mis peri polarized synaptotagmins syt1 syts tether tethered tethering tethers trisphosphate waves
Tagcloud (Intersection) ?