STON2

Description		stonin 2
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GO Annotations	Cellular Component	Nucleolus Cytoplasm Cytosol Synaptic Vesicle Membrane AP-2 Adaptor Complex Neuron Projection Synapse
	Molecular Function	Protein Binding Clathrin Adaptor Activity
	Biological Process	Endocytosis Regulation Of Endocytosis Synaptic Vesicle Endocytosis Clathrin-dependent Endocytosis
Pathways		Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis
Drugs
Diseases
GWAS		Central corneal thickness ( 29760442 32528159) Estimated glomerular filtration rate ( 31152163) Metabolite levels ( 23823483) Night sleep phenotypes ( 27126917) Obesity-related traits ( 23251661) Platelet count ( 27863252 32888494) Plateletcrit ( 27863252 32888494) Prudent dietary pattern ( 28644415)
Interacting Genes		8 interacting genes: AP2M1 EPS15 EPS15L1 H19 ITSN1 SYT1 SYT2 UBC
Entrez ID		85439
HPRD ID		10531
Ensembl ID		ENSG00000140022
Uniprot IDs		A0A3B3IU55 H0YJ05 Q8WXE9
PDB IDs		2JXC
Enriched GO Terms of Interacting Partners?		Vesicle-mediated Transport In Synapse Clathrin-coated Pit Synaptic Vesicle Endocytosis Presynaptic Endocytosis Vesicle-mediated Transport Clathrin-coated Endocytic Vesicle Membrane Postsynaptic Neurotransmitter Receptor Internalization Clathrin Coat Of Coated Pit Chromaffin Granule Membrane Postsynaptic Endocytic Zone AP-2 Adaptor Complex Calcium-dependent Activation Of Synaptic Vesicle Fusion Synapse Dense Core Granule Endocytosis Calcium Ion Sensor Activity Positive Regulation Of Dendrite Extension Positive Regulation Of Vesicle Fusion Regulation Of Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane Receptor-mediated Endocytosis Low-density Lipoprotein Particle Receptor Binding Exocytic Vesicle Regulation Of Vesicle-mediated Transport Glutamatergic Synapse Clathrin-dependent Endocytosis Calcium Ion Binding Import Into Cell Protein-macromolecule Adaptor Activity Regulation Of Vesicle Fusion Regulation Of Calcium Ion-dependent Exocytosis Endosomal Transport Regulation Of Synaptic Vesicle Exocytosis Calcium-dependent Phospholipid Binding Establishment Of Localization In Cell Vesicle Organization Positive Regulation Of Transport Cytoplasmic Vesicle SNARE Binding Receptor Internalization Regulation Of Postsynaptic Membrane Neurotransmitter Receptor Levels Fast, Calcium Ion-dependent Exocytosis Of Neurotransmitter Synchronous Neurotransmitter Secretion Endocytic Vesicle Membrane Plasma Membrane Regulation Of Neurotransmitter Secretion Clathrin-dependent Synaptic Vesicle Endocytosis Syntaxin-3 Binding Positive Regulation Of Cellular Component Organization Intracellular Transport Positive Regulation Of Calcium Ion-dependent Exocytosis Of Neurotransmitter
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